Matt Hemming

Now out in @CR_AACR: We mine the epigenetic underpinnings of #AlveolarSoftPartSarcoma utilizing patient samples, preclinical models, and functional tags (dTAG, BioID) to define the oncogenic transcriptional program driven by ASPSCR1::TFE3 and actionable therapeutic liabilities:

Federal funding for US biomedical research is moribund. Since October 1 2025, NIH is -80% in new grants and -70% in values (total dollars). Labs are closing down and researchers are leaving science. To what end?

Favour Akabogu is passionate about understanding disease mechanisms and developing therapeutic strategies for treatment. She is currently a PhD candidate in the Sarcoma Lab at @UMassChan. awis.org/project/awis-m… #WomenInScience #MemberMonday

SFA is accepting applications for the 2026 Last Mile Sarcoma Research Award. This one-year, $150,000 grant supports sarcoma researchers seeking to strengthen the resubmission of R01 or equivalent proposals focused on advancing the understanding and treatment of sarcoma. Applications are due by February 2, 2026, at 5:00 pm ET. #sarcoma #curesarcoma #sarcomaresearch

Honored to present @UMass_Medicine Grand Rounds at @UMassChan and @UMassMemorial—sharing the history and complexities of #Sarcoma, and a vision for research and innovation to improve care for patients facing these rare cancers. Recording available here: umassmed.edu/medicine/educa…

The highlight of the Strategic Advances in Sarcoma Science (SASS) conference @NIH was the phenomenal work presented by @FavourFavvycool, @YiHsuanH83, and many others! Energizing advocacy for #Sarcoma research and terrific representation from @UMassChan @UMassCancerCtr.

The Department of Medicine would like to thank Dr. Matthew Hemming for presenting "Sarcoma: Rare Origins to Modern Insights — History, Clinical Care, Research and the Challenges Ahead" at today's Medical Grand Rounds! Music created and provided by Dr. Karen Salomon-Escoto.

Dr. Matt Hemming @SarcomaLab presented his research on exploiting metabolic dysregulation in SDH-deficient GIST, offering valuable insights into new strategies that may advance treatment options for this rare subtype. #CTOS2025 #GIST #SDHGIST #SarcomaResearch

Next week, our 2026 Research Grant application is closing. Submit your Letter of Intent by November 6 to be considered. SFA encourages applications in ALL areas of sarcoma research from both U.S. and international applicants. Researchers are invited to submit LOIs for proposals in pre-clinical, translational, and clinical research on the etiology, molecular biology, pathogenesis, diagnosis, and treatment of human sarcomas. Learn more about eligibility, funding details, and the review and selection process on our website at buff.ly/Hw5uaPv

We are looking for another #sarcoma medical oncologist!!!! Please reach out to me if you or some one you know is interested!!!!

Brilliant science and autumn inspiration at the UMass Cancer Biology Retreat @UMassChan @UMassCancerCtr! Kudos to @FavourFavvycool for an invited talk and @YiHsuanH83 for the TOP POSTER award — #Sarcoma research shining even brighter than the New England fall leaves!

To honor her late mother, PhD candidate @peura_jessica is studying how pancreatic cancer spreads. With an NIH fellowship, she developed a faster, more accurate research model to study metastasis at @UMassChan. #CancerResearch umassmed.edu/news/news-arch…

We are hiring @CUCancerCenter for #sarcoma faculty! Lots of patients, cutting edge clinical trials, a phenomenal multidisciplinary team, and all this with beautiful mountains to play in! DM me for details and feel free to share!

July is #SarcomaAwarenessMonth. This year, Michelle Cormier-Del Orbe, a #UMassMemorial patient diagnosed with stage 4 Malignant PEComa, made it her mission to illuminate the Burns Memorial Bridge in Shrewsbury/Worcester... and, she did it! #LightUpForSarcoma 📸: Joan Sanders

Read Pukkila-Worley, MD, is the new director of the MD/PhD program: direc.to/n8PN Dr. Pukkila-Worley has mentored dozens of MD/PhD graduate students since joining @UMassChan in 2014. The @RPWLab studies host-pathogen interactions and bacterial pathogenesis. @UMassMDPhD

🗣️ We're hiring a Director of Preclinical Research! This is an exciting opportunity for an oncology R&D leader to make a tangible impact in the lives of patients in urgent need of new treatment options. More info: chordoma.org/team/careers/

PhD candidate Favour Akabogu is working to develop new therapies for a rare type of sarcoma called gastrointestinal stromal tumor (GIST), a tumor that develops throughout the gastrointestinal tract: brnw.ch/21wTruo #StudentSpotlight #Research #PhD @SarcomaLab

Terrific spotlight by @UMassChan on PhD candidate @FavourFavvycool highlighting Favour’s outstanding accomplishments and work on #sarcoma & #GIST, and well-deserved accolades for her research and presentations! umassmed.edu/news/news-arch…

Another study- my recent work on Friedreich Ataxia just went online! @UMassChan With a targeted RNAi screen, we uncovered ROCK1/2 as key epigenetic silencers of FXN. jneurosci.org/content/early/… #FriedreichAtaxia #frataxinreactivation #DrugRepurposing

Congratulations to @YiHsuanH83 on passing her qualifying exam @UMassChan and advancing to PhD Candidacy in the SarcomaLab! We’re inspired by your dedication to transformative #Sarcoma research!