Rogan Grant

@other_st_nick @chicagodivediva Acceptable is a stretch

@chicagodivediva It’s an acceptable burger but I can’t believe how much people used to talk it up

Loving Small Cheval is a red flag

@biorxivpreprint Identity, ontogeny, and age-related changes in splenic white pulp macrophages in mouse and human spleen biorxiv.org/content/10.648… @Misharin_lab @NorthwesternU

Trump budget proposes $5bn cut to NIH whitehouse.gov/wp-content/upl…

If FDA does this, which is highly likely succumbing to pressure from RFK Jr, it crosses a new red line and, as far as I know, is unprecedented. Lifting a ban on drugs that are injected into the bloodstream without data for safety or efficacy, so they can be compounded and further promoted to Americans. @By_CJewett Gift link nytimes.com/2026/03/31/hea…

We are thrilled to introduce our 2026 Schmidt Science Fellows — thirty-two incredible scientists set to embark on the next step of their interdisciplinary journey with our support. schmidtsciencefellows.org/news/the-2026-… @schmidtsciences

Cell-type-specific transposable element demethylation and TAD remodeling in the aging mouse brain biorxiv.org/content/10.110…

There's no reason to confirm RNA-seq results with RT-PCR

Nature research paper: Human hippocampal neurogenesis in adulthood, ageing and Alzheimer’s disease go.nature.com/4rzXpxb

Single-nucleus transcriptomics of an engineered pig model reveals microglia–T cell interactions driving Huntington’s disease neurodegeneration go.nature.com/4aUhuaD

1/ 🧵 No, you do not always Need Single-Cell RNA-seq Single-cell RNA-seq is popular and powerful, but it's not always the best choice. Here's why you should think carefully before diving in.

A calcium channel named Orai1 present in immune cells called #microglia may explain how neuroinflammation can induce depressive-like behaviors, according to new experiments in mice published in @SciSignal. scim.ag/4aEj0O3

Excited to share VIPerturb-seq! New tech from my lab which aims to improve the cost, data quality, and efficiency of single-cell CRISPR screens so that they are accessible to any lab - even at genome-wide scale Preprint and 🧵 (1/): biorxiv.org/content/10.648…

DEPower: approximate power analysis with DESeq2 biorxiv.org/content/10.648…

Northwestern has launched the Simpson Querrey Brain Health Institute 🧠 The new institute, made possible with nearly $25 million in support from University Trustee Kimberly K. Querrey '22, '23 P, seeks to preserve brain health across the lifespan. spr.ly/6013hM4MS

Disgraceful from @SciTechAction and all the scientific societies and universities that back them. Thanking the GOP reps and senators for bucking the administration to defend science funding, ok. But genuflecting to a president whose budget would have gutted research funding is obscene.

How hard could it really be to live without an @amazon account? I mean...hard yeah, but maybe worth it?

Notice of Temporary Extension of Eligibility for the NIH Pathway to Independence Award (K99/R00) grants.nih.gov/grants/guide/n…

Over the course of a lifetime, we face only a few moments where the decisions we make and the actions we take will shape our history for years to come.  This is one of them.

Excited to share our new @NatImmunol paper mapping the immune microenvironment and TCR repertoire in the border of the human degenerating brain using scRNA/TCR-seq and spatial proteomics @RyanMHobson @bradshaw2280 nature.com/articles/s4159…

NEWS Gregory Bovino has been removed from his role as Border Patrol “commander at large” and will return to his former job in El Centro, California, where he is expected to retire soon. Full Story: bit.ly/4t1tm2L