Stephen Kent

Strong link between early viral load reduction by anti-COVID treatments and clinical efficacy. Helps rapidly progress better treatments. Bravo, great work by Khoury, Davenport and team. @IAP_Sydney @TheDohertyInst @KirbyInstitute @viralvaxlab medrxiv.org/content/10.110…

@DrRenly This wasted effort is against every principle of scientific progress and scientific workforce development #MRFF. FIX IT. Fund the next best 150 grants WITHOUT reapplication. @sciencegovau @edhusicMP @MarkPButler

Am I the only one who feels disturbed looking at these stats? 307 teams of #ECRs spent countless hours putting in applications with 9 awarded (2.9% success rate). #mrff #emcr #AcademicTwitter #postdoc health.gov.au/sites/default/…

Great work team! Yes, keep getting your vaccines people. Although the difference between WT and variant boosters is pretty subtle in some healthy subjects, the variant booster will help some vulnerable groups stay out of hospital.

This is super important. Severe COVID is THE major issue today. Neutralising antibodies protect against severe COVID.

Research Highlight rdcu.be/c8pFw on a paper by Juno and colleagues that examines T cells frequency and phenotype after Delta and Omicron breakthrough infection in previously vaccinated individuals.

Crazy strong link between Nab and protection from severe COVID, p <2.2e-16. Superb work by @DebCro, the Davenport group and collaborators. @KirbyInstitute @TheDohertyInst medrxiv.org/content/10.110…

Our latest preprint shows that neutralising antibodies predict protection from severe COVID-19. Great collaborating with @ProfStephenKent @m_steain on this important work from the @KirbyInstitute medrxiv.org/content/10.110…

More brilliant work from David Khoury and team. Elegantly reconciles protective immunity by Nab from multiple angles. Correlates of protection, thresholds of protection, and immunobridging in SARS-CoV-2 infection medrxiv.org/content/10.110…

@vanGilsLab @hecklab @amsterdamumc Nice Marit and team. MS is a good way to follow clones over time too. nature.com/articles/s4146… Looking forward to your link up with Mabs.

Great work by @hecklab on detailed polyclonal SARS-CoV2 antibody responses after VOC infection. Honored to be able to collaborate with this fantastic team! #Antibodies #teamwork @amsterdamumc

@Hyonxhi @SciImmunology Fantastic study, superbly led by HX and Adam and amazingly well supported by the whole team. Go BRMs and their Abs! Likely where the action is at controlling Flu, COVID-19 and other acute respiratory pathogens. You should be lodging a few as we speak HX!

Sup' peeps. Two events happened this week: 1) Getting COVID (mild so far 🙏) 2) Our study on tissue-resident memory B cells (BRMs) out in @SciImmunology science.org/doi/10.1126/sc… Plenty of literature around tissue-resident T cells. What about B cells? I’ll unpack this study here:

@ProfPCDoherty Or preferentially boost antibodies to conserved unhelpful epitopes in original strain? (Imprinting/Original Ag sin) cell.com/trends/immunol…

@c_phetsouphanh @NatImmunol @DavidDarley_ @Dan_B_Wilson @GregDore2 @KirbyInstitute @TheDohertyInst Great work Chan and team. Super insightful into long covid. Honoured to have been involved. #viralvaxlab

On paper on immune dysfunction during #longCOVID is now publish @NatImmunol. @DavidDarley_ @Dan_B_Wilson @GregDore2 @KirbyInstitute @KentLaboratory @TheDohertyInst nature.com/articles/s4159…

@viralvaxlab @MariosKoutsakos @WenShiLee Nice thread! Couldn’t have been done without clever immunologists, cool assays, and super dedicated participants who were so altruistic. Another big inroad into covid immunity with the Davenport group.

Happy to share our new preprint led by @MariosKoutsakos and @WenShiLee medrxiv.org/content/10.110… We characterise the recall of SARS-CoV-2 humoral and cellular immune responses after vaccination of seropositive individuals or breakthrough infection of vaccinated individuals. 1/14

Nervous about the ability of new vaccines to combat COVID variants. Our immune systems can recognise the old strains better than the new ones, called "immune imprinting". Discussion piece out in Trends in Immunology. doi.org/10.1016/j.it.2… @WheatleyAtotheK @scientist_JJ @Hyonxhi

Super proud of Jen, Hyon-Xhi and Amy on the announcement of their NHMRC Investigator awards. Richly deserved in a crazy crazy tough system. Allows them to dream even bigger. Will be exciting to watch over the next 5 years. Congrats @scientist_JJ @Hyonxhi @AmyWChung

Congratulations, especially to Adam and the team @KentLaboratory

The Kent lab is hiring! We're looking for a project manager to help co-ordinate our recently funded next-generation COVID-19 clinical vaccine development project 💉 doherty.edu.au/news-events/ne… More information and application below 👇 jobs.unimelb.edu.au/caw/en/job/906…