Gilbert Greub

185 posts

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Gilbert Greub

Gilbert Greub

@GilbertGreub

Lausanne, Switzerland 가입일 Şubat 2013
259 팔로잉256 팔로워
Gilbert Greub
Gilbert Greub @GilbertGreub·
Des bactéries anciennes sur le continent américain rts.ch/audio-podcast/… Un projet collaboratif que nous avons publié dans Science, et qui apporte un éclairage nouveau sur l'origine et l'évolution de Treponema pallidum.
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Christophe Dessimoz
Christophe Dessimoz@cdessimoz·
Fantastic outreach project in the form of a board game by @unil colleagues. Reinforces Lausanne as the probable world capital of microbiology-themed educational games! (Cue @GilbertGreub’s MyKrobs mykrobs.ch/en/)
NCCR Microbiomes@NCCRMicrobiomes

Are you ready for Ba(c)ttle? Bacttle: a microbiology educational board game for lay public and schools | Journal of Microbiology & Biology Education journals.asm.org/doi/10.1128/jm…

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Jan-Willem Veening
Jan-Willem Veening@JWVeening·
We show mbPE can make single base pair substitutions, multiple substitutions, insertions and deletions. Basically all you need. There are still some limitations such as the max length of insertions (~50bp) and deletions (~127bp)
Jan-Willem Veening tweet media
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Jan-Willem Veening
Jan-Willem Veening@JWVeening·
For simple mutations and small insertions, selection efficiency is >90%!
Jan-Willem Veening tweet media
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Jan-Willem Veening
Jan-Willem Veening@JWVeening·
While DNA double strand breaks are a serious issue in eukaryotic systems, for smaller bacterial genomes that do not contain NHEJ, this is not necessarily a problem. Therefore we changed to a nuclease-based system which we called Make-or-break prime editing (mbPE).
Jan-Willem Veening tweet media
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