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Promoting Antimicrobial stewardship at SWB youtu.be/rqgKZG5wPDM #AntibioticGuardian #AntibioticResistance #spreadawarenessstopresistance #KeepAntibioticsWorking #WAAW2021
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SWB Guardians of Resistance
253 posts
SWB Guardians of Resistance
@SwbGuardians
Antimicrobial stewardship team, Sandwell and West Birmingham NHS Trust. All views are of our own.
Bergabung Kasım 2021
245 Mengikuti147 Pengikut
SWB Guardians of Resistance me-retweet
Exemplar ITU consultant sets the standard truly the best 👍👏👏
Keeps watch above the elbow, passing the test!"
complying with BBE policy @SWBHnhs @IpcSwbh @melrobe08536915 @MrDShakespeare1 @SwbGuardians
English
SWB Guardians of Resistance me-retweet
Echinocandin Vs fluconazole step down in patients with candida glabrata candidaemia?
🆕💫Retrospective,single-centre cohort study #JAC
No significant difference in treatment duration,incidence of persistent candidaemia or 30d clinical failure between 2 gps
academic.oup.com/jac/advance-ar…
English
SWB Guardians of Resistance me-retweet
Tazobactam does not inhibit AmpC-mediated hydrolysis of TOL and demonstrates poor binding affinity for both wild-type and mutant AmpC enzymes
🆕💫 #AAC
Restoring ceftolozane susceptibility: a role for diazabicyclooctane β-lactamase inhibitors #idxposts
journals.asm.org/doi/10.1128/aa…
English
SWB Guardians of Resistance me-retweet
**Starting 2025 with a key update:
The new ATS/CDC/ERS/IDSA guidelines on treating drug-susceptible and drug-resistant tuberculosis (TB) are out!
What do you think about these changes? How will they shape clinical practice moving forward?**
#idxposts
Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟@ABsteward
🆕🔥Just published 🔥🆕 Updates on the Treatment of Drug-Susceptible and Drug-Resistant Tuberculosis(TB) An Official @atscommunity @CDCgov @IDSAInfo @EuroRespSoc Clinical Practice Guideline Thanks @Inox94 #idxposts atsjournals.org/doi/full/10.11…
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SWB Guardians of Resistance me-retweet
In the context of emergence of cefiderocol resistance and of limited therapeutic options, the in vitro determination of cefiderocol susceptibility with a robust method is essential!
🆕💫Cefiderocol susceptibility testing: the challenge of disc diffusion
clinicalmicrobiologyandinfection.com/article/S1198-…
English
SWB Guardians of Resistance me-retweet
🔹Penicillin Binding Proteins🔹
⚡ Enterococci are relatively resistant to cephalosporins since Cps act through PBP2/3 while Enterococci use PBP4/5
⚡ MRSA are resistant to anti-Staph Penicillins by altering PBP2 ➡️ PBP2a through mecA/C
#MedTwitter
#IDTwitter
#JustIDThings
DrGeethu Joe@GeethuJoe
Penicillin binding proteins
English
SWB Guardians of Resistance me-retweet
AmpC-producing Enterobacterales:
Expected phenotypes for wild-type strains and in cases of AmpC derepression and ESBL production
doi.org/10.3390/pharma…
English
SWB Guardians of Resistance me-retweet
🫀New Dukes criteria for Infective endocarditis
✅ E. faecalis is classified as a typical cause of IE
✅Inclusion of cardiac CT/PET for IE diagnosis
✅Surgical inspection of cardiac valve included as major clinical criteria
English
SWB Guardians of Resistance me-retweet
Day 4 #WAAW2024
50% all antibiotic prescriptions are unecessary.
Time to hold prescribers accountable:
[RE] EDUCATE - yourself & remember what antibiotics are used for
ADVOCATE - for proper use
ACT NOW - be accountable change your role from driving to mitigating this crisis
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SWB Guardians of Resistance me-retweet
Blood cultures are 🔑 to detecting bloodstream infections & fighting #sepsis; we need them to optimize antibiotic prescribing. Let’s improve the blood culture pathway for better patient outcomes. #AntimicrobialResistance #AMR #AntibioticGuardian #KeepAntibioticsWorking #WAAW
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#WAAW2024
#AntimicrobialResistance
Promoting good antibiotics prescribing
To use antibiotics prudently and protect their effectiveness for future
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SWB Guardians of Resistance me-retweet
This week is World AMR Awareness Week. We can all play a part in the fight against #AntimicrobialResistance. If you're prescribed antibiotics:
Don't save them for later 💊
Take them as directed 👩⚕️
Don't take them for colds and flu 🚫
#WAAW
GIF
English
SWB Guardians of Resistance me-retweet
SWB Guardians of Resistance me-retweet
Fantastic 🆕️🔥Review by @SIDPharm 🌟 @ChrissKonig @PharmacoJournal
Evolving resistance landscape in gram-negative pathogens: An update on β-lactam and β-lactam-inhibitor treatment combinations for carbapenem-resistant organisms
@Inox94 🙏 #idxposts
accpjournals.onlinelibrary.wiley.com/doi/pdf/10.100…
Català
SWB Guardians of Resistance me-retweet
Antibiotic resistance in Pseudomonas aeruginosa: mechanisms and emerging treatment
doi.org/10.1080/104084…
Română
SWB Guardians of Resistance me-retweet
🔥Everyone's favorite #shorterisbetter table is updated
Wow, 4 RCTs [non S.aureus] bactremia
7= 14
Spread the word #shorterisbetter #idxposts
Brad Spellberg@BradSpellberg
@Absteward has reported that BALANCE is now published, so the Table is now updated! GNB bacteremia is now listed as Bacteremia (non S. aureus). Neary 5,000 patients have now been randomized to 1 vs. 2 Constantine Units for non S. aureus bacteremia. bradspellberg.com/shorter-is-bet…
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SWB Guardians of Resistance me-retweet
No evidence of difference in mortality with amoxicillin versus co-amoxiclav for hospital treatment of community-acquired pneumonia - Journal of Infection journalofinfection.com/article/S0163-…
English
SWB Guardians of Resistance me-retweet
Lets talk about Antibiotic PK. This week's 🧵: Distribution!
This is where the drug goes after it's absorbed/injected. Where it goes = what target sites it can be used at.
Main drug factors: Hydrophilic vs Lipophilic, plasma protein binding, and peripheral tissue binding
1/9
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SWB Guardians of Resistance me-retweet
Is de-escalation from echinocandins to azoles a safe strategy in patients with candidemia?
🆕️🔥Systematic review & meta-analysis evaluating the clinical outcomes of antifungal early DES (<7d) in Candida infections in a relatively large sample size
ijidonline.com/article/S1201-…
English
SWB Guardians of Resistance me-retweet
How many nurse hours could your Trust release on introducing an effective #IVOS pathway?
The numbers are eye watering, take a look!👇🏻
#BSACWinterConference
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