Timothée Bruel

SARS-CoV-2 continue to surprise us with evolutionary jumps. In this pre-print, we describe the Identification and genomic characterisation of BA.3.2: a highly divergent BA.3-related SARS-CoV-2 lineage from southern Africa. A thread 🧵 medrxiv.org/content/10.648…

🚀 New preprint! The Human Cytokine Dictionary - 9.7M cells, 12 donors, 90 cytokines - our largest human single-cell perturbation atlas yet. Users can map cytokine activity in their own data. Huge thanks to Lukas, Sören, Larsen, Parse Bio & Seelig lab! 🔗 biorxiv.org/content/10.648…

Public trust in science has declined since COVID — virologists need to unite around safety standards nature.com/articles/d4158…

With 30 new BA.3.2 sequences from the Netherlands and Denmark uploaded today, this is beginning to have a look of inevitability about it. Still waiting for a recombinant that restores ORF7a, ORF7b, and ORF8 (all entirely deleted in BA.3.2).

We're learning how to control our immune system and cure some patients with autoimmune diseases, like lupus and multiple sclerosis. After CAR T (vs protein on B cell surface, CD19 or CD20) the new B cells are rebooted, no longer self attack

The Journal of Virology is proud to announce the selected candidates of the inaugural New Voices in Virology minireview collection. Congratulations to these early-career virologists who were chosen from over 275 applicants. See journals.asm.org/journal/jvi/jv…. #virology @JVirology

Check out our new paper on molecular characterization of RSV infections in elderly patients during the 2023/2024 season in the era of nirsevimab introduction, just published in JID pubmed.ncbi.nlm.nih.gov/39895281/

🚨 Preprint alter - bis 🚨 I am thrilled to share our last preprint where we identify and characterize a new coronavirus receptor! 🦠 This work was done in collaboration with the team of Félix Rey @virusfusion007 at the Institut Pasteur. A 🧶 below... biorxiv.org/content/10.110…

🚨 New preprint alert 🚨 We searched for the presence of coronaviruses in >200 bat individuals across Spain 🦠🦇🇪🇸. We recovered 6 complete coronavirus genomes, including 3 novel species. One of them could use bat and human ACE2 for entry. biorxiv.org/content/10.110…

🎉 La Société Française de Virologie vous souhaite une excellente année 2025 !  ✨ Que cette nouvelle année soit riche en succès pour toute la communauté scientifique. 🦠 Rendez-vous aux #JFV2025 pour écrire ensemble une nouvelle page en virologie ! 🔬 #BonneAnnée2025

Antiviral activity of #Tecovirimat against #Mpox virus clades 1a, 1b, 2a and 2b in cell culture. Collaborative work with @Guardado_Calvo @SimonLoriereLab and JC Manuguera @institutpasteur biorxiv.org/content/10.110…

🎉 Aujourd'hui, nous célébrons l'anniversaire de la naissance de Louis Pasteur. Son héritage scientifique continue d'inspirer nos recherches pour relever les défis de santé publique d'aujourd'hui et de demain. #LouisPasteur

A must read ! We need a better model to predict antibody effector functions. journals.asm.org/doi/full/10.11…

1/ We are excited to share our new paper from @alqurefa published today in @JExpMed about humans with autosomal dominant IFNAR1 deficiency (doi.org/10.1084/jem.20…).

Get ready! Negative Strand RNA Virus meeting #NSV2025 registration will open soon! Co-organized with @wendybarclay11, @vsv512 and Paul Duprex. It will be in vibrant Montpellier, south of France, in June 2025! Please RT

"AI will not replace people anytime soon, but people who use AI might replace those who don’t." nature.com/articles/d4158…

🎉 Bravo à @michaelwhite_36, chercheur à l’Institut Pasteur, lauréat de l'ERC Consolidator Grants ! Son projet ULTIMASero explore les maladies infectieuses via des tests multiplex, études épidémiologiques et modélisation statistique.

The combination of nivolumab and ipilimumab in patients with metastatic colorectal cancer led to 24-month progression-free survival of 72%, as compared with 14% with chemotherapy. Read the full CheckMate 8HW trial results: nej.md/4eGp1tj

@CIML_Immunology 👏👏👏

For the latest CIML news, please follow us in 🦋 Bluesky: bsky.app/profile/ciml.b…. See you there!

A new @ScienceAdvances study of more than 482,000 Wikipedia readers identifies the knowledge networks associated with the three main styles of curiosity. Learn more: bit.ly/3YHzaQA