Telias Lab

On March 31st this twitter account will stop existing. If you'd like to follow the Telias Lab, please connect with me through LinkedIn: linkedin.com/in/michael-tel…

March 1st 2026: Our move to the Dept. of Ophthalmology at @PittTweet @pitt_medicine is 1 mo away! Great time to share exciting results: a repurposed drug preserves photoreceptors in RP mice thanks to support by @RPB_org and @NatEyeInstitute @NEIDirector

First batch of individual mouse data for innate light avoidance using a custom built multimodal dual-chamber light box. The box can also project a looming dot and the same friendly code can retrieve results immediately. #mouse_visual_behavior #Neuroscience

@BoWang87 I never learned a "rule" that viruses were not alive. It was always an open discussion whether to classify them as alive or not. You present the argument as if someone had decided they are not alive and made that into a rule. That is not the case.

Harvard scientists just shattered one of biology’s oldest rules. We were taught: Viruses can’t make their own proteins. They hijack yours. That’s why they’re “not alive.” Except giant DNA viruses just crossed that line. Researchers found they carry a full eukaryotic-style translation complex (vIF4F). Translation machinery. Inside a virus. They can keep making proteins even under stress that shuts down normal viral replication. If a virus brings its own protein-making tools… Is it still just a parasite? For decades we’ve drawn a clean boundary: Cell = alive Virus = not alive Nature doesn’t care about our categories. Maybe viruses aren’t just evolutionary side notes. Maybe they helped build complex life. Paper in Cell 👇 cell.com/cell/fulltext/… Harvard news: cellbio.hms.harvard.edu/recent-researc…

This beauty is not just "another" crazy complex RGC image. This image is the result of amazing longitudinal in-vivo imaging of single mouse RGCs made possible by #AOSLO in the @schalleklab with funding from @NIH @NatEyeInstitute

@ShiningScience @grok can you find the citation/paper that this post supposedly portrays? Is the description in this post based to any peer-reviewed publication?

🚨 New research shows quantum states in the brain may link consciousness to the entire universe. In a fascinating convergence of physics and neuroscience, recent research suggests that human consciousness may function as a quantum phenomenon—one that connects our minds with the broader universe. Building on the controversial Orch OR (Orchestrated Objective Reduction) theory, scientists are now producing experimental evidence that supports the idea that microtubules—structures within brain cells—can maintain quantum coherence, even in the brain’s warm, wet environment. These quantum states could be the key to consciousness existing as a wave capable of superposition and entanglement, potentially linking human awareness to quantum systems across space. This theory has gained new traction thanks to simulations and experiments showing that quantum reactions can persist inside microtubules for significantly longer than expected. Meanwhile, theoretical physicist Timothy Palmer suggests that consciousness may reside in a cosmic fractal “state space”—a shared geometric structure that might explain both free will and our sense of being interconnected with the universe. While not yet definitive, this research marks a critical step toward understanding consciousness as more than a neural illusion: it may be a quantum feature of reality itself.

@ShiningScience Where is the citation? Link to the paper please.

The gene therapy shift: Today, the concept of gene therapy is not only well understood but is also a clinical reality that may soon become a therapeutic option in the retina specialist’s armamentarium. hubs.li/Q0439Cqm0

GFP-NLS expressing mouse neurons, right after seeding, about to get growing inside the 4-chamber Xona chip for the first time in our hand. Any advice? Images courtesy of Telias Lab Postdoc Dr. Yusof Gusti.

👏👏👏👏👏👏

These little neurons are shining bright with an GFP expressed exclusively in the nucleus. Exciting developments to understand whether neuronal axons can guide photons as fiber optics do. Stay tuned. Prject generously funded by the @templeton_fdn

New review from @TeliasLab in Frontiers in Ophthalmology shows that tiny RNAs in eye fluid can signal retinal disease. miR-142, miR-9, and miR-21 are strong biomarker candidates. doi.org/10.3389/fopht.… #URochesterResearch @FlaumEye

This is the most detailed model of a human cell ever created, using data from X-ray, NMR, and cryoelectron microscopy. ‘Cellular landscape cross-section through a eukaryotic cell.’ - Evan Ingersoll & Gael McGill.

You might think nobody is watching you, but we are keeping track of every move you make... 🤫🤫🤫

First raw acquisition of retinal ganglion cell images in-vivo, using #AOSLO in collaboration with the great @schalleklab by our amazing postdoc Dr. Belhadj.

As we close out the year, we want to thank partners, researchers, patients, and advocates who stood with us through uncertainty, challenge, and momentum-building progress. Your support made it possible to elevate vision research, protect critical federal funding, #SeeWhatMatters

record braking longest mouse tail in history 😅😅😅

@eLife wrong link

Findings reveal how TGF-beta signalling keeps the brain’s blood vessels healthy. Disrupting this in brain blood vessels disrupts retinal development and triggers immune cell invasion, revealing its role in maintaining vascular–immune balance in the CNS. elifesciences.org/articles/10937…

youtube.com/watch?v=WwMsJ7… youtube.com/watch?v=3Mtkwt…

New article: can we use microRNAs from vitreous biopsies to diagnose and understand retinal diseases? frontiersin.org/journals/ophth…