Andrew D Hanson Lab

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Andrew D Hanson Lab

Andrew D Hanson Lab

@ADHansonLab

Andrew Hanson Lab at Univ. Florida/IFAS. Plant & microbe metabolism research, engineering, synthetic biology. Plus PhD/postdoc training & jobs. AMDG+

Gainesville, FL Inscrit le Şubat 2016
561 Abonnements2.4K Abonnés
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Andrew D Hanson Lab
Andrew D Hanson Lab@ADHansonLab·
Mice are sociable & playful. This lovely drawing (birthday present from my wife Claudia) captures the fun of what we call the ‘mouse circus’, a large open pen where they get to play with the equipment (yes, they really do go upside down in the wheel!), with each other, & with us!
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Andrew D Hanson Lab
Andrew D Hanson Lab@ADHansonLab·
@SynBio1 Or, as they used to say in the UK: “You Might as Well Be Hanged for a Sheep as for a Lamb” The context is that the same Draconian punishment was handed out regardless of the animal’s value, so it made sense to steal the more valuable animal.
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Jake Wintermute 🧬/acc
Jake Wintermute 🧬/acc@SynBio1·
A huge incentive to over-hype a new biotechnology is all the miserable bastards who will accuse you of "hype" for even cautious claims Basically if you're going to be even a little optimistic in biotech you might as well go full theranos because the reaction will be similar
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Andrew D Hanson Lab retweeté
Johnathan Napier
Johnathan Napier@JohnathanNapie1·
blog.aspb.org/july-17-plant-… Please join me and the rest of this great panel, discussing how we as a community should not oversell research outputs whilst at the same time demonstrating societal relevance. Lots to cover!
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Andrew D Hanson Lab
Andrew D Hanson Lab@ADHansonLab·
@angus_barrett ‘Ignorant learnedness’ might be seen as a pathology that has always menaced the academic enterprise. It’s when knowledge (or what passes for it) becomes disconnected from reality. Ungrounded, if you like. This also afflicts AI. Big-time.
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angus
angus@angus_barrett·
Beyond ignorance, there is learnedness; beyond learnedness, learned ignorance. But beyond learned ignorance is there ignorant learnedness: abstraction not for truth but for the love of the game? Is the sacred number 3 or 4?
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Andrew D Hanson Lab
Andrew D Hanson Lab@ADHansonLab·
An analogy is getting the skills to build cathedrals. At the start, much about physics & properties of stone was poorly understood. Result: -Some cathedrals collapsed (e.g. Beauvais ⬇️) -Architects & masons learned -Learning took *centuries* -“Stay humble, biodesigners” @SynBio1
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Kenny Workman@kenbwork

do think discourse on engineering biology would benefit from fewer platitudes about the complexity of living systems and more informed optimism about our inevitable path to break down, understand and rebuild organisms

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Michael Mindrum, MD
Michael Mindrum, MD@MichaelMindrum·
“You’ve been lied to” when it comes from a health influencer account should typically be translated into: “I’m going to lie to you”.
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Sebastian S. Cocioba🪄🌷
Sebastian S. Cocioba🪄🌷@ATinyGreenCell·
It's increasingly harder to be not cynical and unkind these days. I catch myself in some loops of anger and disappointment that are very difficult to recover from and return to controlled flight. This place can really strike nerves. What have we built?
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Andrew D Hanson Lab
Andrew D Hanson Lab@ADHansonLab·
@ProfTomEllis This piece reports an interesting initiative but really doesn’t answer its question. Is a straightforward answer at this point “Because in principle we can & the technology might one day be useful”? Also, this passage ⬇️ is boilerplate 🌱 hype, of which we have enough already.
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Sebastian S. Cocioba🪄🌷
Sebastian S. Cocioba🪄🌷@ATinyGreenCell·
I cant wait to never think again. All I ever wanted was to never think again. I love being cripplingly addicted to something that offloads all my cognitive abilities, letting my own skill atrophy for the sake of convenience. Aliens, where you at. This rock is getting real lame.
Roy@im_roy_lee

introducing @cluely. today is the start of a world where you never have to think again. we just killed 9 industries (thread):

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Andrew D Hanson Lab retweeté
Edmar Oliveira-Filho, PhD👨🏻‍🔬
Edmar Oliveira-Filho, PhD👨🏻‍🔬@edmar_oliveiraf·
Excited to share the Hanson Lab’s @ADHansonLab new preprint! We used OrthoRep to evolve Arabidopsis HDH, a short-lived enzyme, selecting variants with up to 20× higher abundance. Mutations boosted lifespan, catalytic efficiency, or inhibitor resistance. 🔗doi.org/10.1101/2025.0…
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Andrew D Hanson Lab
Andrew D Hanson Lab@ADHansonLab·
@thisischristina @SynBio1 I would be tempted to add “…yet” to your last sentence :) Be that as it may, this is a good opportunity to say that I thought the ‘resurrection of a fossil scent’ idea from a few years back was brilliant pro-GMO messaging! I have used it as an example in teaching.
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Christina Agapakis
Christina Agapakis@thisischristina·
@ADHansonLab @SynBio1 I don't think Palantir has been immune to a very similar backlash, with public protests even outside the CEO's house, people agitating very forcefully internally to companies working with them. It just doesn't actually impact their business.
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Jake Wintermute 🧬/acc
Jake Wintermute 🧬/acc@SynBio1·
Biotech spent decades trying to win the public trust with messages about responsibility and caring about patients It didn’t particularly work Big tech is taking a different tack - leaning into “fuck you try and stop us” I’m morbidly curious to see if it will matter
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Andrew D Hanson Lab
Andrew D Hanson Lab@ADHansonLab·
@Manning4USCong @IsaacKing314 @KevinWilsonROC 💯Ice made by refrigeration technology is chemically & physically essentially the same as ice formed during cold weather. Whereas animal muscle tissue & lab-grown ‘meat’ are chemically & physically different & probably always will be.
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Isaac King 🔍
Isaac King 🔍@IsaacKing314·
Came across a neat summary of society's transition to using artificial ice in the mid to late 1800s.
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Andrew D Hanson Lab
Andrew D Hanson Lab@ADHansonLab·
@TomKnightSynBio @srikosuri A key difference btwn CS & biology is that in biology there are far more ‘unknown unknowns’ (let alone ‘known unknowns’. We’ve had big-time biochemistry & mol biol only since WWII. Think of what we now know that we didn’t in e.g. 1960. Were not much nearer full understanding now.
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Tom Knight -- e/🦀🌴
Tom Knight -- e/🦀🌴@TomKnightSynBio·
@srikosuri Particularly interesting to note that AI systems are completely observable and replicable, but we still have problems with understanding. Perhaps that isn't the real problem in understanding biology.
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Sri Kosuri
Sri Kosuri@srikosuri·
It’s kind of interesting, but in some ways AI is making CS much more like biology. We can observe and tweak what it does, but we really don’t know how it’s doing it. A science and engineering discipline rooted in empiricism over theory. I wonder if this trend continues.
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Andrew D Hanson Lab
Andrew D Hanson Lab@ADHansonLab·
See this opening statement for the prosecution ⬇️ (should read “There is a dire need for solutions….” BTW) 💯 some improvements in N use etc are possible. But another big energy use in ag is diesel. How to replace this? Animal traction? Which takes land.. doi.org/10.1007/s42994…
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Elliot Roth || SF
Elliot Roth || SF@ThatMrE·
We consistently let these cute killers in our houses... why? What prompted the human urge to bring wolves and felines inside?
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Jake Wintermute 🧬/acc
Jake Wintermute 🧬/acc@SynBio1·
There's a possible future where we are all healthy, happy in our bodies, and as hot asf
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@SynBio1 @angus_barrett @simon_dell_tog @MichaelMindrum @ATinyGreenCell @ProfTomEllis @MariosGeorgakis @thisischristina