Debbie Montjean

@GLiperis Treatment personalization.. one size doesn´t fit all🤷🏽‍♀️#ESHREjc

4.5 In Summary the authors conclude that double biopsy and double vitrification might not be the best option for all patients. It's crucial to balance genetic testing needs with the potential risks to clinical outcomes.

📢 #Tweetorial alert! Are you excited for the first #ESHREjc of the year? @ESHRE ‼️ DOUBLE TROUBLE ‼️ We are discussing the recent systematic review&meta-analysis by Bickendorf et al., 🇦🇺 on double biopsy & ❄️vitrification doi.org/10.1093/humrep… 🧵 Here's what they found 👇

@GLiperis Poor training! #ESHREjc

Q2 of the #ESHREjc is underway! What are the sources of amplification failure?

@AndrewIVFSAS @juanjo_fraire @GLiperis @OmarRawi89 @SCobanMune @zoyaalii_ @kashish__ @BasselWattar @alteri_ale If technical aspects cannot be standardized then they must be controlled for. This is why statistical analyses must be done appropriately by trained persons. #ESHREJC

@debsmtj @juanjo_fraire @GLiperis @OmarRawi89 @SCobanMune @zoyaalii_ @kashish__ @BasselWattar @alteri_ale For technique, how do we decide what the best one is to standardise against? This is particularly difficult in labs where staff turnover is higher and/or you have a lot embryologists coming in with a higher skillset/were trained in different labs

Q1. What are the limitations of the 📝 due to the analysis of retrospective datasets 📈 and the sources of heterogeneity? How can we better plan 🤔and assess 🕵️‍♀️ future studies to avoid these limitations? 🧐 #ESHREjc

@alteri_ale @AttilioDGM7 @juanjo_fraire @GLiperis @OmarRawi89 @SCobanMune @zoyaalii_ @kashish__ @BasselWattar @AndrewIVFSAS And poor quality embryos won´t survive the biopsy+freezing or won´t result in a pregnancy. Therefore embryo grading and selection remains crucial. #eshrejc

@AttilioDGM7 @debsmtj @juanjo_fraire @GLiperis @OmarRawi89 @SCobanMune @zoyaalii_ @kashish__ @BasselWattar @AndrewIVFSAS Poor quality of the TE cells can contribute to the risk of an inconclusive biopsy #ESHREjc

📣 Are you excited as we are for the 1st #ESHREjc of the year? Is it safe to perform double biopsy&double vitrification in our labs? Join the discussion this coming Friday-Saturday 17:00 CET start-stop. 👀 Amazing illustration of the paper from the talented @diana_tain90 👇🏻

The Global Fertility Care Community of Practice invites you to this upcoming webinar   The Intersection of Intimate Partner Violence & Infertility: A Global Perspective.  Wed Jun 26th, 2024 3:00-4:00pm CET Please use the link //bitly.cx/UBnior QR Code below to register.

CoP is a group of people who share a common interest and experience the same issues. A Global Fertility Care Community of Practice was created and is hosted by the IBP Network and includes healthcare professionals and researchers: globalfertilitycare@groups.ibpnetwork.org

🔹 New article online 🔹 Results from a preliminary study highlights the potential of virtual reality as a non-pharmacological solution to alleviate stress and elevate satisfaction during ultrasound-guided oocyte retrieval. Find the full article here 👇 focusonreproduction.eu/article/News-i…

@alteri_ale @alphascientists @LParmegiani Congrats 🤩🤩🤩🥳🥳

Extremely happy to receive the award for the best free communication. Thanks to @alphascientists and the Executive Committee #AlphaConference2022 🙏🙏🙏 Thanks to my friend and Ph @LParmegiani 🤩

@ESHRE @marcos_meseguer Thanks for the invitation! I enjoyed being à part if the discussion 💙

Many thanks to the experts @marcos_meseguer @debsmtj 🙌 and author Dr Amy Barrie for their valuable input 👍 #ESHREjc

Many thanks to all participants 🙌 and to @SCobanMune and her team for leading this great edition of the #ESHREjc

@juanjo_fraire @Dr_Georges_Raad @SCobanMune @marcos_meseguer @yannisfontouris @ESHRE @CARE_Fertility @alicamp76622539 @simonfishel_ivf

@Dr_Georges_Raad @SCobanMune @marcos_meseguer @debsmtj @yannisfontouris @ESHRE @CARE_Fertility @alicamp76622539 @simonfishel_ivf Thanks for participating actively! 💪🏼💪🏼#ESHREjc

🧙‍♀️Our January #ESHREjc is about to finish‼️ 😪 🧙‍♀️Thanks to everyone joined, especially our 🌟experts: @marcos_meseguer @debsmtj @yannisfontouris @ESHRE 🧙‍♀️Huge thanks to the authors of the paper @CARE_Fertility @alicamp76622539 @simonfishel_ivf

@eguellp @SCobanMune @kashish__ @marcos_meseguer @yannisfontouris @juanjo_fraire @KohlheppFlorian @OmarRawi89 @ESHRE @cilerozenci @SIGAndrology The authors said that their TL system took 1 photo every 20minutes on 7focal plans. What if the setting was different? Photos taken more frequently? Would that make a significant difference in term of PNs timing observation? #ESHREjc #ESHRE

@SCobanMune @kashish__ @marcos_meseguer @debsmtj @yannisfontouris @juanjo_fraire @KohlheppFlorian @OmarRawi89 @ESHRE @cilerozenci @SIGAndrology I think it is truly important to state if insemination technique was IVF or ICSI as t0 can varies up to 3 hours!

#ESHREjc Q2.What factors affect the timing of PN appearence/fading⁉️🧫🧬🌡️ In this study over 200ICSI and 100IVF derived embryos that produced LB would have been deselected if PN check would take place at recommended timing without TLI🔬🤯 Should TLI be considered as standard⁉️

@KohlheppFlorian @alicamp76622539 @kashish__ Embryo morphokinetics vary with culture conditions( culture medium, culture system,O2 tension, %CO2, humidity) and patients related factors. All these parameters need to be taken into account and ajustée on before generalizing fert check at 16.5hpi

@alicamp76622539 @kashish__ Do you think the timings can be transferred 1:1 into a different lab setting or is a fine-tuning needed to account for lab-specific differences? #ESHREjc

@OmarRawi89 @juanjo_fraire @SCobanMune @KohlheppFlorian @eugin_en @CIRH_Barcelona @yannisfontouris But this was nearly 5years ago... which sounds like prehistory in our field #ESHREjc

@OmarRawi89 @juanjo_fraire @SCobanMune @KohlheppFlorian @eugin_en @CIRH_Barcelona @yannisfontouris I know🤷🏽‍♀️

Q1. It’s a poll time 😎📊 #ESHREjc In your routine lab protocols, when do you check your fertilisation post insemination? Please also do discuss your opinions under the poll.

@juanjo_fraire @SCobanMune @OmarRawi89 @KohlheppFlorian @eugin_en @CIRH_Barcelona @yannisfontouris FYI, and only 17% in USA in 2017 pubmed.ncbi.nlm.nih.gov/28600620/

@juanjo_fraire @SCobanMune @OmarRawi89 @KohlheppFlorian @eugin_en @CIRH_Barcelona @yannisfontouris The last survey conducted in France concluded that 39% of IVF lab have TLT... which doesn't mean that they use it...😒pubmed.ncbi.nlm.nih.gov/30187427/

@SCobanMune @OmarRawi89 I am equipped with TLT. PNs are never missed🤑💪🏽😁

@OmarRawi89 @debsmtj How do you do in your clinic? #eshrejc

@SCobanMune @kashish__ @marcos_meseguer @yannisfontouris @juanjo_fraire @KohlheppFlorian @OmarRawi89 @ESHRE @eguellp Sperm factors (quality, motility, morphology, surgical or native) may indeed affect fertilization events and subquent embryo morphokinetics #ESHREjc #ESHRE here is a recent reporthttps://pubmed.ncbi.nlm.nih.gov/32119189/ 🧐

@kashish__ It is not reported in the paper whether differences in Sperm parameters where adjusted for in IVF/ICSI cycles analyzed. Could sperm quality have impacted the dynamics? @marcos_meseguer @debsmtj @yannisfontouris @juanjo_fraire @KohlheppFlorian @OmarRawi89 @ESHRE #ESHREjc @eguellp