The STRATOS initiative

Happy to present this NEW PAPER of the @stratosinit on 'Regression without regrets: Initial data analysis is a prerequisite for multivariable regression' bmcmedresmethodol.biomedcentral.com/articles/10.11… @f2harrell @MHuebnerPhD #stratosida

Happy to be part of this huge project by TG9 of @stratosinit led by J. Rahnenführer, L McShane and @RiccardoDeBin1, with @StefanMichiels @LaraLusa and others

NEW PAPER Simulation study comparing elastic net vs PCA/PLS for developing clinical prediction models doi.org/10.1002/bimj.2…

NEW Guideline article from Jörg Rahnenführer et al. as part of @stratosinit: Statistical analysis of high-dimensional biomedical data: an introduction to analytical goals, common approaches and challenges bmcmedicine.biomedcentral.com/articles/10.11…

People often ask what it takes to develop a successful (clinical) prediction model Here are TEN important things to avoid

New @stratosinit article: "Issues in Implementing Regression Calibration Analyses" academic.oup.com/aje/advance-ar…

A replication crisis in methodological computational/statistical research ? I have now been working on the topic for 13 years with my group and it is time for a (long) thread. First, let me say this is not about the replication crisis in application fields of statistics. 1/n

@WvanAmsterdam This by @DrPerpo may interest you @stratosinit bmcmedresmethodol.biomedcentral.com/articles/10.11…

1/ New STRATOS @stratosinit article: Are you validating a prediction model developed using Cox proportional hazards? Some key points from our new guidance paper 👇 Ann of Intern Med: acpjournals.org/doi/10.7326/M2… Preprint: medrxiv.org/content/10.110…

NEW PAPER Overview of performance measures for time to event prediction models. Comes with elaborate R and SAS code Journal version (paywall) 👉 doi.org/10.7326/M22-08… Preprint 👉 doi.org/10.1101/2022.0…

#8: Dealing with competing risks when validating a prediction model can be challenging. This paper on behalf of @stratosinit gives guidance and R code Open access 👉 doi.org/10.1136/bmj-20…

Edwin Kipruto and Willi Sauerbrei published the **protocol of their methodological comparison study** (simulation study) in PLOS ONE. Great initiative, very inspiring for our community! pubmed.ncbi.nlm.nih.gov/36191290/ They follow the ADEMP scheme by @tmorris_mrc

@SolomonKurz I would use spline or fractional polynomials. Excellent review by @stratosinit @f2harrell @Georg__Heinze diagnprognres.biomedcentral.com/articles/10.11…

And 2nd day of #RSS2022Conf begins with STRATOS guidance for survival, competing risk and dynamic risk prediction models @RSSMedSection

Are randomised trials answering clear & useful questions? We conducted this review of published trials to find out bmj.com/content/378/bm… @bmj_latest

Perfect summary! 👏thank you @stratosinit

Do you remember when you joined Twitter? I do! #MyTwitterAnniversary

“Exposure to guidelines for observational studies can induce altitude sickness, or stratos fear.” Sayings of Confuseus ⁦@stratosinit⁩ stratos-initiative.org/#:~:text=The%2….

The highlight of my year 😍

ISCB has started with a large presence of STRATOS members. If you are at ISCB make sure you drop by on Thursday at the special STRATOS session