Jake Wintermute 🧬/acc

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Jake Wintermute 🧬/acc

Jake Wintermute 🧬/acc

@SynBio1

Synthetic Biologist - Foundry Theorist - American Wetware - stay humble biodesigners

Cambridge, MA Katılım Haziran 2014
415 Takip Edilen17.1K Takipçiler
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Jake Wintermute 🧬/acc
Jake Wintermute 🧬/acc@SynBio1·
Stop glamorizing the hustle and start glamorizing the mussel
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Ron Alfa
Ron Alfa@Ronalfa·
What if we could use a foundation model to simulate human biology from mouse data? Today, we're sharing Perturb-MARS, a platform for genetics and drug treatment in vivo at SCALE. ... and we HUMANIZE the read-outs using TARIO-2.
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Kumar Garg
Kumar Garg@KumarAGarg·
NEW: I’m so excited to announce the Open Source for Science Fund, with $20M in anchor commitments from @biohub and @wellcometrust. Given the fast progress on AI, building this connective tooling could not be more timely or important. First RFP goes live in a week.
Renaissance Philanthropy@RenPhilanthropy

The AI revolution in science is powered by open source software. Let's fund it. Today we're launching the Open Source for Science Fund @os4science, a new multi-donor philanthropic fund by @RenPhilanthropy, seeded by @biohub and @wellcometrust, with support from @KavliFoundation and Research Software Alliance. 🧵os4science.org/news/open-sour… 1/4

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Jake Wintermute 🧬/acc
@mnovendstern "...which is why your need for spiritual purpose will definitely be met by working for my AI datacenter middleware startup"
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Max Novendstern
Max Novendstern@mnovendstern·
Overheard in Silicon Valley: “Creation as we know it is the aftermath of a catastrophe: language, after Babel, is shattered. The gap between signifier and signified is a cosmological wound. And the entire history of human thought, from Platonic philosophy to Enlightenment science to, ultimately, the scaling of Al, can be read as the project of Tikkun, repair: the painstaking reassembly of those scattered sparks into coherence.”
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American Wetware
American Wetware@americanwetware·
Today's the last day to grab some pixels and make your mark on our shared agar art experiment before we ship it to the bio-printer Tell your grandkids you were there when biology cost 25¢ cheap.americanwetware.com
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Jake Wintermute 🧬/acc
Every truly innovative tech space I've had the privilege to visit always has the most beat up, piece-of-shit couch you've ever seen This is an iron law of technological progress that has no exceptions. To my knowledge, it has never been formally studied
Gaurab Chakrabarti@Gaurab

We couldn't afford a couch when we started Solugen. So I grabbed one from the side of the road. Within a week, all five of us had fleas. Public apology to the original team.

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Ash Jogalekar
Ash Jogalekar@curiouswavefn·
“When I use frontier AI for bioengineering in May 2026, my daily experience is one of frustration. The models are incredibly capable, but frequent and miscalibrated refusals on biological topics make them effectively impossible to use.” This is spot on. My day to day involves building agentic pipelines for biology, chemistry and drug discovery, and model refusals for completely legitimate requests are the bane of my existence. And I hate to say this, but Claude is the worst (and 4.7 is sadly worse than 4.6), followed by GPT and Grok. There needs to be a way for people like me to seamlessly do our work while we guard against the low-probability high-consequence risk of bio and chemical security.
Patrick Boyle — e/🦀@p_maverick_b

x.com/i/article/2050…

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Jake Wintermute 🧬/acc
I've never met I bioproduct I didn't like but I'm not super enthusiastic about this concept
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Stuart Blitz
Stuart Blitz@StuartBlitz·
Peanuts are by far the worst raw nut. Pecans, walnuts, almonds all massively better.
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荻田佑
荻田佑@OTTA58027889·
自宅研究室にて。 研究を開始。 今は酒粕の微生物の研究をしています✨ まずは乳酸菌を分離。 #研究 #酒粕 #乳酸菌
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Jake Wintermute 🧬/acc
@baym There are many different ways to store information, useful for different purposes. Stories are the format for information that you want a human to care about.
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Michael Baym
Michael Baym@baym·
Until you see the story not as artifice but as an information transmission format honed and refined over thousands of years to match our cognition, you are probably not going to come up with something more useful
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Michael Baym
Michael Baym@baym·
While I'm all for rethinking data presentation to be more intuitive and interactive, the reason papers are structured as "stories" is not about marketing or spin but rather that that's the information format we've practiced parsing complex information in from a young age
Zechen Zhang@ZechenZhang5

1/ For nearly 350 years, science has communicated itself through one object: the paper. A linear narrative, frozen as a PDF, written for a human reader. We've come to treat that format as the medium of science itself. It doesn't have to be. It's a historical artifact. 🧵

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Jake Wintermute 🧬/acc
If we de-extincted the dinosaurs as bodyoids with no heads then we could sell dinosaur bones without worrying about the whole jurassic park situation
Tracy Alloway@tracyalloway

NEW ODD LOTS - INSIDE THE MARKET FOR DINOSAUR BONES 🦖 Fossils can sell for millions, just like art, so how are they priced and discovered? @TheStalwart & I speak with Sal Aaron, director at David Aaron Gallery in London and basically a dino bone broker podcasts.apple.com/us/podcast/odd…

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