canoebrookbl

2K posts

canoebrookbl

canoebrookbl

@canoebrookbl

Joined Aralık 2020
669 Following776 Followers
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canoebrookbl
canoebrookbl@canoebrookbl·
$qure, $xbi, I believe @WSJ will continue to publish several articles/week jabbing MM and VP with insights from more pro pharma/biotech Susie Wiles and Jim O’ Neill until VP is out and maybe MM as well.
canoebrookbl@canoebrookbl

WSJ really does not like VP. we now know why Dr. Pazdur is in favor of AA. Do MM and VP need to develop neurodegenerative diseases before they understand patients’ needs to access innovative medicines like AMT-130 from $qure? wsj.com/opinion/techno… via @WSJopinion

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pastperformer
pastperformer@pastperformerAU·
@canoebrookbl Did you get anymore slides. Id love to know if it was 100% mta group. Good pick up. This context changes everything.
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canoebrookbl
canoebrookbl@canoebrookbl·
$qure Amt-260 ph1/2 has 2 different groups, one with MTS the other dominant TLE, if the 3/6=50% all cluster in one group, the data actually gave perfect signal. The MTS group is the POC group where the MoA should work but if too many neurons lost in the hippocampus, may not work
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canoebrookbl@canoebrookbl·
$abvx no part 2 release down below $90. Part 2 release back to $68. Love playing this game.
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canoebrookbl
canoebrookbl@canoebrookbl·
$apge bought this in the low mid $30 last year when they had a crazy drop for no obvious reasons. Will see the final price.
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Peter Mantas
Peter Mantas@peter_mantas·
@canoebrookbl Am at the conference where they presented this data. Context matters for and there’s more nuance, but this therapy has the biological activity worth pursing imo.
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canoebrookbl
canoebrookbl@canoebrookbl·
$qure my next major call is amt-130 will be approved by year end 2026 before the new permanent FDA commissioner in office post midterm likely late 2026 or early 2027. This and other reversals will be Kyle Diamantas’ legacy. Target $150 at AA approval, post approval trajectory TBD
BioSpace@biospace

UniQure’s planned third-quarter submission for its Huntington’s disease gene therapy may be a harbinger of a more flexible FDA under acting commissioner Kyle Diamantas—but how long will it last? hubs.li/Q04lTBZ_0

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canoebrookbl
canoebrookbl@canoebrookbl·
$xbi outperformed $smh and AI hardware one day yesterday due to $qure then back to underperform as always!
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canoebrookbl
canoebrookbl@canoebrookbl·
Very weak with all indices responding, $celc $insm $abvx
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canoebrookbl
canoebrookbl@canoebrookbl·
$spcx traders love this volatility! Will be insane once lockups start.
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canoebrookbl@canoebrookbl·
$clpt no position but glad to see some upgrades. Mid 2027 approval seems too standard!
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canoebrookbl
canoebrookbl@canoebrookbl·
$abvx still looking for an opportunity to deploy 90% of my previous put options profits but the stock got stuck below my 10% put option price $106-108. Next shoe to drop 25mg UC induction not approvable by the FDA!
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canoebrookbl
canoebrookbl@canoebrookbl·
$qure Barclays says raising PT to $65 for now but still has a lot more upside potential! Love how analysts play catch up and still sandbag: one analyst has an amt-130 US pricing $$1.7 m.
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canoebrookbl
canoebrookbl@canoebrookbl·
$nktr probably closed my put positions too early given how weak it has been but can’t complain shorted this twice from $60 to low $30 and again from $100+ to high $50.
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canoebrookbl
canoebrookbl@canoebrookbl·
Watching $legn post offering. May initiate a small portion around low to mid $20. Small n in vivo CAR-T gives some hope beyond its legacy drug.
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canoebrookbl
canoebrookbl@canoebrookbl·
I have a portfolio inspired by my daughter, it includes $wdc, $sndk and $atzaf started 12-18 m ago. She also bought $nvda in the low $40 when she was a freshman in college.
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canoebrookbl
canoebrookbl@canoebrookbl·
My next stock recommendation is to buy pullback on $atzaf, Aritzia, a Canadian fashion brand, has stores in every major US mall. Already 4x post trade war but could be a good buy on pullbacks!
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