Freund_Lab@FUB

55 posts

Freund_Lab@FUB

@LabFreund

We aim to relate protein structure and dynamics to biology and human disease in the fields of immunology and neurobiology.

Joined Ağustos 2020

66 Following141 Followers

Freund_Lab@FUB retweeted

Francesca Bottanelli@Fran_Bottanelli·29 Ağu

Great to finally see this online @J_Cell_Sci journals.biologists.com/jcs/article/13… I hope it is a great resource for everybody embarking in proximity labelling #masspec experiments! I promise all plasmids will be on @Addgene in the next few weeks! @A_STEDhammer @LabFreund

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Freund_Lab@FUB retweeted

Haucke lab@VolkerHaucke·14 Kas

We have an opening for a master’s thesis (biochemistry, mol. biology) on the characterization of novel small molecules targeting class II PI 3-kinase function (see Lo et al Nat Chem Biol 2023) starting 1 January 2024 (or later). Interested? Apply to haucke@fmp-berlin.de!

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Freund_Lab@FUB retweeted

Francesca Bottanelli@Fran_Bottanelli·27 Eki

3 first authors! 2 papers! Looking forward to getting feedback from the community! @A_STEDhammer @petiaadarska @FreeThePipette

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Freund_Lab@FUB retweeted

Francesca Bottanelli@Fran_Bottanelli·27 Eki

Wondering how cargo is shuttled around between compartments in the cell? We think it is via dynamic tubular vesicular compartments! Check out our two new pre-prints biorxiv.org/content/10.110… and biorxiv.org/content/10.110…

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Freund_Lab@FUB@LabFreund·28 Eyl

@NaWiSchool Schön, dass ihr bei uns zu Besuch wart! Es wäre schön, wenn wir bald ein paar young scientists bei uns wieder begrüßen dürfen! :)

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Freund_Lab@FUB retweeted

NaWi School e.V.@NaWiSchool·28 Eyl

Die Gespräche der jungen Leute mit den Wissenschaftlern fanden die Teilnehmer aufschlussreich und interessant. Es war der Höhepunkt des Tages. Danke an Herrn Dähn shorturl.at/clDSY

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Freund_Lab@FUB retweeted

Haucke lab@VolkerHaucke·22 Eyl

Proud to share Svenja's paper in Neuron on the coupling of exo- and endocytosis via Synaptotagmin-triggered signaling lipid synthesis: cell.com/neuron/fulltex… Take a look! Congrats to Svenja and everyone involved!

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Freund_Lab@FUB retweeted

Haucke lab@VolkerHaucke·8 Eyl

Please check out our new review on commonalities between vesicular and nonvesicular transport via intrinsically disordered proteins! Hope you will like it!

EMBO Reports@emboreports

New #review alert! Read on how intrinsically disordered proteins orchestrate #vesicular and nonvesicular #transport and #neuronal activity. #intrinsicdisorder #IDP @VolkerHaucke @LeibnizFMP Stephan Sigrist @FU_Berlin ➡️ embopress.org/doi/full/10.15…

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Freund_Lab@FUB retweeted

Ewerslab@ewers_helge·25 Ağu

New on BioRxiv: We investigate the fundamentalest of organelles, the plasma membrane. We finally show experimentally, that submembrane actin cables cause the compartmentalization of membrane protein motion that has been observed for decades. A tweetorial. biorxiv.org/content/10.110…

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Freund_Lab@FUB retweeted

Freie Universität@FU_Berlin·3 Ağu

Umfrage zeigt: Durchschnittlich liegen zwischen Wohnort und FU-Campus 17 Kilometer. Warum @fu_berlin eine „Universität der öffentlichen Verkehrsmittel“ ist und wie die Mobilität auf dem Campus noch rad-, fuß- und klimafreundlicher gestaltet werden kann⬇️ fu-berlin.de/campusleben/ca…

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Freund_Lab@FUB@LabFreund·28 Tem

@AgataWitkowska @NeuroCureBerlin @LeibnizFMP Congratulations 👏🎉

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Agata Witkowska@AgataWitkowska·26 Tem

I am really honored to be awarded the @NeuroCureBerlin fellowship🤩. Stay tuned because soon I will be hiring a PhD student and a research assistant for this exciting project at the interface of #MolecularNeuroscience and #MembraneBiophysics @LeibnizFMP 🥳

NeuroCure Cluster of Excellence@NeuroCureBerlin

👏🏼Congrats👏🏼 to the new NC #Research Fellows 2023! @AgataWitkowska, Dorothee Kübler-Weller, @RosannaSammons & @IlonLiu have been awarded NeuroCure Research #Fellowhips for #female postdocs in the #neurosciences! Stay tuned for more information! bit.ly/43KWkGh

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Freund_Lab@FUB retweeted

DGZ, @DGZ.bsky.social@DGZ_info·19 Haz

@Fran_Bottanelli and @AnneStraube assembled the program for the 2nd #DGZ Focus Workshop on #MembraneTrafficking & #MolecularMotors, featuring Erik Schaeffer @schaeffer_lab, Harriet Saunders (Akhmanova lab), Claire Friel @FrielLab, & Felix Frey @sciFelixFrey. Join us next week! ⬇️

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Freund_Lab@FUB retweeted

Raluca Groza@RaluucaG·27 Haz

the preprint of my PhD work is now available, make sure to check it out!

Ewerslab@ewers_helge

New on BioRxiv: Adhesion energy controls lipid-binding mediated endocytosis. A group effort lead by @RaluucaG with contributions from our friends @taraskalab @DimovaLab @cmatthaeus2 and Thomas Weikl @MpiciPotsdam @FUBiochemistry @FU_Berlin biorxiv.org/content/10.110…

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Freund_Lab@FUB@LabFreund·27 Haz

@Fran_Bottanelli @ishier_raote @RangamaniUCSD @StachowiakLab Definitely an interesting take to actin bundling! Thanks for linking us to the article :)

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Francesca Bottanelli@Fran_Bottanelli·27 Haz

@ishier_raote @RangamaniUCSD @StachowiakLab This may be a good read for @LabFreund

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Ishier Raote@ishier_raote·27 Haz

Another fun preprint from @RangamaniUCSD and @StachowiakLab! They earlier showed VASP liquid-like condensates catalyse actin polymerization / bundling. Here, the VASP condensates mediate competition between actin branching (via Arp2/3) and actin bundling. biorxiv.org/content/10.110…

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Freund_Lab@FUB retweeted

Stricker Lab@LabStricker·9 Haz

Please re-tweet !!! The Stricker Lab looks for highly motivated NEW Team members at all career stages! If you are excited bout CRISPR, reprogramming, epigenome editing in organoids and in vivo please contact us!

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Freund_Lab@FUB@LabFreund·15 May

Thanks @FU_Berlin to highlight our work! fu-berlin.de/presse/informa…

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Freund_Lab@FUB@LabFreund·8 May

New paper @nchembio. With @Esam_Abualrous @FrankNoeBerlin we show that the popul. of a transient state of the catlyzed peptide exchange of MHC class 2 has a predictive value and dynamics correlate with odds ratio for autoimmune disease rheumatoid arthritis nature.com/articles/s4158…

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Freund_Lab@FUB retweeted

Nature Chemical Biology@nchembio·5 May

A new paper from @LabFreund used a computational and experimental approach to detect peptide exchange of twelve abundant MHCII allotypes that enables responsiveness to HLA-DM catalysis. Open access.

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Freund_Lab@FUB retweeted

Francesca Bottanelli@Fran_Bottanelli·27 Nis

A tour the force of #geneediting and #STED. We have followed up on some of these findings and have 2 papers that will drop soon! looking at endogenous proteins at high resolution in their own unperturbed cellular environment is helping to reveal important trafficking mechanisms!

Journal of Cell Biology@JCellBiol

.@freethepipette, @fran_bottanelli and colleagues combine gene editing and STED super-resolution #microscopy to reveal the nanoscale localization of ARF #GTPases in living cells bit.ly/3HhBHcp

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Freund_Lab@FUB retweeted

Freie Universität@FU_Berlin·24 Nis

3. Mai 23, 18 Uhr: @fubcp Vortragsreihe „Dahlemer Wissenschaftsgespräche“, Thema: „Membranproteine sind Nanomaschinen – Wie neue physikalische Methoden deren Funktionsmechanismus auf atomarer Ebene aufklären“. @PhysikFUBerlin 👇 fu-berlin.de/presse/informa…

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@J_Cell_Sci @Addgene @petiaadarska @FreeThePipette @NaWiSchool @fu_berlin @AgataWitkowska @NeuroCureBerlin