CharlieBio

AI Found the Key to Pre-Symptom Alzheimer’s In a major leap for predictive medicine, a research team has unveiled FINGERS-7B, the first AI foundation model designed specifically to prevent Alzheimer’s disease. The model achieves 4× more accurate preclinical diagnosis by integrating a massive array of data, including lifestyle, genomics, and proteomics, into a single “biological fingerprint.” By identifying the disease up to a decade before symptoms appear, FINGERS-7B aims to transform Alzheimer’s from an inevitable decline into a manageable, and potentially preventable, condition. neurosciencenews.com/fingers-7b-alz… #AI #Alzheimers #Neuroscience (1/3)

The cancer immunotherapy saving lives today? It started 30-40 years ago with scientists just following their curiosity. President Sally Kornbluth joined Lizzie O’Leary of Slate’s "What Next: TBD" podcast. Basic science isn't always flashy, but it's how we get to the breakthroughs that matter. Sometimes the best investments take decades. youtu.be/N6ETeg7dgkw?si…

¿Cómo es el aire donde vives? La Nota de Acción del PNUMA sobre la Contaminación del Aire muestra datos sobre la calidad del aire, sus impactos en la salud y las acciones que están tomando los países para vivir #SinContaminaciónDelAire. En inglés: unep.org/interactives/a…

A new study in Communications Earth & Environment reveals a striking shift already underway in the Southern Ocean: warming deep waters are moving closer to Antarctica, putting ice shelves under increasing pressure from below. time.com/article/2026/0…

New high-altitude measurements have revealed a hidden population of extremely small, organic-rich aerosol particles in the lower stratosphere. The findings in Science suggest that these ultrafine aerosols, likely lofted from the underlying troposphere, are far more abundant and chemically influential than previously understood. scim.ag/48pBPUM

Members of the US Congress have signaled that they will once again reject a proposal by the Trump administration to slash science spending. But the bill they advanced today still calls for substantial cuts to budgets at agencies such as the National Science Foundation. go.nature.com/48xUaPw

🌡️ @UCLA & @UAI_CL research shows the longest, rarest heatwaves – lasting weeks – will accelerate fastest as the planet warms. 📈 We need detailed foresight to plan & adapt for a hotter future. 👉 ow.ly/KGlr50WFUM7 #BeatTheHeat

Pastel de choclo | 🇨🇱 A beloved traditional Chilean casserole!

CERN's "How Small is an Atom?" zooms from a human hair (100μm) down to quarks! Atoms are ~0.1 nm wide; millions fit across one strand. 99.99% empty space around a tiny nucleus of protons & neutrons (made of quarks). Building blocks of everything.

Crece la expectativa sobre el rescate de la ballena Timmy Más de un mes después de quedar varada en la costa báltica de Alemania, la ballena Timmy sigue con vida tras un rescate que inicialmente se creía inviable. Ahora es remolcada en una barcaza especialmente adaptada hacia el Mar del Norte, desde donde podría alcanzar el Atlántico. Pero su pronóstico sigue siendo incierto y la arriesgada operación divide a los expertos.

With student A.I. use/abuse now ubiquitous, professors and teachers are killing off take-home essays and papers. Students are writing inside the classroom, often by hand. It's part of the big rethink happening on tech and learning. My new report here: nytimes.com/2026/04/30/us/…

Una pintura de 1562 desata la teoría de que dinosaurios convivieron con humanos Durante siglos nadie vio nada raro en ese cuadro. Luego internautas ampliaron una esquina del lienzo y creyeron ver algo insólito. (few) p.dw.com/p/5D4mq

Qué pasó en Países Bajos dos años después de prohibir el uso del celular en todas las escuelas. #LosLagos #LosRios Valdiviacl Osorno #PuertoMontt Frutillar #PuertoVaras Castro Ancud Chiloe Panguipulli #LagoRanco #SantiagodeChile Temuco Educación Tecnologia bbc.com/mundo/articles…

🧟‍♂️ ¡Los zombis pueden ser más que ficción! La investigación sobre el "polvo zombi" y la tetrodotoxina revela un mundo oscuro y fascinante. La ciencia y el vodou se entrelazan en esta misteriosa realidad. 🧠👇

Solar panels fitted every three minutes in UK since Iran conflict #Echobox=1777578933" target="_blank" rel="nofollow noopener">thetimes.com/uk/environment…

@jorgeed26794627 Asi con la historia del puente Valdiviacl #LosRios @mop_chile losrios.mop.gob.cl/vecinos-conoce…

Un maldito puente angosto que data del año 1942 .. y ninguna autoridad ha tenido la fuerza para hacer otro 😡😡 #valdiviacl

A regional analysis brought together data on wild-animal consumption by more than 12,000 households, to investigate trends and drivers of wild-meat use across Central Africa. go.nature.com/4dhvTQk

What’s the air like where you live? UNEP’s Pollution Action Note shows data on air quality, its health impacts and the actions countries are taking to #BeatAirPollution: unep.org/interactives/a…

Data is cheap. Insight is expensive. Storytelling is priceless.

Your morning coffee cuts dementia risk by 18%. Decaf does nothing. Harvard tracked 131,821 people for 43 years to figure out why. Caffeine is an adenosine antagonist. Adenosine is the molecule that builds up in your brain through the day and makes you sleepy. It also dampens the neurotransmitters involved in memory formation. Caffeine blocks the receptor before adenosine can lock in. Memory circuits run less suppressed than they would otherwise. That's why decaf failed. Decaf has the same polyphenols as regular coffee. Same antioxidants. Same magnesium. The only thing missing is the molecule that blocks the adenosine receptor. If polyphenols were doing the work, decaf would have shown a partial effect. It showed zero. The most interesting part: the protective effect held even in people with high genetic risk for dementia. Genes load the gun. Coffee slows the trigger pull. The dose-response curve plateaus around 3 cups. Five cups didn't beat three. Past saturation, additional coffee buys you jitters and nothing else. Coffee is the most consumed psychoactive drug on the planet. Two billion cups per day. We've spent decades treating it like a mild vice. Turns out it's the largest accidental dementia prevention program in human history.