Andrew J Sauer MD

My top ten tips for graduating fellows and faculty entering and continuing “early career” as I am transitioning into “mid-career”. A thread:

💬 Editorial: In the VESALIUS-CV trial, evolocumab reduced major cardiovascular events in high-risk patients, including those with long-standing #diabetes, already receiving statins but not reaching LDL-C targets. ja.ma/49c3jNX

US nonprofit hospitals spent $7.8 billion on management consultants from 2009 to 2023, but contracts were not associated with meaningful changes in finance, operations, or quality of care. 🧵 ja.ma/4d46zfq

@CASivaram1 Great point!

@AndrewJSauer I wonder how ‘time alone’ is defined in the era of social media. Even folks who are ‘alone’ are connected the world through social media almost constantly. With both good and bad aspects attached.

Keep this in mind when you are my age, in the “messy middle” and it feels like you never have any personal time, and much of your time is consumed by work. Also, you don’t have to follow the trend if you want to follow a different path.

As a transplant program builder and previous medical director and as a transplant physician, I can assure you we indeed run into cases of rejection because patients run into insurance barriers, lapse in coverage, or other challenges paying for meds (I’ve seen patients cut their calcineurin inhibitors in half to save money by dragging out their pills available and then they end up with rejection). Are you living under a rock? Oh I know, you just are talking out of your lane and maybe should just STFU.

Willing to bet no one in the USA has had an organ transplant rejection because their transplant medications were not approved by an insurance company. And the U.S. does a lot more organ transplants / year than our Medicare for All Canadian neighbor.

🚨 ¿Cómo tratar la congestión en Insuficiencia Cardíaca Aguda (ICA)? Un nuevo meta-análisis en el @EHJ_CardioPharma analiza 25 ensayos clínicos (7,149 pacientes) para darnos respuestas claras sobre las estrategias diuréticas. 🏥💊

Evidencia emergente orienta a replantear el dogma histórico, y continuar explorando la utilización de cloruro de sodio para descongestionar de manera más segura y eficiente. Así es, sal para quitar sal 💁🏻‍♂️ JAMA Cardiology 2026 10.1001/jamacardio.2026.0938

Did you know all 4 pillars of quadruple GDMT for heart failure can be had for under $35/month via Cost Plus Drug (cash pay)? @gcfmd @SJGreene_md @mvaduganathan @BiykemB @ShelleyZieroth @GianluSava @safchat @ankeetbhatt @AndrewJSauer 💊 ARNI (sacubitril/valsartan) — $14.40 💊 BB (carvedilol) — $6.32 💊 MRA (spironolactone) — $5.89 💊 SGLT2i (dapagliflozin) — $8.36 Total: $34.97/month = ~$420/year Cost is no longer the excuse. #HeartFailure #GDMT #CardioTwitter

Me and Dad and first time golfing since I broke my knee. Felt great. Hit two greens in regulation. Beautiful day. Life is good today.

First randomized trial to show Ozempic reduces alcohol consumption in people seeking treatment for alcohol use disorder. Placebo-controlled, double-blind. Participants with BMI >30 kg/m2. thelancet.com/journals/lance… @TheLancet

New newsletter: MODERN FATHERHOOD WOULD BE UNRECOGNIZABLE TO A 1950'S DAD Compared to their Boomer parents, childcare time among Millennial dads has more than doubled. Compared to their Silent Generation grandparents, it’s nearly quadrupled. You will be hard-pressed to find any part of day-to-day modern life that has changed more in the last half-century than the way today’s parents—and fathers, in particular—spend their time. The new American dad is more present and more exhausted—but also, more satisfied with life. What's behind this half-century transformation? Today's piece combines history, economic analysis, and gorgeous charts galore from @AzizSunderji

Dr. Sanjiv Shah explains the H2FPEF score used to support clinical decision making. Watch “HFpEF Explained — Prevalence, New Advances, and How to Diagnose,” a new Double Take video, now available on our YouTube channel.

Cardiometabolic disease does not fit neatly into silos, and our care models should not either. I am proud that Saint Luke’s Mid America Heart Institute is part of the new CHROME initiative, a national multisite effort launched with the AMCP Research Institute to evaluate how comprehensive cardiometabolic care models work in the real world, including their clinical impact, operational structure, patient and provider experience, and economic value. This is exactly the kind of work the field needs. We already know that many evidence-based therapies can improve outcomes in obesity, diabetes, cardiovascular disease, kidney disease, and related conditions. The harder question is how to organize care so the right patients are identified earlier, treatment is started more effectively, multidisciplinary care is sustained, and health systems and payers can realistically support it at scale. CHROME is designed to help answer those questions. At Saint Luke’s Mid America Heart Institute, through the Michael & Marlys Haverty Cardiometabolic Center of Excellence, we have been committed to building and studying practical care models that improve diagnosis, treatment uptake, and long-term outcomes. Our participation in CHROME reflects that mission and gives us an opportunity to help shape the evidence base for what modern cardiometabolic care should look like. What makes this initiative especially important is that it goes beyond clinical endpoints alone. CHROME will also examine governance, staffing, referral pathways, treatment protocols, diagnostic workflows, patient experience, provider workflows, payer decision-making, and implementation barriers. That is where scalable care models either succeed or fail. I am grateful to partner with AMCP Research Institute, Lilly, Geisinger, and the Patient Advocate Foundation’s Patient Insight Institute on this effort. If we want to close the gap between evidence and execution in cardiometabolic care, this is the kind of work that matters. amcp.org/amcp-research-…

@sportsandcraft Not the same but ok lol

@AndrewJSauer I make $500k+ and live paycheck to paycheck after I put 80% into the market every 2 weeks

High income is not wealth. 40% of people making $500K+ still live paycheck to paycheck. So when people say its crazy to be within striking distance of early retirement, I hear this: “I can’t imagine freedom because I spent mine.” The real clown show is making half a million dollars a year and perpetually needing the next paycheck.

If you haven't had the chance to read this month's moving editors page by @robmentz - please take a moment to do so. onlinejcf.com/article/S1071-…

@BIDMC_Medicine @harvardmed @JenHoCardiology @BidmcCvi @BIDMC_Research Outstanding and so deserved!

Congratulations to Dr. Jennifer Ho on her promotion to Professor of Medicine @harvardmed! As Director of Research in our Division of Cardiovascular Medicine, she has been instrumental in empowering collaborative research to advance cardiovascular health 🌟 bit.ly/4sZJGjj

Today, in clinic, my biggest role is financial planner. The world we live in.

The Chiefs just went out and took care of the running back room for the next four years This kid is NASTY. 1400 yards 12 TDs last season. Is also a really good pass catcher and forced more missed tackles than even Love last season Welcome Emmett Johnson to Chiefs A+

@pnatarajanmd @harvardmed @Harvard @MGBResearchNews @CGM_MGH @mghcvrc @MGHCVFellows @broadinstitute @BroadMPG @BrighamMedRes @MGHMedicine @MGHHeartHealth Overdue but congratulations!

Grateful to share that I’ve been promoted to Professor of Medicine @harvardmed @Harvard. I am deeply thankful for my family, mentors, collaborators, and trainees who have carried me here.