David Fierling

493 posts

David Fierling

David Fierling

@davidfierling

Beigetreten Şubat 2010
57 Folgt5 Follower
Nic Cruz Patane
Nic Cruz Patane@niccruzpatane·
It has begun, Elon was right. Mercedes has started to remove LiDAR sensors from its new vehicles. The all-new 2027 Mercedes-Benz C-Class EV does not feature any LiDAR sensors in its suite, as does the new CLA EV. • 10 cameras • 5 radars • 12 ultrasonic sensors • 0 LiDAR Mercedes says the decision to remove LiDAR comes primarily for cost, and scalability.
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Bryan Johnson
Bryan Johnson@bryan_johnson·
I put ice on my balls during sauna and my motile count went up 57%. Then I removed the ice and motility crashed 57%. 238 sessions to learn that the most important variable in my sauna protocol was a bag of ice on my groin. I am a serious scientist.
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theburntpeanut
theburntpeanut@theburntpeanut·
BUNGULATORS!!! We are running a 2 PC giveaway. 2x RTX 5070 STARFORGE Gaming PC Bundles. To Enter, perform these Task via the Link Below: 🔁Repost + Like ✅Follow All Official Burnt Peanut Channels vast.link/peanut
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Bryan Johnson
Bryan Johnson@bryan_johnson·
If you have a non-stick cookware. Get rid of it. New study: a 169% increase in the risk of fatty liver disease in adolescents is linked to PFOA, a forever chemical used in non-stick cookware, with every doubling of exposure. I've been meticulously measuring these toxin levels in myself and drinking water. Significant study findings: + PFOA showed the highest risk increase for fatty liver disease in adolescents; each doubling of PFOA plasma concentration was associated with a 169% increased odds of fatty liver disease. + In one cohort, each doubling of PFHpA was associated with a 73% increased risk of fatty liver disease in adolescents. + Age mediated the risk posed by PFOA in adolescents; each year increase in age added a 45% increased odds of fatty liver disease for every doubling of PFOA plasma concentration. + The high-risk PNPLA3 genotype significantly increased the risk of fatty liver disease with PFAS exposure in adolescents, particularly for PFHxS. Each doubling in PFHxS concentration was associated with a 552% increase in fatty liver disease odds in older adolescents carrying the PNPLA3 GG high-risk phenotype. + No basic association with increased risk was observed with increasing PFAS concentrations in young adults. + Smoking in young adults turned several PFAS, including PFDA, PFHpS, and PFNA, into significant risk factors for metabolic liver disease. Added Context: + MASLD definition: Having >5.5% liver fat in addition to at least one metabolic disease criterion (high BMI, fasting glucose, blood pressure, triglycerides, and/or low HDL). + PNPLA3: A gene involved in fat and cholesterol handling and storage in the liver and adipose tissue. The GG phenotype predisposes its carriers to an increased risk of developing fatty liver and metabolic (non-alcoholic) liver disease. Significance: Known as "forever chemicals," PFAS persist for years or decades in the human body (PFOA has a half-life of 1.5–5 years) and for decades to centuries in the ecosystem (PFOA has a half-life of 92 years in environmental water). PFAS are widely used as insulating and non-stick materials in non-stick cookware, clothing, electronics, and many other household and industrial applications. PFAS have long been known to cause metabolic and endocrine disruptions, affecting metabolism, insulin function, and liver fat metabolism. Adolescence and early adulthood are particularly sensitive phases due to hormonal changes around puberty and related rapid growth, making this age group especially vulnerable to the endocrine, hormonal, and metabolic damage caused by PFAS. This study successfully identified adolescents as an especially vulnerable risk group to specific types of PFAS (PFOA and PFHpA). Given that PFOA is used in non-stick ware and other food containers, this highlights the importance of avoiding these items in households with children, especially around and after the age of puberty. Furthermore, the study uncovered the exacerbation of genetic risk by PFAS, indicating that PNPLA3 GG carriers should be especially aware of the risk from PFHxS. This chemical is commonly used in firefighting foams, water-repellant clothing and polishes, as well as various electronics. Young adults showed no basic association between PFAS and liver disease risk, possibly indicating a special sensitivity before and around puberty. However, smoking altered this relationship, making young-adult smokers more susceptible to increased liver disease risk with PFAS exposure. Limitations While the study offers several actionable insights, more research is needed to determine if the findings hold for non-Hispanic adolescent populations (as the SOLAR adolescent cohort was solely of Hispanic background). Additionally, the somewhat small sample size limits the study's statistical power. Finally, the single-time point PFAS exposure assessment and the cross-sectional nature of the study make it impossible to assess cumulative exposures or draw any causative conclusions, limiting the insights to observational findings.
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NZXT
NZXT@NZXT·
Who needs a new PC for Christmas? 🎅
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David Fierling
David Fierling@davidfierling·
@ronmortgageguy Did the 90s bubble affect cottage prices the same way What kind of % drop should we expect over the next few years
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Ron Butler
Ron Butler@ronmortgageguy·
Ontario Real Estate Market Gets Better Next Year? NOPE Time For A History Lesson I was around for the last Ontario RE Bubble History doesn't really repeat itself & nothing is ever a perfect duplicate But... Similarities are startling 1990 the raging Ontario Market STOPPED 2/
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NVIDIA ANZ
NVIDIA ANZ@NvidiaANZ·
🎄‘Tis the #GeForceSeason of RTX 🎄 We’re celebrating every Season of Play. Get ready for new reveals, exclusive rewards, and epic deals. 🟢 Custom wrapped cards 🟢 Steam cash drops 🟢 GeForce Rewards + MOAR Comment "GeForce Season" for a first chance at Steam Cash 💸
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NVIDIA ANZ
NVIDIA ANZ@NvidiaANZ·
❄️ #GeForceSeason of Giving ❄️ Slayers, want your shot at a DOOM: The Dark Ages custom-wrapped GeForce RTX 5090? Comment “GeForce Season” below and tell us why you deserve to unleash its mayhem this holiday. ⚔️
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AORUS Australia & New Zealand
BLACK FRIDAY BOSS MODE ACTIVATED🎮 Grab insane deals on GIGABYTE/AORUS gaming laptops and monitors — faster refresh, sharper visuals, and pro-tier performance. 💻Laptop: Up to 30% Off 🖥Monitor: Save up to $400 Plus Bonus Steam Rewards - coming soon! Gear up before the clock runs out.⏳⚔️
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David Fierling
David Fierling@davidfierling·
@GlobalLianli almost 3 weeks and i have not heard anything back from lian li warranty claim, no confirmation email...nothing love the products but the support sucks
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David Fierling
David Fierling@davidfierling·
@LinusTech Paint rant. Not sure if it was a hot take but damn he took that serious
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Linus Tech Tips
Linus Tech Tips@LinusTech·
Linus has had some pretty hot takes in his career. Some have aged well, some haven't... Let us know your favorite hot take from Linus and it may be used in an upcoming video!
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Elon Musk
Elon Musk@elonmusk·
Just bought a new PC laptop and it won’t let me use it unless I create a Microsoft account, which also means giving their AI access to my computer! This is messed up. There used to be an option to skip signing into or creating a Microsoft account. Are you seeing this too?
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David Fierling
David Fierling@davidfierling·
@Model3Owners I tried once and I just can’t like a game that is made for commercials More of a soccer and f1 fan
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MrBeast
MrBeast@MrBeast·
I’m gonna give 10 random people that repost this and follow me $25,000 for fun (the $250,000 my X video made) I’ll pick the winners in 72 hours
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David Fierling
David Fierling@davidfierling·
@JayzTwoCents Before and after of my under the stairs nook. Sorry about the Linus face
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JayzTwoCents
JayzTwoCents@JayzTwoCents·
Let's do this again! Show us your best and WORST setups!
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