xue liu

Thrilled to be back in Europe after two years. Especially excited to attend the EMBL Symposium again, first time since 2019! Looking forward to great science and inspiring discussions. #EMBLSymposium #microbiology

Great job opportunity at The Center for Integrative Genomics, Lausanne University, Switzerland unil.ch/cig/en/home.ht… For a tenure-track Assistant Professor position. More details for how to apply are here nature.com/naturecareers/…

@ninatang_ @A_P_S_A @BCM_MSTP @BCMFromtheLabs @DanielCBrock you look awesome!

Amazing @A_P_S_A South Regional Meeting this year! It was a treat talking to undergrads about the work we do @BCM_MSTP @BCMFromtheLabs and providing mentorship/guidance on their next steps as future physician scientists. And huge shoutout to our amazing chair @DanielCBrock!

Short‐term #probiotic supplementation affects the diversity, genetics, growth, and interactions of the native gut #microbiome onlinelibrary.wiley.com/doi/full/10.10… #guthealth @wileymicrobio @WileyHealth @WileyBiomedical

Antibiotics that Kill Gram-negative Bacteria by Restructuring the Outer Membrane Protein BamA biorxiv.org/cgi/content/sh… #biorxiv_micrbio

The @EMBLEvents 2025 Courses and Conferences poster has had an update! If you're especially interested in training in #datascience #AIinScience #omics and #bioinformatics, take a look at the EMBL-EBI courses here: ebi.ac.uk/training/live-…

Tax1bp1 enhances bacterial virulence and promotes inflammatory responses during Mycobacterium tuberculosis infection of alveolar ... biorxiv.org/cgi/content/sh… #biorxiv_micrbio

Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @DjenetBousbaine led the charge... @Nature 1/55

A few notes of gratitude. First, many thanks to @brucegoldman for explaining this so clearly... 52/55 med.stanford.edu/news/all-news/…

Hello, I am looking for a #Postdoctoral researcher with experience in bacterial genetics and antimicrobial resistance. Please send me a CV and a brief summary of your lab experience! Thank you!

The good idea comes when one person feels comfortable enough to say something that might make them look stupid and their friend is open enough to recognize its potential.

Genome-wide CRISPRi-seq identified ferredoxin-NADP reductase FprB as a synergistic target for gallium therapy in Pseudomonas aeruginosa biorxiv.org/cgi/content/sh… #biorxiv_micrbio

Hope our work can contribute a bit to the research related to F. nucleatum.

x.com/biorxiv_micrbi… This collaboration work started 3 years ago and was mainly carried out by a master student Ling Liu, who never knew how to culture bacteria at that time.

All the tools developed in this study was shared via the WeKwikgene (wekwikgene.wllsb.edu.cn).

Additionally, we evaluate promoters with variable strengths with a luciferase-based reporter system in F. nucleatum, providing valuable insights for future gene editing studies in bacterium and contributing to our understanding of its pathogenesis.

By exploring the native plasmids from F. nucleatum, we identified new backbones for construction of shuttle vectors and established a dual-plasmid system for the first time, offering new avenues for genetic manipulation in this bacterium.

The conjugation-based DNA delivery to F. nucleatum was also established, and this strategy can bypass the requirement of MTase methylations.

We employed Pacbio sequencing and identified the active RM systems in F. nucleatum. Engineered intermediatory E coli strains to expression the Methyltransferases. Improved the transformation efficiency 1000 fold, reaching 5000 CFU per ug plasmids.

Fusobacterium nucleatum is well known to be related with various human diseases. However, efficient transformation was limited to a few strains for this bacterium.