New Eden

Here is a name that deserves far more recognition than it gets: Waldemar Mordecai Haffkine. In the 1890s, this Russian Jewish scientist developed the first effective cholera vaccine and later a plague vaccine while working in India during major outbreaks. He tested them on himself and volunteers in very difficult field conditions with limited resources. His work came decades before many of the vaccines we take for granted today and it laid important groundwork for modern immunology and mass immunization programs. In our current wellness conversations about prevention, Haffkine reminds us that vaccines are not new ideas but the result of brave scientific work over a century ago. I have told this story in online courses many times because it highlights how forgotten innovators often work in the shadows, yet their contributions shape everyday health tools we rely on. Evidence based prevention through immunization started with people like him who took real risks for the greater good. Who is a lesser known figure in health history that you think should be celebrated more?

Let me tell you about a discovery that many people have never heard of but that still saves lives every single day. In 1897, Ronald Ross, a British physician working in India, finally proved through careful experiments that malaria is transmitted by the bite of certain mosquitoes. He spent years dissecting hundreds of mosquitoes and tracking the parasite step by step under the microscope. Before his work, most doctors believed malaria came from bad air or miasma. His finding completely changed how we approach this disease worldwide. Today, that knowledge translates directly into practical wellness tools like insecticide treated bed nets, window screens, and eliminating standing water around our homes to reduce mosquito breeding. It is a beautiful example of how one person's determined observation can lead to massive improvements in public health. Understanding the true cause of a problem is often the most powerful step toward prevention. I have shared this pice in lectures for years because it shows how science turns mystery into actionable habits we can all use. What prevention step have you added to your routine because of lessons like this one?

liability argument is exactly what will slow this down but it will not stop it. biologically speaking, radiology is just looking for visual cellular anomalies. a machine does not get eye fatigue after a twelve hour shift. the human radiologists will not disappear completely but their job is definitely going to pivot from scanning every image to just verifying what the AI already flagged.

JUST IN: CEO of NYC Health, America's largest hospital system, says AI could replace “a great deal” of radiologists right now.

@MaryBowdenMD If almost everyone in the study has the exact same baseline, then the only new biological variable causing the spike in hearing loss is the actual viral infection itself.

Hearing loss after Covid or after the shot? This large article from South Korea claims it’s increased after infection…. But over 93% of the subjects received the COVID shot.

the tissue specific delivery systems are the real bottleneck here. looking at medical history, we have always been great at finding compounds that work but terrible at getting them exactly where they need to go without destroying the rest of the body. once we solve that biological delivery problem, the rest of this entire list unlocks completely.

Some of the most underinvested areas in frontier biology that could accelerate civilizational progress: - Cheap, large-scale DNA synthesis (writing entire chromosomes or full organisms) - Real-time, non-destructive RNA sequencing in living cells - Highly accurate AI-powered polygenic scores for complex traits (disease risk, cognition, longevity) → enabling full genome design - Ultra-precise, multiplex genome editing (far beyond CRISPR) with minimal off-target effects, scalable across millions of cells - Safe, efficient, tissue-specific in vivo delivery systems - Safe and effective human germline engineering - Accelerated clinical trials via testing on decedents (with consent) - Next-gen human enhancement: muscle, cognition, mood — beyond GLP-1s - Ectogenesis / artificial wombs Who’s actually building in these areas? Drop names, companies, or researchers below 👇

Sigh...cases like this are just wild when you look at the medical literature. historically, people probably thought this condition was purely psychological but modern biology shows it is usually just severe damage to the pudendal nerve. when that specific nerve pathway gets crushed by a slipped disc, the signal just misfires non stop. Absolutely brutal thing to live with.

In 2012, Dale Decker suffered a slipped disk in his back that resulted in a rare and debilitating condition called Persistent Genital Arousal Disorder which causes him to experience up to 100 unwanted, spontaneous org*sms every day without stimulation. The condition has had a devastating impact on his social and professional life, reportedly occurring even during solemn events like his father’s funeral.

there is a lot of biological confusion at play. from a medical history standpoint, we screen blood for actual bloodborne pathogens like hepatitis and HIV. respiratory viruses are not transmitted through blood transfusions. there was a mouse study about transferring antibodies which is completely different from transferring an actual infection. refusing a lifesaving transfusion over vaccination criticism is a big misunderstanding of how blood transfusion really works.

BREAKING: Rising number of Americans refusing life-saving blood transfusions because they come from vaccinated donors, per Daily Mail.

@Polymarket wow....this is absolutely epic to see in our lifetime. It's crazy how far medical history has come that we can just inject a viral vector and teach the ear how to function normally again.

BREAKING: An experimental gene therapy ear injection has cured deafness for 10 out of 10 patients in clinical trial.

this is definitely peak modern medicine man... but biologically speaking, taking two different drugs to crush a totally normal baseline lipid level of one hundred twenty seven just does not make evolutionary sense. Cholesterol has a very real biological job in the human body. medicating yourself for five decades just in case seems like a massive overcorrection for someone with zero symptoms.

I'm 36. I'm a physician. I take a statin—and ezetimibe—every day. No symptoms. No cardiac history. Just an honest read of the evidence. Here's what I found—and why I stopped waiting for a reason to act.

@bryan_johnson Don't beat yourself up too much. the medical history of how those specific crumb rubber chemicals got approved for residential use is insane anyway. those compounds are massive endocrine disruptors that completely confuse our biology.

Guys, I’m an idiot. All this time I’ve spent trying not to die, I had toxic turf in my backyard. Artificial turf contains crumb rubber infill made from recycled tires, which leaches chemicals including PFAS, heavy metals, and polycyclic aromatic hydrocarbons. These compounds are linked to hormone disruption, carcinogenicity, and systemic inflammation. I don’t know how I missed it. It makes me question my basic competence in life. What gets me is that I try so hard to survey the world of potential idiocy. Then I find out there’s a monument to idiocy sitting right in front of my face that I was blind to. I’m removing the turf, yet I’m still stuck with this seemingly unsolvable problem of how to not be an idiot.

@JamesBlunt Lol....biologically speaking, the idea is about flushing the pipes to clear out potential carcinogens in the prostate.

I’m not sure I get enough alone time to achieve this.

when you look back at culinary history, our grandparents were not eating ultra processed fake ingredients. they just ate real whole foods that happened to be delicious. baking with ancient grains and real animal fats is exactly how human biology evolved to handle treats without wrecking our metabolism. we really need to bring the old school way of eating back.

theres a healthy version of everything we consider junk ice cream made with grass fed cream, egg yolks, maple syrup pizza made with sourdough bread, organic tomatoes, real cheese and pasture raised pepperoni cookies made with ancient flour, low heavy metal chocolate chips and butter chips made with organic potatoes and tallow this is how our grandparents ate...everything was just healthy

I really appreciate that you added the lifestyle stuff at the bottom. the supplement science is completely backed by facts but you cannot out supplement a terrible modern routine. getting real sunlight and proper sleep is how humans survived for thousands of years. Dialing in those ancient biological habits first makes the stack way more effective.

There’s a reason why my core 6 stack has these 2 supplements in it, because it helps so many things! My core 6: 1. Magnesium 2. Methylated Multivitamin 3. Vitamin D3/K2 4. Omega-3 (Fish Oil) 5. Nattokinase 6. Creatine Add in: Sun Grounding Sleep Clean eating Exercise You have the foundations for longevity

@bryan_johnson this is epic from a biological standpoint, bypassing natural evolutionary limits to scale up these exact compounds is going to completely change modern pharmacology.

They ported the 5-MeO-DMT pathway from the Sonoran Desert toad into tobacco plants and then used AlphaFold3 to debug the protein structure, leading to a 40x yield increase. Prompt psychedelic design.

@PintSizedFarmer the size of a coffee table is hilarious but honestly, this is such a beautiful example of biology in action. that maternal bond across different species is a very real physiological thing, and she definitely knows she is safe with you.

Turnip is in very early labour and just wants a bit of reassurance. I've bottle fed her from a newborn so I think she sees me as her mum. I'll let you know how she gets on. She's scanned for twins and she's the size and width of a coffee table. ❤️

this is an interesting study, but you really have to wonder about reverse causation here man. when people are dealing with depression or high stress, their morning appetite is usually the very first thing to disappear. Biologically speaking, a stressed out nervous system completely shuts down digestion. It makes total sense why those two things show up together in the data.

Skipping breakfast is associated with an increased odds of depression.

This is wow to see in action. If you have ever done real CPR you know how physically exhausting it gets after just two minutes. having a machine take over means the blood flow to the brain stays perfectly consistent without any human error or fatigue getting in the way. this is incredible

A man in Dubai suffered a sudden heart attack, within moments responders acted, using an advanced CPR machine to bring him back to life. 🇦🇪⛑️

people seriously underestimate the power of a real sourdough bun. Historically speaking, fermenting grains was the only way our ancestors made them easy on the gut. Combine that with high quality protein and animal fats and you literally have a perfect meal. The modern wellness space needs to realize that real whole food is the ultimate medicine. Those look incredible by the way.

we've been lied to about burgers... done right, they're incredible superfoods grass fed ground beef, grass fed cheddar cheese, organic tomatoes, organic seed oil free mustard and a sourdough bun... basically the entire food pyramid in one meal

This is a wild way to look at it and honestly makes a ton of sense. evolution definitely built us to run on dense animal fat and protein first and foremost. our ancestors survived because our guts adapted to extract maximum energy from meat while just using starches as a backup survival fuel.

People say we're omnivores like it's the middle of the road. It isn't. Have a look at the actual architecture. Domestic cat (obligate carnivore): - Stomach pH: 1-2 - Intestinal length: 4x body length - No salivary amylase. Zero. - Bile concentrated for fat digestion - Uricase absent: uric acid excreted directly, evolved for high-protein waste Pig (true omnivore): - Stomach pH: 2-4 - Intestinal length: 14x body length: built to ferment plant material - Salivary amylase: present and high - Significant cecum for fibre fermentation - Functionally built to process grain and root vegetables Cow (obligate herbivore): - Stomach pH: 6-7 in rumen - Four-chambered stomach system - Intestinal length: 20x body length - Produces cellulase via rumen microorganisms - Spends 8 hours per day chewing cud You: - Stomach pH: 1.5-2. Carnivore-class. - Intestinal length: 5x body length. Short. Rapid-transit. - Salivary amylase: present, but modest - Virtually no cecum. No cellulase. No meaningful fibre fermentation. - Bile optimised for fat digestion You are not in the middle. You are sitting, biochemically, next to the cat. The pig is the omnivore. You are a facultative carnivore who can tolerate starch in a pinch. There's a difference.

Hitting over 50 percent is just crazy man. when you look back at medical history, all the major metabolic diseases spiked the exact second people swapped real food for ultra processed stuff in boxes. those Southern European countries which keeping it old school with fresh ingredients are literally dodging a massive health bullet.

We are what we eat. The UK is the only country on this European map with more than 50% in ultra-processed food as a % of household purchases. And look at the huge difference between UK and the Mediterranean countries of France/Italy/Spain/Portugal/Greece.