MelenhorstLab
140 posts

MelenhorstLab
@MelenhorstLab
Multinational team focused on curing cancer with cell therapy & immuno-engineering. Product safety, efficacy, reproducibility, and affordability are key.
Cleveland, OH 가입일 Ocak 2022
141 팔로잉220 팔로워

We make it to the cover @NatureBiotech! the IL-10-CAR-T cells eradicate solid tumors! nature.com/articles/s4158… The IL-10-CD19-CAR-T cells have shown promising clinical results in several investigator initiated trials too. Stay tuned! #SOHC @myESMO @ASH_hematology
Nature Biotechnology@NatureBiotech
The November issue is live nature.com/nbt/volumes/42… On our cover, Zhao et al. show that expressing IL-10 in CAR T cells improves their mitochondrial function and therapeutic efficacy in multiple solid-tumor models go.nature.com/3vh5Bdv
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MelenhorstLab 리트윗함

👏 Congrats to Prof. @carlhjune on receiving the @AbarcaPrize! His pioneering work in CAR-T therapy has transformed cancer treatment. During my time in his lab, I had the chance to experience his inspiring vision and trust, for which I am deeply grateful.
abarcaprize.com/award-winner-f…

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Excited to share our latest work on an image analysis paradigm that combines cell state and morphology analyses of patient biopsies at single cell resolution to uncover clinically relevant head-and-neck #cancer phenotypes! @CellCellPress cell.com/cell/fulltext/… tweetorial👇

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MelenhorstLab 리트윗함

Super cool to see our work highlighted by @ACIR_org If you haven’t had a chance to check it out yet this is a great summary!
ACIR@ACIR_org
New insights into nivolumab-induced immunoediting bit.ly/403lMIZ @TylerAlban1 @xrtGenomics @GeneCollector
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@RongFan8 @MingLiLab @GruppSteve @carlhjune @Tang_Lab_EPFL @SU2C @SU2Cscience @Penn @parkerici Dream-team, Rong, and kudos also to Stand-up-to-cancer for funding this very exciting work!
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@MingLiLab Thanks to all the amazing collaborators @GruppSteve @carlhjune @MelenhorstLab @Tang_Lab_EPFL. And the long-standing support of our project by @SU2C @SU2Cscience , and @Penn team @parkerici center!
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Today is the day 🤩. Thrilled to share our @Nature paper on Th2 function, CAR-T, & 8-year remission!! Huge team effort w/@GruppSteve @carlhjune @MelenhorstLab @Tang_Lab_EPFL, kudos to my postdoc @Zhiliang_Bai nature.com/articles/s4158…
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@ElizSMcKenna @DrGopalIyer You’re discovered Dutch haute cuisine! Also try “verse haring “ and “kroket uit de muur” 😉
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Super excited to share the final publication of Spectra, fruit of the wonderful collaboration between
@russell_kunes and @science_wallet, a gene program factorization program that I hope will help many interpret and bring insight from their single-cell data -->
Nature Biotechnology@NatureBiotech
Supervised discovery of interpretable gene programs from single-cell data go.nature.com/460weRo
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North Korea tensions: Why is Kim Jong-un upping the pressure? Not so super, man! bbc.co.uk/news/world-asi…
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Nedd Brockmann: The man who ran across Australia in 47 days…
Superman.. bbc.co.uk/news/world-aus…
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We are looking for doctors who are interested in Hematology and Oncology Hospitalist positions @ClevelandClinic practicematch.com/CareerCenter/O…

Solon, OH 🇺🇸 English

@PaulosLab It’s on my lab’s must-read list, along with Zinkernagel’s 1997 geography of immune response review, the Paulos 2010 STM ICOS CAR paper, and the Klebanoff quorum sensing work. And of course let’s not forget the helpless CD8 T cell themes.. and many other impactful, older pubs
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‘Wolde ye bothe eate your cake, and haue your cake?’
-John Heywood, 1546
Uncoupling T-cell expansion from effector differentiation in cell-based immunotherapy pubmed.ncbi.nlm.nih.gov/24329803/
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Bioicons.com
Here is an alternative to BioRender that is TRULY FREE and actively maintained. Over 1500 vectorized images sorted by license type (all creative commons or MIT). Fully editable icons and soon they will launch an Inkscape library.
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I wouldn’t say “starting” but “advancing our understanding..”. Great progress with high translational potential! statnews.com/2022/10/04/why…
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Excited to share TEMPOmap, our new spatiotemporal transcriptomics method that integrates metabolic labeling with 3D in situ sequencing to simultaneously profile the age and location of individual RNA molecules led by @JingyiRen Haowen Zhou and @huzengHZ biorxiv.org/content/10.110…
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Cleveland Clinic is selected as the leading healthcare system in a new initiative to accelerate collaboration and innovation in quantum computing.
Developed by @ConnectedDMV, this hub leverages our partnership with @IBMResearch to advance medicine. cle.clinic/3UKK6dz
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