Chauhan Lab

Our new MRI-based study on venous thrombus resolution, published in RPTH (doi.org/10.1016/j.rpth…), was highlighted by Hemostasis Today (hemostasistoday.com/insight/thromb…). We propose novel unified metrics to quantify thrombus resolution.

Our review in Blood (doi.org/10.1182/blood.…) explores how targeting metabolic pathways opens new possibilities for safer DVT therapies. Honored to see it recognized by Prof. Flora Peyvandi in Hemostasis Today. hemostasistoday.com/science/metabo…

Delighted to share our latest article in @BloodAdvances demonstrating imbalanced VWF-ADAMTS13 axis worsen stroke outcomes following respiratory infection @RakeshPatel2083 @aditijain_5 @ironmonger012 @DrSaurabhSaini @joshuamuia @PrajwalGurung @Ivan19174090 ashpublications.org/bloodadvances/…

Congratulations to Rakesh Patel, PhD, postdoc in @ChauhanLab, for his @AHA_Research fellowship. Dr. Patel will build on his work examining the connections between Von Willebrand Factor, respiratory tract infections, and stroke. internalmedicineiowa.org/2024/02/15/pat…

A pair of University of Iowa researchers presented their research at the International Stroke Conference in Phoenix this week! They studied several potential cerebroprotective treatments and are using AI to help analyze data. #ISC24 #ISC24Midwest @IntMedatIowa @UIowaResearch

The results of our collaborative study - Stroke Preclinical Assessment Network (SPAN1) are now out in @ScienceTM. A big kudos to our team @RakeshPatel2083 and @MKumskova, alongside Dr. Chauhan and @EnriqueLeira leading as PI's. science.org/doi/10.1126/sc…

Delighted to share that our review article discussing the role of metabolic enzymes in regulating platelet function and thrombosis is now online on #CardiovascularResearch. @Gaganflora @manasbiotech @MadanGhatge @escardio @IntMedatIowa @CVR_TomaszGuzik academic.oup.com/cardiovascres/…

Thank you @ASHClinicalNews for featuring our paper in the Literature Scan of August issue - Bleeding Symptoms in Patients With #EhlersDanlosSyndrome Range From Mild to Life-Threatening ashpublications.org/ashclinicalnew… @ChauhanLab @janice_staber @IowaMSTP @Gaganflora

#EhlersDanlosSyndrome patients are at high risk of #bleeding. Recent findings from our lab in @JTHjournal identify the severity and occurance of hemorrhage in EDS patients. @MKumskova @Gaganflora @janice_staber @IowaMSTP @ChauhanLab sciencedirect.com/science/articl…

Happy to share the print version of our study demonstrating the role of MCUb in platelet activation and thrombosis is out in @JTHjournal. @MadanGhatge @manasbiotech @Gaganflora @MKumskova @Aditijain_5 @RakeshPatel2083 Zhihong Lin and Yuriy Usachev. sciencedirect.com/science/articl…

Delighted to share the final version of our article on the role of neutrophil integrin α9β1 as thrombo-inflammation regulator after stroke in obese-hyperglycemic mice. @RakeshPatel2083 @Nirav_Dhanesha @MadanGhatge @prakashdp1 @MKumskova @EnriqueLeira ahajournals.org/doi/10.1161/ST….

”The University of Iowa stands at the forefront of cerebrovascular research.” See how @uiowa researchers are working to advance stroke care by testing uric acid as a treatment method. spr.ly/6013OoJt3 #StrokeMonth

Excellent job by @MKumskova in presenting her findings on Ehlers-Danlos syndrome at #VascularDiscovery2023. Many congratulations to her on receiving a travel grant award for early career investigator. @IntMedatIowa @uiowa

Excited to share that our latest research on the role of the pyruvate dehydrogenase kinases (PDK2 and PDK4) in #platelets is now out in @BloodAdvances. Huge thanks to everyone involved. @Gaganflora @manasbiotech @MadanGhatge @MKumskova @RakeshPatel2083 ashpublications.org/bloodadvances/…

Congratulations to @uiowa - SPAN Team! @Nirav_Dhanesha @RakeshPatel2083 @MKumskova @EnriqueLeira @angelchamorro1 medcom.uiowa.edu/theloop/news/u…

UI-led therapy is best for protecting brain tissue during stroke treatment medcom.uiowa.edu/theloop/news

@angelchamorro1 Congratulations to the University of Iowa team, Dr Leira, Dr. Chauhan and his lab members Nirav, Rakesh, Mariia, Brijesh and Dr. Dan Thedens.

Span results at last: the winner is URIC ACID!!!!! The neuroprotection v.2 is declared open

Congratulations to @uiowa - SPAN Team! Final Result: Uric acid (16mg/kg) given intravenously at the time of reperfusion was found to be cerebroprotective in a multi-center pre clinical trial (SPAN) @Nirav_Dhanesha @RakeshPatel2083 @MKumskova @EnriqueLeira @angelchamorro1

Great presentation by our postdoc @RakeshPatel2083 at #ISC23 to discuss the role of neutrophil-specific integrin alpha9 in improving stroke outcome in obesity induced hyperglycemic mice. @uiowa @IntMedatIowa

Many congratulations to @manasbiotech on receiving a Travel Grant Award for Early career investigators at #AHA22 @atvbahajournals @American_Heart