Oscar Alcalá

@aasthajs He has addressed many of these and emphasizes many of the things he does have trade-offs and you should choose your own risks. e.g. he says he is vegetarian by personal philosophy, not for optimization.

I used to be a Bryan Johnson fan. I’ve changed my mind. Here’s why: - Once you understand even basic biophysics & circadian biology, I don’t see how you can listen to him. - He gets 0-10 minutes of sunlight. Doesn’t understand how life evolved with it for 4.6bn years, how avoiding sunlight is as bad as smoking, the power of light therapy. I get 6-8 hrs of sun everyday. - Doesn’t talk about the impact of LEDs and artificial lights on health. - Thinks his diet is the best in the world. Can’t possibly be true with no fish, and no mention of local food. - Crazy number of supplements, dubious at best. Sure, he’s a good inspiration for people but pulling on the wrong levers. No sunlight is the biggie for me. More on why:

La gente que aprieta el botón azul son la razón por la que no podemos tener cosas buenas. Toman la opción que creen los hace moralmente superiores cuando en realidad están tomando la única decisión que introduce riesgo y pone vidas en peligro.

@bryan_johnson Coffee is so bipolar. For every pro it seems to have a con.

Surprising new findings about coffee: you are drinking coffee for the gut bugs that run your brain. > coffee affects the gut which then affects your brain > it's the coffee bean, not the caffeine, doing most of the work > polyphenols feed gut microbes, microbes send chemical messages, brain responds > both coffees lowered inflammation, caffeine drove it further down (IL6, IL10) > decaf raised systemic inflammation markers (hs-CRP, TNF-alpha) > decaf uniquely fed the protective gut microbes > caffeine blocked those gains by pushing food through too fast for the Clostridia bacteria to finish their work > at baseline, coffee drinkers sat in the bottom 25 to 30 percent for protective gut metabolites compared to non-drinkers > coffee lifted mood, cut depression and stress > caffeine specifically lowered anxiety. > the stress hormone story people tell about coffee does not hold up, cortisol did not budge Study details: 62 people, 14-day coffee washout, then 21 days randomized double-blind to caffeinated or decaf. They measured gut bacteria, stool and urine chemistry, cognition, mood, blood inflammation, and cortisol. What to do Caffeinated in the morning for focus and lower anxiety. Decaf in the evening for memory and gut. One cup 6 hours before bed still acts like half a cup at bedtime. Less is better than more either way. The takeaway You are drinking coffee for the bugs that run your brain.

@JessNoFace TLDR: We were projected to get the 5th best rusher in the draft, we got the 4th.

but honestly I don’t even know what I expected at this point. I stopped knowing who people were after Ioane was off the board

25 year old rookie 😭 going to be signing his next contract with a nursing home

@5ARSociety What's the use case? counter-balancing the effects of systemic 5AR blockers?

@elonmusk CLI when?

Grok

@chargers @Tljefferson23 Finally!

unc is BACK

@SleeperHQ so...about the same as most of the season

Current state of the Chargers O-Line 😭

@JessNoFace @AdamSchefter "Future Wes Welker" they said that one preseason.

@AdamSchefter chargers legend michael bandy

Broncos re-signed free-agent WR Michael Bandy.

Mood:

@BB_Chargers If McDaniel thinks he still has gas left in the tank and use for him, yes.

Let's say Tyreek Hill is willing to sign a one-year deal for $10 million or less. Would you do it?

@Tljefferson23 You and the rest of the team will get your turn, bro. Keep up the good work.

Craving the feeling the Seahawks are feeling right now . Knowing you’ve won the bowl. I actually need it so bad 💍.

Estaba hablando con mis primos de los anuncios del Super Bowl y les conté sobre este que iba a sacar Anthropic burlándose de ChatGPT. Nadie sabía que era Anthropic ni Claude. La ventana de oportunidad de la IA sigue siendo enorme. Allá afuera aún no saben lo que viene.

Esta es la versión moderna de Apple vs Microsoft. Anthropic está aprendiendo a hacer marketing y trabajar en la experiencia de usuario. OpenAI está jugando por la adopción en masa. (Mientras tanto, Google está jugando con resistol en una esquina)

Lo que prometió el de ventas / Lo que entregamos.

Es posible que estemos viendo en tiempo real el inicio de la singularidad. Ya era hora.

The number of pushups won’t matter until you change how you see yourself. If you see yourself as a lazy person, you’ll always quit. If you start to change who you are, and become someone who trains and doesn’t give up, that’s what matters. Identity change requires action. It’s the proof for your mind that you are someone different than it thinks right now. So start small. Prove to yourself that you’re someone who does 10 pushups and 10 squats right when you wake up every day. You can grow from there, but first we have to change who you think you are.

@WallStreetMav @alphafox Ah, the Vicky Mendoza diagonal.

How the heck is she single??

Hey Apple, más te vale no arruinar el casting de mi homie, Dalinar.

Están a tiempo de leer The Stormlight Archive para que puedan ser pretenciosos con sus conocidos y decir que conocían los libros antes de que fuera famosos y que son mejores que las películas. Altamente recomendados.