Anna Mathioudaki

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Anna Mathioudaki

Anna Mathioudaki

@AnnaMathioudak1

Studying the role of the tumor microenvironment in tumor progression 🧠🩸 Postdoc @DKFZ @MoritzGerstung group | Previously PhD @EMBL

Heidelberg, Germany 가입일 Ocak 2019
506 팔로잉415 팔로워
Anna Mathioudaki
Anna Mathioudaki@AnnaMathioudak1·
Tissue organization is fundamental to how tissues function - yet in cancer such spatial patterns can progressively break down. Ever wondered how?! Check out our new study, where we investigate how lymphoma reshapes lymph node architecture 👀
EMBL@embl

A new study maps the organisation of immune & stromal cells in lymph nodes and shows its association with prognosis in certain lymphomas. This has implications for long-term prognosis in cancer patients & can potentially open up new therapeutic avenues. embl.org/news/science-t…

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Anna Mathioudaki
Anna Mathioudaki@AnnaMathioudak1·
A must-read (& must-use) if you work with spatial transcriptomics data! 🍳 Having used Segger myself on Xenium data from multiple tissues, I can say the transcriptome profiles are so much cleaner-a game changer🤩 Congrats @HeidariElyas!
Elyas Heidari@HeidariElyas

1/9 New preprint out! 🍳 Our team at @EMBL, @DKFZ, and @MSKCancerCenter built #segger—a fast, accurate cell segmentation tool for ST. It’s a transcript-to-cell link predictor that matches transcripts to their cell origins in a snap!

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Moritz Mall
Moritz Mall@MoritzMall·
Excited to share our first preprint with @zauggj @embl! We screened 1,296 transcription factors for repressors that block unwanted plasticity and found many putative tumour suppressors. PROX1 stands out as hepatocyte safeguard that prevents #livercancer. biorxiv.org/content/10.110…
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Department of Biomedicine
Department of Biomedicine@DepBiomedicine·
🚀 Big news! Prof. Dr. Judith Zaugg @zauggj will lead the 'Molecular and Computational Hematology-Immunology' group at @DepBiomedicine. Her research focuses on the molecular mechanisms behind diseases of the blood and immune system, using cutting-edge single-cell and computational techniques. biomedizin.unibas.ch/en/communicati… #Welcome2024 #welcometotheteam #MolecularMedicine #Hematology #Immunology #TeamDBM
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Moritz Gerstung
Moritz Gerstung@MoritzGerstung·
My former student @alex_w_jung used detailed health data from 6.7 million Danes to learn risk models for 20 cancer types. A massive data crunch of 60 million hospital visits, 90M diagnoses, and a total of 193M life-years between 1978 and 2018. thelancet.com/journals/landi…
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Anna Mathioudaki
Anna Mathioudaki@AnnaMathioudak1·
Check this out 🤯 1 mouse - hundreds of cancer clones & genotypes 1 readout - simultaneous genotype & phenotype information Talk about efficiency hm 😁 congrats to everyone!
Tschaharganeh Lab@tschaharganeh

0/ Preprint alert! 🚨 One step closer to solving the genotype ➡ phenotype puzzle in cancer! Led by @BreinigMarco, @LomakinAI, and @HeidariElyas, our novel approach, #CHOCOLAT_G2P 🍫, deciphers the impact of combinatorial alterations on tumor phenotypes and their environment.

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Kai Tan Lab
Kai Tan Lab@KaiTanLab1·
Excited to share the first spatially resolved multiomics atlas for human bone marrow, published today in @CellCellPress. twtr.to/cJ099. Wonderful collaborations with Ling Qin @LingQin6, Charles Nelson, Martin Carroll, Ivan Maillard, Vinohd Pillai @pillai_vinodh labs!
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Areeba Patel
Areeba Patel@AreebaSpeaks·
The @MoritzGerstung lab @DKFZ was on a retreat in the picturesque village of Reipertswiller this week. Lots of great brainstorming, new ideas, career advice and hiking ⛰️🥾 Watch out for all the cool science this year! 🧬🔬🗺️🤖👀 #CancerResearch #AI
Areeba Patel tweet mediaAreeba Patel tweet mediaAreeba Patel tweet mediaAreeba Patel tweet media
Reipertswiller, France 🇫🇷 English
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Anna Mathioudaki
Anna Mathioudaki@AnnaMathioudak1·
Constantly amazed by how much one can recover from just H&E tissue stains! Case in point: predicting PDL1 expression from H&E of solid tumors using deep learning 🔬
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Anna Mathioudaki
Anna Mathioudaki@AnnaMathioudak1·
So much more to come! For now - explore our scRNA-seq data and our gene regulatory networks here: apps.embl.de/allosct/ And feel free to reach out for more details! Thanks to all our collaborators @AryanKamal_ @LabTidow and everyone else! (11/11)
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Anna Mathioudaki
Anna Mathioudaki@AnnaMathioudak1·
💡Our study allowed to delineate compositional, transcriptional and functional characteristics of T cells associated with allo-HCT outcome. We establish GPR56 on CD8+ T cells as a hallmark of allo-transplantation, suggesting it as a dynamic marker for antigen-experience. (10/11)
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