Costa Lab
59 posts

Costa Lab
@CostaLabCrick
Biochemists & cryo-EM scientists studying chromosome replication @TheCrick
The Francis Crick Institute 가입일 Ekim 2022
135 팔로잉508 팔로워
고정된 트윗

Beautiful work! Congratulations 👏👏🎉🎉
Costa Lab@CostaLabCrick
How does ATP hydrolysis by MCM enable replicative helicase loading onto DNA? Find the answer in our latest article rdcu.be/d6D8D Congratulations to Agata Butryn, who spearheaded the entire project, Contributions from @GreiweJulia in the early days. 🎉❄️🔬🧬
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How does ATP hydrolysis by MCM enable replicative helicase loading onto DNA?
Find the answer in our latest article
rdcu.be/d6D8D
Congratulations to Agata Butryn, who spearheaded the entire project, Contributions from @GreiweJulia in the early days.
🎉❄️🔬🧬
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@Jacob_Lewis90 @MolHorizons @LMSpenkelink Fantastic news @Jacob_Lewis90 and @LMSpenkelink ! Well done!
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How do mitochondria replicate their DNA? 🧬 Excited to share that our lab, based at @MolHorizons and led together with @LMSpenkelink, has been awarded an ARC Discovery Project Grant to tackle this fundamental question! 🎉 Postdoc & PhD opportunities coming soon! #Science
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Our article "MCM double hexamer loading visualized with human proteins" published in Nature today! ❄️🔬🧬🎉🥳
Great collaboration with John Diffley's lab. Congratulations to Florian Weissmann, Julia Greiwe and all other authors! rdcu.be/d1F7m

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@TCR_Miller Congratulations to you, Tom, for conducting the key experiment that initiated the structural project!
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@CostaLabCrick Congratulations Alessandro and all the authors! Amazing structures! 🎊🎊👏👏
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Costa Lab 리트윗함

Our study on how the human MCM2-7 helicase is loaded onto replication origins 🧬 is now online @Nature! 🎉
Our findings reveal that unlike in yeast, human MCM loading does not require ORC6 and can occur through multiple pathways.
Read more here: rdcu.be/d1F6S
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Costa Lab 리트윗함

Great kickoff for the EMBO EMBL Replication symposium with amazing structural and functional insights into initiation, elongation and histone recycling 🧬♻️ @TyeBik @CostaLabCrick @BleichertLab @Speck_Lab Chistol @Lopes_Lab Méchali @YardimciLab 🙌
#EESReplication @EMBLEvents

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The γTuRC saga goes on!
This time, we used cryoEM to describe how CDK5RAP2 helps nucleating microtubules by activating the γTuRC nucleator.
Another tour de force led by @sernarina and Fabian Zimmermann and a fun collab with @LudersLab @IRBBarcelona.
authors.elsevier.com/c/1jpyq_Yv6zvB…

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Costa Lab 리트윗함

Looking forward to this!
Rafa F Leiro@rfleiro
A fantastic lineup of speakers for the "Machines acting on DNA and RNA" meeting at @CNIOStopCancer All things D/RNA! 🧬Replication + transcription + translation + chromatin + repair + processing🧬 May 28th to 30th, 2025 - Save the date! @OscarLlorcaCNIO @rfleiro @NogalesLab
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Costa Lab 리트윗함

⏰ Deadline approaching for #EESReplication ⏰
Submit your abstract by 13 August and find out about the latest breakthroughs in DNA replication 🧪🧬
📅 5 – 8 November
📍 EMBL Heidelberg and Virtual
➡️ s.embl.org/ees24-12

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@FMattiroli @Jacob_Lewis90 Thank you, Francesca! See you (and Jacob who's also reading this) soon in Cambridge!
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Congratulations to group leaders Snezhka Oliferenko and Alessandro Costa (@CostaLabCrick) on being elected as members of @EMBO 🥳
crick.ac.uk/news-and-repor…
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