Álvaro Lorente Macías

If you are interested in drug discovery and want to know more about all the approved small molecule kinase inhibitors, their medical indication, pharmacology and original synthesis, check out our last perspective! @ACSBioMed @EdinUni_IGC @BOOMchemistry pubs.acs.org/doi/10.1021/ac…

Interested in using degron tagging to study the function of your favourite protein in genetically engineered mouse models? Check out our review covering recent work in this area: doi.org/10.1242/dmm.05…

🌞Delighted to see our work with @VSmerBarreto @jucaacoco @BOOMchemistry and the Carragher lab on featured in the press today! thetimes.co.uk/article/ai-fin… news.sky.com/story/ai-helps…

💊📢 New paper on #AI for #drugdiscovery in @NatureComms We discovered three senolytics - compounds that kill 'zombie cells' in therapies vs cancer and others #aging doi.org/10.1038/s41467… The most fun collab led by @VSmerBarreto with @jucaacoco lab #compchem #synbio

@BOOMchemistry @JACS_Au Congrats @SYC_Chm @BOOMchemistry excellent work!

Congrats to Shiao for her work @JACS_Au! @BOOMchemistry Excited with the potential of this targeted strategy. pubs.acs.org/doi/10.1021/ja…

See our last work here: pubs.acs.org/doi/10.1021/ac… After years of research, we show "Pd-triggered local chemotherapy" works in vivo and can solve inherent DMPK issues of a chemotherapy drug such as 5FU @ACSBioMed @EdinCRC @EdinUni_IGC @CRUK_BI

Interested to learn more on how molecular organisation, handedness and configuration can aid in synthetic biomaterial design? Check out our recent review here ➡️ pubs.rsc.org/en/content/art… @ChemSocRev @rcontmont, Amanda Ellis, @PalliThordarson and @jonathan_steed

For those interested in #bioorthogonal catalysis, check out this new application just published in @angew_chem in collaboration with @BeckerLabCRTD onlinelibrary.wiley.com/doi/10.1002/an…

Interested in the chemistry behind approved kinase inhibitors? Check out the comprehensive perspective in Journal of Medicinal Chemistry by @BOOMchemistry here: fal.cn/3iYbC

@EdinCRC @EdinUni_IGC Congratulations to all the team involved @BOOMchemistry! Awesome news!!💊

Nuvectis Pharma has licensed rights to develop and commercialize a novel, SRC/YES1 inhibitor discovered at the CRUK Edinburgh Centre @EdinCRC of the University of Edinburgh’s Institute of Genetics and Cancer @EdinUni_IGC. Read more on Yahoo! Finance 👇: finance.yahoo.com/news/nuvectis-…

10 years of research culminates with this work. Our most important contribution to the cancer field. Joint effort from @EdinCRC, @MRC_CRH and @CIB_CSIC!! cancerres.aacrjournals.org/content/early/…

Novel Purine Chemotypes with Activity against Plasmodium falciparum and Trypanosoma cruzi mdpi.com/1173114 @MDPIOpenAccess @ISGLOBALorg @ffarmaciaUGR @genyo_pts @jjdmochon @BOOMchemistry

Synthesis and screening of 6-alkoxy purine analogs as cell type-selective apoptotic inducers in Jurkat cells dlvr.it/S1r9XG

Check out our synthetic strategy to diversify purine libraries for drug discovery. Online on @ChemRxiv doi.org/10.26434/chemr… @BOOMchemistry @jjdmochon

@mariadolores_mg @longlabstanford @Stanford_ChEMH @StanfordPath Enhorabuena!😃

To finish 2020 with great news, I’m thrilled to announce that I’ve awarded the Fundación Alfonso Martin Escudero Postdoctoral Fellowship to work at ⁦@longlabstanford⁩ 🤩⁦@Stanford_ChEMH⁩ ⁦@StanfordPath⁩ fundame.org/becas-de-inves…

@Antonio_DG_ @Stanford @StanfordMed Enhorabuena Antonio!!

I am very glad to have been awarded the Fundación Alfonso Martin Escudero Postdoctoral Fellowship at Fantl Lab ⁦@Stanford⁩ ⁦@StanfordMed⁩!! 🎉🤩Fantastic news to finish 2020!🥳🥳 fundame.org/becas-de-inves…

@ana_aperezl @NatureProtocols Congrats! Great work!!

Happy to see our nice paper published @NatureProtocols great work about making palladium nanosheets inside cancer exosomes for targeting anticancer therapies nature.com/articles/s4159…

A further step in the development of a RIOK2 chemical probe. Congratulations to the @UNC team! @thesgconline @rsc_medchem #darkkinase pubs.rsc.org/en/content/art…