Carlos Fernandez, PharmD

bit.ly/4l4k1mv Advancing clinical management of left ventricular thrombosis: prevention, detection and treatment modalities in the modern era

Approximately 80% of all strokes are ischaemic. The underlying pathology is often multifactorial, involving interrelated arterial and cardiac conditions. Identifying the specific cause of stroke is critical for short-term and long-term care. Learn more: ow.ly/C44P50WluMQ

☝️No estimate of the apoB lipoprotein-related risk of CVD is complete without measurement of both apoB and Lp(a) ApoB is the true core marker of atherogenic particle burden, and Lp(a) is an independent, non-negotiable player in cardiovascular risk. ✅ ApoB reflects the number of atherogenic particles, not just the cholesterol they carry. ✅ Lp(a) adds risk beyond ApoB—even in normolipidemic patients. ✅ The combination of both offers superior prediction of events and treatment guidance. 👉 It's time to stop counting cholesterol and start counting particles. If your risk assessment doesn’t include ApoB and Lp(a), you’re not seeing the full picture. Let’s raise the bar in preventive cardiology. doi.org/10.1093/eurhea… @society_eas @fhpatienteurope @escardio @ehj_ed

ICYMI: The ACC recently launched a comprehensive resource package, "HF in a Box," designed to support clinicians in the management of #HeartFailure. All resources address HF GDMT & are available free of charge in both English & Spanish. Find out more: bit.ly/3SotOXR

This is a very good review of type 2 diabetes jamanetwork.com/journals/jama/…

How low can you go…😉

@AKECassels @4_doctors It depends on her risk & other clinical factors. Age alone is not enough to determine yes/no. 😉

SHOULD A 60 YEAR OLD WOMAN TAKE A STATIN? , by @4_doctors open.substack.com/pub/fifthdocto…

@HeartOTXHeartMD Died too young…

This is a great obituary. Didn’t know that he was Jason Sudiekis’ uncle either! Comedic family. #RIPNorm

Break down key updates from the @nkf’s 2025 Spring Clinical Meetings—now streaming on @medliveofficial. This free, #CME-credited program offers practical insights into diagnosing and managing two rare forms of #KidneyDisease: C3 glomerulopathy (#C3G) and primary immune complex membranoproliferative glomerulonephritis (#ICMPGN): bit.ly/42RjfB9 #Nephrology #C3Glomerulopathy #Glomerulopathy #Glomerulonephritis #Kidney #MPGN #MedicalEducation #NKFClinicals @goKDIGO

@CMichaelGibson 🤣🤣🤣 a big no!

Will AI replace doctors? What say you ?

@DrNeilStone It also has MAOI activity …😉

MAHA "We need to get toxic chemicals out of food! " Also MAHA "Put methylene blue in your drinks" (PS - Don't put it in your drink. It's a dye)

SGLT2i can reduce the incidence of new-onset diabetes among individuals with cardiovascular or kidney disease. Read more in #EHJ 👉 bit.ly/4eMWqTe @RoccoMontone @ehj_ed #diabetes

@DrJacobsRad Great take. I consider these platforms (note I don’t call them AI) to be like a junior assistant.

Not what I was expecting to wake up to this morning. My qualifications include over 20 years as a radiologist, Canadian clinical lead on GE Healthcare's first commercial AI product, and president of the Ontario Association of Radiologists. Let's walk through this. 🧵 /1

@CBallantyneMD’s interest in preventive cardiology was inspired by his family’s history of heart disease. He knows that early interventions—like controlling LDL-C levels—can reduce the burden of cardiovascular disease and save lives. bit.ly/4gF9s7u

#Betablockers in #HFpEF: no evidence to support use, some evidence of undesirable effects Do you deprescribe #BBlockers in pts w #HFpEF, particularly given prevalence / burden of #chronotropicIncompetence? Could there be a role for #pacing HFpEF? #HFpEFBridgingDisciplines

Central limit theorem If the sample size is sufficiently large then the sampling distribution of the mean approximates a normal distribution, even if the underlying distribution from which the samples were drawn was not normal. 🔗…-publications.onlinelibrary.wiley.com/doi/10.1111/an…

V. interesting paper suggests statins cost effective for essentially all adults Given this work & recent results from @arjunmanrai @JamesADiao on issues w/ PREVENT vs PCE risk functions, is it time to move beyond risk-centric paradigm for statin allocation?

Early intensive lipid lowering therapy saves lives ❤️ 💊 💉 🔸 Strike while the iron is hot (immediately post event) 🔹 Follow patients up & communicate LDL goals to patient & primary care 🔸 Listen to concerns & educate the patient on the ‘legacy affect’ of LDL lowering LDL⤵️, earlier, longer 👉🏼 better outcomes @RACGP #MedTwitter #CardioTwitter #MedEd #FOAMed

Always love a good review… it’s like my homework is already mostly done ✔️

you can reverse heart disease and stabilise plaques