Devlin Lab

Check out our paper published today in @PNASNews! Gut microbiome–produced bile acid metabolite lengthens the circadian period in host intestinal cells | PNAS pnas.org/doi/10.1073/pn…

The Devlin lab is seeking a new postdoctoral researcher to join our group (start date between now and Spring 2026). Chemists and biologists interested in how gut bacteria affect human health are encouraged to apply. More information on our lab website devlin.hms.harvard.edu/contact/.

We just published a paper in @mSphereJ about bacterial contributions to the progression of primary sclerosing cholangitis (PSC), a chronic liver disease whose only current treatment is liver transplant. Check it out below! journals.asm.org/doi/10.1128/ms…

Check out our new review article in @NatImmunol about the role of gut microbial metabolites in the T cell lifecycle! nature.com/articles/s4159…

Check out our new paper published @cellhostmicrobe! Lithocholic acid (LCA) is a metabolic toxin decreased by bariatric surgery. Taurodeoxycholic acid, which is increased by surgery, inhibits LCA production by microbes and has metabolic benefits. authors.elsevier.com/a/1jTSj6t8JEqo……

We're very excited to share that our paper on the 21-dehydroxylation of steroids is online in @CellCellPress today! Read how flatulence drives bacterial production of allopregnanolone, an FDA-approved drug for postpartum depression. Full-text here: authors.elsevier.com/a/1j8j7L7PXqQmM

We are super excited that our review on the sulfated metabolome is online in @nchembio today! Led by Gabriel and Snehal in the lab. Check it out! nature.com/articles/s4158…

Our lab provides a welcoming and supportive environment in which to do science, and Prof. Devlin supports postdocs interested in a range of career trajectories. Come join us! (2/2)

Please share! The Devlin lab is looking for postdoc fellows. Candidates with experience in either 1) tissue culture & cell-based assay development or 2) analytical chemistry, biochem, or organic chem. are encouraged to visit our lab website & email Prof. Devlin directly. (1/2)

Snehal initiated the collaboration between @DevlinLab and @BWHSurgMetab , organized my interview two years ago, and has been an excellent collaborator for the past two years. Best wishes on her new journey!

Earlier this week we said ~see you later~ to one of the OG Devlin lab postdocs, Snehal Chaudhari, as she embarks on her journey as an Assistant Professor at @UWBiochem! We are so proud of her but we’ll miss her big time 😭

On Monday July 24, the Keio University Human Biology-Microbiome-Quantum Research Center (WPI-Bio2Q) held its Gut Microbiome Seminar. “Causal links between human gut bacterial metabolites and host functions” Sloan Devlin, Ph.D. Associate Professor, Harvard Medical School, USA

Long overdue, but our first grad student @microbe_megan just defended her thesis in May!🤩 She also just gave an AMAZING talk at #bbm2023 @BostonBacteria on her thesis work. 🎉 What an exciting couple of months!

Oh btw I defended my dissertation last week? Here’s me being a silly goose trying to open the bottle of champagne

We’re at the #MITmicrobiome Symposium today! Two of us are presenting posters today: Gabriel (poster 14) and Megan @microbe_megan (poster 13). Come check them out!

Save the date! Sloan Devlin (@DevlinLab) at @harvardmed is #ASBMBDeuel's Journal of Clinical Investigation (@jclinicalinvest) Lecturer. Register for the conference to attend her talk, "Bacterial modification of bile acids alters host physiology," on 3/ 8: asbmb.org/meetings-event….

Check out our fearless leader on the @MicrobiGals podcast this week!!!!

Excited to be part of this ACS Chem Biol virtual event next Tuesday highlighting young #chembio investigators — registration is free! go.acs.org/28s @FFriscourt @IfthihaMohideen @DevlinLab @HuangMia @WangXiaoLab @EllenSletten @Linlab_ZJU & Samira Musah & Kabirul Islam

Gut bacterial modifications characterized so far involve hydrolytic & reductive pathways. @DevlinLab & colleagues have discovered a mechanism by which gut bacteria sulfonate steroidal metabolites that can modulate immune cell trafficking @NatureMicrobiol nature.com/articles/s4156…

We’re excited to share our latest paper in @ScienceAdvances led by Snehal in our lab and Darrik Li in Raymond Chung’s lab @MGHLiverCenter! Check it out! science.org/doi/10.1126/sc…