David Stout

3.3K posts

David Stout

David Stout

@bio_value

Biotechnology connoisseur.

CA शामिल हुए Aralık 2010
1.1K फ़ॉलोइंग313 फ़ॉलोवर्स
Tabbs
Tabbs@DoctorTabby·
@bio_value @RichardHanania The answer is no. Because people like me literally stop the ones that shit in the fucking street from coming here.
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Richard Hanania
Richard Hanania@RichardHanania·
Indians are literally everything conservatives say they want in citizens. But they're dark skinned. So you basically get a perfect experiment. Are people who complain about immigration just racist? It turns out, the answer is yes.
John J.S. Soriano@JohnJSSoriano

94% of Indian immigrants with children are stably married, compared to 66% of white Americans. That is something they are doing right, not something you control away! This guy is holding it against Indians that their children grow up in stable families. Very conservative!

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David Stout
David Stout@bio_value·
@BEisenhart Who thinks a mortgage upon purchase shouldn't be more than 20% of *net* take home pay? Even Dave Ramsey would find that conservative lol
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Ben Eisenhart
Ben Eisenhart@BEisenhart·
This is the mortgage on a $500k home in a newer suburban area in Omaha with $100k down, including taxes and insurance. It is about as low as you will find in the Elkhorn/Gretna/Bennington, NE area. If you are in the camp that your mortgage shouldn’t be more than 20% of your net take-home pay, your household income needs to be at least $19k a month. Not a lot of people hit that, so are we talking about 30-40% of your net take-home pay? Throw in childcare, and Houston, we have a problem. Not sustainable.
Ben Eisenhart tweet media
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David Stout
David Stout@bio_value·
@DoctorTabby @RichardHanania Have you ever seen an Indian shit in the street or have a poop festival in the USA? Assuming the answer is no, I ask the question that you asked back to you.
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Tabbs
Tabbs@DoctorTabby·
@RichardHanania Indians shit in the fucking street and have poop festivals. Are you fucking retarded?
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David Stout
David Stout@bio_value·
@JulieChangRE Far as I know that’s a particularly nice part of Scottsdale Also, for 6 months of the year, the weather is close to perfect
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Adam Feuerstein ✡️
Adam Feuerstein ✡️@adamfeuerstein·
I think $ERAS made a big mistake in deciding to share a ton of data in a very long, after-hours call. Investor relations mistake. The company should waited a day and done this in the morning.
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David Stout
David Stout@bio_value·
@indexnforgetit @AmericaMaximal There's always somebody with this midwit low value take Sure, let's move from the region where somebody has family, friends, a life, and a career, just to afford a place to live. And if they choose not to, they apparently have a "spending problem"...
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TheWealthCoach
TheWealthCoach@indexnforgetit·
@AmericaMaximal Here's a crazy concept you can't afford a coastal place on 96k/yr Move
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David Stout
David Stout@bio_value·
@lalovestrump It’s incredibly good. Tastes like actual Hawaiian poke
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David Stout
David Stout@bio_value·
@ant_trading1 @ToddsTradeEasy $400/mo insurance for a 2023 civic is insane. I’m sure you can shop around and find better. Unless she has multiple DUIs or something
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Ant
Ant@ant_trading1·
@ToddsTradeEasy my girlfriend says “she needs something reliable” My car is paid off and my insurance is 132 a month Her car is a 2023 Civic and she pays $350 plus $400 insurance
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Ant
Ant@ant_trading1·
Me and my girlfriend make $6,000 a month How are we supposed to pay $2,250 rent $1,040 Car + 2 Insurances $50 Wifi $100 Phone bill $200 groceries $1000 Credit card bill Whatever extra stuff we need. Life’s hard
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David Stout
David Stout@bio_value·
@DonroeDoctrine1 @GenZMultifamily Youre aware that OC homes cost $400k not all that long ago. Pre-COVID it was mostly a pretty affordable place Speaking of, who mentioned OC? I didn’t. I said Southern California
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Nick
Nick@DonroeDoctrine1·
@bio_value @GenZMultifamily OC is one of the long time hottest economies in the country with the best weather around. You are going to have to build a ton of homes to overcome out of state swarms that will snatch them up before they fall to $750k.
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GenZ Multi Family
GenZ Multi Family@GenZMultifamily·
"We need more affordable starter homes!" Meanwhile, there's thousands of great homes just like this for sale.
GenZ Multi Family tweet media
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David Stout
David Stout@bio_value·
@StevenMeyerUX @GenZMultifamily As if the housing market over the past 15 years has been driven by “supply and demand” And yeah… it’s good for a society for people to generally stay close to their hometowns and build communities
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Steven Meyer
Steven Meyer@StevenMeyerUX·
People don’t want affordable housing. They want a million dollar home in the highly desirable city they grew up in to go for $250k. So basically, they want to ignore supply and demand. It is not a realistic outcome that can be solved by politicians who all claim they are going to solve it.
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David Stout
David Stout@bio_value·
@GenZMultifamily @DonroeDoctrine1 Southern California is an area of 20 million people. $250k maybe not, but it’s not unreasonable to expect $750k starter homes When home price appreciate has been magnitudes above inflation, and has been driven by exogenous factors, people are right to complain.
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GenZ Multi Family
GenZ Multi Family@GenZMultifamily·
@DonroeDoctrine1 That would be a totally valid statement, the problem is they keep bitching about having no $250k starter homes in Southern California.
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David Stout
David Stout@bio_value·
@stansergiu_ @ThinkAppraiser Assuming they are PAs or nurses and not physicians… They might be really young ie: late 20s and only have 2-3 years experience They might have most savings in 401k They might not want to blow every penny of savings Plenty of good explanations here
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Sergiu Stan
Sergiu Stan@stansergiu_·
@ThinkAppraiser If they barely got 50-60k down and both work in medical field... that's a skill issue
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think like a real estate appraiser
Story time: did a job today for a young couple refinancing their house in OC They paid $1.1M 2 years ago only putting down 5% on the loan They’re refinancing to get rid of PMI Which will save them over $1000/month off their payment Both husband and wife work full time to barely cover the mortgage Both are in the medical field and make good money They had zero family help and were competing against all cash offers and 50% down payments from other buyer’s family members They finally got an offer accepted after months of looking and battling many other buyers Loan officer said you can afford the payments but the down payment is your challenge, so they decided to only put down 5% Their down payment came from being early in Tesla stock and early in Bitcoin They’re stressed out like crazy and can’t believe this is what it takes just to own a home without any help from family. So to recap: They needed to hit the lotto with Tesla and Bitcoin to have enough to put down 5% on the cheapest house in the area to get the pleasure of having a $9,300/mortgage PITI HOLY MOLY 😮‍💨
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David Stout
David Stout@bio_value·
@LPessa7654 @a_a_free This is also wrong. The 6-month OS for RVMD + mGnP was 90% (83% is mono-tx darax)
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personofinterest
personofinterest@LPessa7654·
@bio_value @a_a_free oh and just to make it clear, at 6 months $IMRX beats $RVMD with 94% survival x 83% survival and far less toxicity....I wonder how it would look like at 12 months
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A.A
A.A@a_a_free·
$RVMD vs $ERAS will be one of the most heated discussion if ERAS data will be better. We will see funny discussion in this context. Still believe $RVMD will be the leader here but $ERAS can be a winner too after $RVMD.
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David Stout
David Stout@bio_value·
@LPessa7654 @a_a_free This graph is wrong. The confirmed ORR for darax + chemo was 58% and DCR was 90% at AACR
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personofinterest
personofinterest@LPessa7654·
@bio_value @a_a_free $imrx x $rvmd in 1L patients, who is more data transparent? and why $rvmd has a 13.7 mo follow up in 1L but only released 6 mo survival rates? how bad is the curve??
personofinterest tweet media
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Andy
Andy@AsyncAndy·
@evanwch Normally I’d totally agree with you but this case does actually pose a real national security risk.
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David Stout
David Stout@bio_value·
@LPessa7654 @a_a_free One company has randomized survival data and tons of positive data on ORR, PFS, and OS One company has open-label combo data showing some nice OS, but has minimal single-agent activity, and minimal activity on other efficacy parameters Hope that helps
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personofinterest
personofinterest@LPessa7654·
@a_a_free I don't get it, $ERAS is worth $7B in phase 1 and $RVMD +$30B while $IMRX entering phase 3 with better survival and toxicity results than $RVMD is being traded at $ 350 m with $ 220 m in cash. This is the most asymmetric risk x upside I've ever seen in biotech...
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Proximal AI
Proximal AI@ProximalAI·
@3Sentinel4 @ThinkAppraiser To buy that lot if it was empty and build a 900 sq ft house would probably be $650K+ Cost of land, labor and regulations hold up prices
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think like a real estate appraiser
Watts is a ROUGH area. Rough. Rough. Check out these homes prices Prices are not going down any time soon.
think like a real estate appraiser tweet media
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Rose TheArtist
Rose TheArtist@rosethaaartist·
You can make 80k a year with good credit and not afford a 400k home. That has never been a thing ever in America.
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David Stout
David Stout@bio_value·
@ULuvenD @thiquegyal @rosethaaartist There's always somebody who posts this low value midwit response Sure, let's leave my entire family (several generations worth), my friends, my professional network, just to go buy cheap real estate. Sounds like a great idea!
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