Valentin Dunsing-Eichenauer

New preprint: We have developed an integrated pipeline to i) image gastruloids in toto with dual-view 2-photon🔬, ii) quantitatify cell and tissue-scale patterns of gene expression and morphometric features, iii) interact with the data in @napari_imaging. biorxiv.org/content/10.110…

Introducing #NovaFLIM: our new #fluorescence lifetime imaging analysis software. It is designed for an efficient and multi-faceted analysis of #FLIM, FLIM-FRET, and #anisotropy. ➡ Learn more: picoquant.com/products/categ…

📢Our preprint list is now up on FocalPlane. This list is focussed on new research in bioimage analysis. Drop us a message if there is a preprint that we've missed! focalplane.biologists.com/2024/09/06/mic…

#Gastruloids have many uses as #models for: early mammalian development, #SelfOrganization, mapping signalling/gene expression, morphogenesis. Here @Equipe_lenne use’m to develop gral tools to image gene/protein expression at diff scales biorxiv.org/content/10.110… #InNumbersWeTrust

📡🧵 Excited to release our preprint: Ultrack: Pushing the Limits of Cell Tracking Across Biological Scales doi.org/10.1101/2024.0… A tour-de-force by @jobragantini, #Ultrack is a versatile, highly accurate, and fast ILP-based cell tracking software for 2D, 3D, and multicolor datasets. It has convenient @napari_imaging and @FijiSc plugin interfaces and built-in HPC cluster support. github.com/royerlab/ultra… #cell_tracking #microscopy #devbio @czbiohub

A first step towards a basis for research on #StemCell based #EmbryoModels rdcu.be/dSHtz @NatureCellBio We hope that this will be useful in this new field where quality control and appropriate criteria are needed

Happy that I could contribute 🙂 Flipper-TR also works well with 2-photon excitation 👇. It will be interesting too see in different systems what the probe can tell, and on which time scales. In this context, fast FLIM will be useful. Our attempt here: biorxiv.org/content/10.110…

All what you wanted to know about using flipper probes @spirochrome @matile_group for cell biology and didn’t dare asking is in: rdcu.be/dSmET Thanks to all co-authors and colleagues, thanks to @CRoffay & @vincent81196538 for their great work!

@Laura_Breimann @napari_imaging Thanks Laura! 😀 I hope you are doing well!!

@DunsingValentin @napari_imaging This looks great, Valentin! Congrats 😃

New preprint: We have developed an integrated pipeline to i) image gastruloids in toto with dual-view 2-photon🔬, ii) quantitatify cell and tissue-scale patterns of gene expression and morphometric features, iii) interact with the data in @napari_imaging. biorxiv.org/content/10.110…

🚨📢Our paper on imaging, segmenting, visualising and measuring patterns in gastruloids across spatial scales w/ @napari_imaging is out‼️ An project led by @_AliceGros, @JVanaret, @DunsingValentin et al.🤓 A collab. between @Equipe_lenne, @PhilippeRoudot's and our lab. ⬇️Link⬇️

*quantify 😉

This was a great team effort together with co-first author PhD students @_AliceGros and @JVanaret, jointly supervised by Sham Tlili, @Equipe_lenne, @GuignardLab and @PhilippeRoudot @IBDMmarseille @centuri_ls. All code is available here: github.com/GuignardLab/ta…. Feedback welcome!

Interested in diffusion and oligomerization? Our brightness-transit statistics pipeline based on sFCS acquisitions just came out in @NatureComms 🥳 Start correlating! Great collab with @pfcespedes @KaredlaNarain @FritzscheLab @MichaelLDustin nature.com/articles/s4146…

Great to be back in Basel for #BaCell3D. I will present a poster (#216) tomorrow on in toto imaging of organoids, which we use to investigate patterning mechanisms in gastruloids. Looking forward to discuss.

🧐 unexpected blue-shifted photons !!! 🔬🟥➡️🟦😱😱😱 Great work @AgEggeling @carravilla_p @_Dasgupta_A @uiztok et al

PhD position in Mechanobiology in Marseille! Are you excited to study how mechanical forces impact the transcription of muscle nuclei as well as muscle metabolism? Join us at our fantastic campus in Marseille. thenode.biologists.com/jobs/phd-posit… @Fly_EDS @IBDMmarseille @CNRSbiologie #muscle

I’m so happy to share another story from my PhD with @ErcanLab and @preibischs, where we studied the gene regulation in the dosage compensation system of C. elegans using smFISH! Here are a few highlights…🧵 biorxiv.org/content/10.110…

🔬🌟Join us for the 3rd @centuri_ls Hackathon for Quantitative Biology in Marseille!💥Both wet and dry lab people are welcome! Dive into amazing projects and experience this year stunning location!🌍 Registration now open!🚀💻#HackBio #QuantBio ⬇️Don't miss out, sign up now!⬇️

@KStapornwongkul @PRecouvreux Thanks! And great, looking forward! I already have a comment to the comment to discuss 😄

@DunsingValentin @PRecouvreux Congrats Valentin! Will read it in more detail so we can discuss it in Barcelona 😉.

Very happy that I could contribute to this work led by @PRecouvreux. It has always fascinated me how cells coordinate using morphogens. When I started to get interested in biology, C.elegans was the first organism that we imaged at a🔬. Here, both came together with in vivo FCS.

The paper is available here: authors.elsevier.com/c/1ivFB3QW8S6E…