Patient 023 💉

A few years ago I lost 130 lbs doing keto. Got into the best shape of my life. People told me I inspired them. Then COVID hit. The weight came back. Then the motivation left. Then I deleted social media, stopped talking to people, and just... hid. I've been living a fake life ever since. In situations I don't want for myself. Sick of it. I tried Ozempic last year — worked for 2 months, then the appetite suppression disappeared and it just made me feel awful. Did carnivore for 6 weeks this year. Still didn't lose weight. I just need a win. I'm hoping retatrutide gets me on the right track and gives me my life back. I know it's a tool. I know I need to meal prep and train to see the full potential. But when you're big, you need to see consistent loss on the scale to stay motivated. The second it stops, I give up and go back to old habits. Every time.

@DelixLabs @HackneyManLee Thank you 🙏🏿

@RetaDiary @HackneyManLee this is the right framing. the food relationship piece is what most peptide takes miss — GLP-1s reduce food noise but they don't rebuild your defaults. nutritionist + the meds during the window of low cravings is when the rewiring actually sticks. rooting for you

Week 4, still at 0.5mg. The dreams on this drug are no joke. Last night I literally got stabbed by my ex in a dream while my wife watched. Vivid doesn't even begin to cover it. Anyone else on GLP-1s getting the cinema-quality dreams? #RetaDiaries #GLP1 #ClinicalTrial #Dreams

I started at 330 lbs. On 0.5mg of retatrutide I'm eating 1500-1700 calories a day without trying. No hunger. No struggle. Just... content. For someone my size, that's remarkable. So far this drug is different. #RetaDiaries #GLP1 #ClinicalTrial #Retatrutide

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@HackneyManLee Yes sir

@RetaDiary Is 12mg the max dosage you'll eventually go up to?

@DelixLabs @HackneyManLee Yup, I understand it’s a tool and I also need to repair my relationship with food. A great part of the trial is I get a nutritionist to help. Appreciate you sharing this knowledge.

@RetaDiary @HackneyManLee fair concern. tachyphylaxis on GIP/GLP-1 axis is real but reta has triple-agonist activity (GLP-1/GIP/glucagon) so escape mechanisms are different than ozempic. 2 yr horizon you'll likely see appetite drift back — the play is cementing the habits before that hits

@HackneyManLee Interesting. I have to be on Reta for 2 years so I’m hoping the suppression doesn’t eventually disappear like ozempic and tirzepatide.

@RetaDiary I had seen a lot of chatter about Reta and was curious. I was at a point where the appetite suppression on 5mg of tirzepatide was waning so I was considering going up to 7.5mg, but opted to try Reta instead

@HackneyManLee Curious to know what made you switch? I did ozempic last year but the appetite suppression wasn’t there for me.

@RetaDiary 2 weeks at 2mg, then 4 weeks at 4mg. I was on 5mg of tirzepatide for about 4mths then switched to Reta right away, hence why I started at 2mg.

@HackneyManLee Yeah, that’s what I’m eventually supposed to go to. How long did it take you to go from a starter dose to 4mg? I believe I’m getting 1mg next week from the clinic.

@RetaDiary My original plan was to stay on 4mg for as long as I'm seeing results and then go to 6mg. But I haven't felt any major appetite suppression or weight loss so far, and I feel I should be okay given the earlier trial group went from 4>8mg

@HackneyManLee I’m interested to know as well. I always find it to happen on shot day.

@RetaDiary I have actually had a few weird dreams the last few days now that you mention it. I titrated up from 4mg to 8mg today. Will be interesting to see what my observations are at this dosage.

@tropicaltrader7 Good, lol. I wouldn’t wish this on anyone haha

@RetaDiary Lol no

Shot 4 of 4. Last starter dose in the books. Looking forward to moving up next week. Gonna go back to injecting above the belly button this time — tried below last week and the suppression wasn't there. Some things you just gotta figure out as you go.

@johntreebeard20 @fitcapdefi Appreciate that. I’m trying to go slow and keep it boring. Shot 4 tomorrow and I’m still at 0.5mg, so just tracking everything honestly for now.

@RetaDiary @fitcapdefi My advice is go slow. 7 weeks in I’m titrated up to 2.5mg and have lost 30 lbs. Eat well and exercise and it will change your life

daily appreciation post for retatrutide

@SpursFanVIP That makes sense. The weekly rhythm is the weird part. Some days feel quiet and then I start wondering if I’m just overthinking every signal.

@RetaDiary Remember it’s life is only 6 days so that’s normal

Shot #3 goes in today. Still on 0.5mg — the starter dose feels almost laughably small. But something is already different. Appetite isn't gone. Just quieter. Logging everything. #Retatrutide #RetaDiaries

@TheCryptoDaddi Yeah I’m trying not to add too many variables at once. Want to know what is actually coming from the trial med versus everything else I’m changing.

@RetaDiary Yep I’m at same dose of Mag but no Ltheanine though I do know it’s helpful! Maybe I’ll add that in 🦾

If you’re taking Retatrutide, here are a few suggestions: - Start low. Many people take 5-8 mg of Reta because that’s what studies go up to (sometimes 10-12 mg). Unless you are very overweight and need that amount, you shouldn’t use it. - Eat clean and include carbs. This is especially important if you’re pairing Reta with a peptide like MOTS-c. Your body needs carbs. I personally aim for 200 g daily. - If you’re struggling with sleep on Reta, get 10k+ steps daily. Consider pairing with DSIP (Delta Sleep Inhibitor Peptide), magnesium glycinate, and 0.5-1 mg of melatonin. This has been my nighttime routine and works great. - Most importantly, work out. Reta works well on its own, but its effects are multiplied with a good resistance training program. - Reta raises your resting heart rate by about 5-10bpm. Avoid heavy amounts of caffeine and take about 5-10 minutes a day to focus on your breathing. Sounds ridiculous but it will help you adjust throughout the day when you feel anxiety, I’m sure others have posted similar suggestions, but these are the things that have helped me on my journey.

@johntreebeard20 @fitcapdefi That’s good to hear. I’m still trying to be patient with 0.5mg and not turn every tiny change into a big conclusion.

@RetaDiary @fitcapdefi You can get good results at lower doses

@BigPeptideGuy Exactly why I started posting. I wanted the boring middle, not just the magic before and after. Shot 4 tomorrow.

@RetaDiaries Real phase 3 diaries are way more useful than another before and after ad

This is a retatrutide injection pen. Not a promo. Not a paid post. This is my actual Phase 3 clinical trial pen. Retatrutide isn't on the market. I'm one of the patients in the trial. Starting dose: 0.5mg. I'm going to document everything — the doses, the side effects, the weight, the data. Unfiltered. Follow if you want the real story from inside the trial.

@johntreebeard20 @fitcapdefi That’s what I’m hoping. Still at 0.5mg so I’m trying not to get ahead of myself. Protein is the one thing I keep coming back to.

@RetaDiary @fitcapdefi Feels great right? I’ve been successful prioritizing protein in my diet too

Drinking bad. @WHOOP