criptoculto

71 posts

criptoculto

criptoculto

@criptoculto369

Bergabung Kasım 2025
83 Mengikuti9 Pengikut
Seth Howes
Seth Howes@SethSHowes·
I’ve wanted to do this for a decade. But I never did - I refuse to give any company my DNA. It is me. So this week I sequenced my genome entirely at home. Literally on my kitchen table. I never exposed my DNA sequence to the internet. Not at any point. I used a MinION to do the sequencing (it’s smaller + weighs less than an iPhone). I used open-source DNA models for the analysis (Evo2 and AlphaGenome) running locally on a DGX Spark and Mac Studio. I traced mechanisms behind my family’s multigenerational autoimmune conditions that no clinician has been able to understand. When I set out to do this I didn’t know if it would actually work. It does. Your genome is the most private data you will ever have. You probably shouldn’t let it leave your house.
Seth Howes tweet mediaSeth Howes tweet mediaSeth Howes tweet media
Patrick Collison@patrickc

I'm lucky enough to have a great doctor and access to excellent Bay Area medical care. I've taken lots of standard screening tests over the years and have tried lots of "health tech" devices and tools. With all this said, by far the most useful preventative medical advice that I've ever received has come from unleashing coding agents on my genome, having them investigate my specific mutations, and having them recommend specific follow-on tests and treatments. Population averages are population averages, but we ourselves are not averages. For example, it turns out that I probably have a 30x(!) higher-than-average predisposition to melanoma. Fortunately, there are both specific supplements that help counteract the particular mutations I have, and of course I can significantly dial up my screening frequency. So, this is very useful to know. I don't know exactly how much the analysis cost, but probably less than $100. Sequencing my genome cost a few hundred dollars. (One often sees papers and articles claiming that models aren't very good at medical reasoning. These analyses are usually based on employing several-year-old models, which is a kind of ludicrous malpractice. It is true that you still have to carefully monitor the agents' reasoning, and they do on occasion jump to conclusions or skip steps, requiring some nudging and re-steering. But, overall, they are almost literally infinitely better for this kind of work than what one can otherwise obtain today.) There are still lots of questions about how this will diffuse and get adopted, but it seems very clear that medical practice is about to improve enormously. Exciting times!

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criptoculto
criptoculto@criptoculto369·
@PulseChainStats @BoehnerPapah There's an error on the FAQ. YOU CAN change your stake before 00:00 UTC (ONLY if the stake status is PENDING) and you'll suffer no penalties, just pay gas fee
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PulseChainStats.com | PulseChain Stats & Portfolio
Did you know we now have a full $HEX staking frontend 👀 View, stake, and manage all your positions in one place. A clean, modern UI paired with an estimated stake bonus calculator and EES simulation makes everything easier to understand and more visually intuitive Supports both eHEX and pHEX Try it yourself → PulseChainStats.com/buy/stake
PulseChainStats.com | PulseChain Stats & Portfolio tweet media
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criptoculto
criptoculto@criptoculto369·
@AwakenWithJP S people talk about Jesus and not how his crypto thingy froze people'd money.
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JP Sears
JP Sears@AwakenWithJP·
Why do you think Trump did this? a. Thought it was a good idea, but was out of touch. b. Actively trying to lose the few supporters he has left. c. He’s demon possessed/Netanyahu made him do it (same thing). What do you think? 👇🏼
JP Sears tweet media
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criptoculto
criptoculto@criptoculto369·
@nicksortor Rob billions of dollars in crypto vs posts picture of Jesus. What are you going to pay attention to?
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Nick Sortor
Nick Sortor@nicksortor·
🚨 JUST IN: President Trump responds to backlash over an image he posted which seemed to depict him as Jesus "It's supposed to be me as a doctor making people better, and I do make people better. I make people a lot better!"
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Екаша
Екаша@eqasha_·
Иностранцы, как вам тот факт, что нас, русских, ещё в школе учат собирать разбирать автомат Калашникова и потом мы сдаем этот навык на оценку? Чтобы получить «отлично» нужно было совершить сборку и разборку за 30 секунд У вас было такое?
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criptoculto
criptoculto@criptoculto369·
@TruePat10906538 @MegaGeopolitics The bible is full of examples of Israel going wild and God saying: "No cryfagging if you go on your own". Babilon took over then Babilon takes over now. Lots of cryfagging ensues.
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Mega Geopolitics
Mega Geopolitics@MegaGeopolitics·
BREAKING: Spanish Prime Minister Pedro Sanchez arrives in China today just after Trump announcement that he will cut off all trade with Spain for refusing to support Israel
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criptoculto
criptoculto@criptoculto369·
@otokyo__ She has a beautiful face in a fat body. Lucky her. She can stop eating carbs.
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Tokyo
Tokyo@otokyo__·
Can you believe a lot of men think that this is fat? Would you call her fat or curvy? Be honest.
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criptoculto
criptoculto@criptoculto369·
@otokyo__ Fat. Well, let me rephrase it. Nah, she's fat.
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Genius Tech
Genius Tech@Geniustechw·
WTF happened to George Clooney?
Genius Tech tweet mediaGenius Tech tweet media
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Honey 🛼
Honey 🛼@honeymoon250·
Any advice to her???
Honey 🛼 tweet media
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Marlayna
Marlayna@Marlayna29·
🤔
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criptoculto
criptoculto@criptoculto369·
@Matt_Pinner Same thing I'm already eating. Thanks for sponsoring my life
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criptoculto
criptoculto@criptoculto369·
@otokyo__ Close your eyes, think about Pamela Anderson at her best.
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Tokyo
Tokyo@otokyo__·
What advice would you give this donkey? 😅
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criptoculto
criptoculto@criptoculto369·
@Matt_Pinner One fucks your sister, one fucks local shops and the other fucks with your privacy
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Honey 🛼
Honey 🛼@honeymoon250·
Can you identify what wrong with this family?
Honey 🛼 tweet media
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Liberta Cherguia 🇪🇺
Liberta Cherguia 🇪🇺@MbarkCherguia·
Is it appropriate for 56-year-old Jennifer Lopez to dress like this at her concert?
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LadyValor
LadyValor@lady_valor_07·
Based on the entirety of this photograph, what is your best estimation of the year it was taken?
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criptoculto
criptoculto@criptoculto369·
@_vmlops Big guys every time you connect...
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Vaishnavi
Vaishnavi@_vmlops·
GOOGLE JUST MADE IT DEAD SIMPLE TO CONNECT AI AGENTS TO ANY DATABASE postgres, mysql, mongodb, bigquery, redis, elasticsearch, spanner, snowflake. 20+ databases supported mcp toolbox is an open source...mcp server that gives your ai agents direct access to your enterprise databases in plain english no custom connectors, no boilerplate, built-in connection pooling, auth, and opentelemetry out of the box works with langchain, llamaindex, genkit, and any mcp-compatible client less than 10 lines of code to plug it into your agent github.com/googleapis/mcp… this is google making database access the easy part of building ai agents
Vaishnavi tweet media
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Johnny Chaos
Johnny Chaos@ccfxstudios·
Collectors mindset.
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