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Thanks @stevens1lab for the encouragement to post! Click below to learn more about the advocacy logo we made in fall 2019, why we made it, why, now more than ever, we proudly display it and why we hope you display it too! 👇👇
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Cody J. Smith
758 posts
Cody J. Smith
@cssmity
Scientist and Professor at University of Notre Dame; Father and Husband at House of Smith. opinions are my own.
Joined Ekim 2014
378 Following625 Followers
Special thanks to @FChrisBennett and @nachoriko for the wonderfully written primer on our new microglia cannibalism publication. It’s so amazing when such exceptional scientists write about our work!
PLOS Biology@PLOSBiology
Microglia can selectively clear neurons, but what else do they eat? @FChrisBennett & @nachoriko explore a #PLOSBiology study showing that #microglia also cannibalize other microglia, followed by microglial necroptosis Primer: plos.io/4f7sXEs Paper: plos.io/3Aj1JvE
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@micro_glia It's a great question but most the clearance we detected occurred after the cells die.
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@cssmity That's fab work! I'm wondering if you observed any entosis happening as well?
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We are excited that our work describing microglia cannibalism is now officially in press! journals.plos.org/plosbiology/ar…
Stay tuned because we are on to the genetic mechanisms! 😀
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For more information about the study, please see this thread: x.com/cssmity/status…
Cody J. Smith@cssmity
Really excited about our new preprint from the lab about microglia lifespan and cannibalism. Congrats to Hannah Gordon for her hard work! Read more below about the story 👇🧵👇 @ZTSlab biorxiv.org/content/10.110…
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Microglia cannibalism!!!!
PLOS Biology@PLOSBiology
Microglia are considered long lived, but @cssmity &co show that individual embryonic #microglia die within 3 days after clearing neural debris and are cannibalized by existing microglia, paradoxically leading to additional microglial death #PLOSBiology plos.io/3Aj1JvE
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Come join us at Notre Dame!
Katrina Adams@Katrina_L_Adams
Neuroscience faculty job alert! The University of Notre Dame is hiring 5 tenure-track positions in cellular, molecular, or computational neurobiology. Come be my colleague in a welcoming and inclusive environment. Please share! apply.interfolio.com/152596
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Candidates working with various model systems, including non-mammalian models, are encouraged to apply!
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We are seeking researchers who investigate the development, regeneration, and function of the nervous system, as well as the molecular and cellular mechanisms underlying health and disease, detection, and treatment.
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The University of Notre Dame is hiring a cluster of 5 new Assistant Professors in Neuroscience starting this year, focused on cellular, molecular, or computational neurobiology.
Come be a colleague! More information here:
apply.interfolio.com/152596
Please share and retweet!
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I am excited to get this project moving with @stevens1lab to find new microglia modifiers. I am also excited to be part of the larger group of collaborative people that are in the @ChanZuckerberg network!
Chan Zuckerberg Initiative@ChanZuckerberg
💡 Innovation + 👩🏾🔬🧑🏼🔬 Collaboration = 🧠 Increased understanding of the brain Meet 64 interdisciplinary teams working to expand our understanding of neuroscience + find treatments for neurodegenerative diseases czi.co/42K4IqJ
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🎉
NIH Common Fund@NIH_CommonFund
Did you know that the @NIHDirector’s Early Independence Award supports junior #scientists to launch independent careers? Look at how this year’s awardees are “skipping the postdoc” and will pursue their own #biomedical and #BehavioralResearch commonfund.nih.gov/earlyindepende… #NIHHighRisk
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I am excited for our most recent publication led by Jake Brandt (now postdoc with @SD_Ackerman). Jake's work reveals spontaneous activity in DRG glia in the early phases of its assembly. Interestingly to us, a part of the activity was dependent on mechanical channels. 🧵👇
PLOS Biology@PLOSBiology
.@cssmity &co show that satellite #GlialCells in the #PNS display isolated spontaneous Ca2+ transients, sensitive to #mechanosensitive protein #Piezo1, revealing a role for #mechanobiology in the activity of developing neural cells #PLOSBiology plos.io/3t0Ko6w
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@cssmity @LiddelowSA Cody you know how much restraint I had when I RT’d your paper today? Congrats on the new pub!
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brainrnaseq.org
updated look... same data
new QoL improvements:
1. datset downloads
2. orthologs - hello swimmers & squirmers!
3. modern design, still mobile friendly
new APP coming soon - FREE for all - share your RNAseq data with only a spreadsheet and 20 minutes
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I can't believe how satisfying it is to work with research teams like the deep squad assembled by Cody @cssmity (now Jake moved onward to PD with another @3i_inc customer Sarah @SD_Ackerman.) This thread is fantastic and the research is as well. Congrats to the whole team.👇🧵🔬
Cody J. Smith@cssmity
I am excited for our most recent publication led by Jake Brandt (now postdoc with @SD_Ackerman). Jake's work reveals spontaneous activity in DRG glia in the early phases of its assembly. Interestingly to us, a part of the activity was dependent on mechanical channels. 🧵👇
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Finally, Jake made a personal dream come true...we somehow snuck in a Star Wars reference to our research! Next up, legos! media.giphy.com/media/UsmcxQeK…
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Jake's contribution to the lab was so important for our future work! In particular, he introduced calcium imaging to the lab, which opens up our ability to do circuit analysis (coming soon!)!
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