Dylan Wheeler

This is my new favorite video explainer. Watch to discover our problem. Reflect to understand why #Bitcoin is the solution. Fix the money, fix the world. Thank you @satsvsfiat 🙏

Just discovered this cool account Live posting from 25 years ago, and they also have ones going for 50, 100, and 250 years ago Especially looking forward to 250 in July!

@tesla_na Batteries at scale 👨‍🍳

Our Lithium Refinery ushers in energy independence for North America Regionalized access to critical battery minerals brings jobs, cuts emissions & helps accelerate our mission

This is what a currency collapse looks like On January 9, the Iranian rial lost 99% of its value within hours After the collapse, the entire price history of #Bitcoin denominated in IRR becomes almost a flat line Bitcoin went from a hedge to a lifeboat overnight

Come build in New Hampshire. I’ll help you move. No state sales, income, dividend, capital gains, or estate tax. Just property tax. 📍Near Boston and NYC. ⚕️Right to Try (medical) ☢️56% of energy from nuclear 💜Politically balanced We’re building Freedom Village — a new neighborhood for entrepreneurs to live

Most of NH's School Administrative Units (SAU) now pay their superintendent more than the Governor while property taxes keep climbing. We mapped every town. Read the full breakdown and explore the interactive map ⬇️ livefreepressnh.com/post/most-scho…

Today we @a16z are announcing American Dynamism Fund II! Together with Fund I, we have raised a total of $1.776 billion to invest in companies advancing America’s national interest. Happy 250th birthday, America! It's time to build.

Stack Overflow has seen the number of monthly questions on its platform collapse from 300k to ~0 since launch of ChatGPT. But annual revenue is acrually up 2x over that span to $115m. How? It has licensed its back-catalog of human answers to AI labs and created an enterprise product called “Stack Internal”, a GenAI tool powered by millions of its Q&A (currently used by 25,000 companies).

A brilliant new article by Saloni. We can now develop vaccines in weeks, designed atom-by-atom, and manufacture billions of doses of them within months. We are protecting against more and more diseases faster and faster. The golden age of vaccines is now.

This season, homes become more than assets. Kitchens get louder. Living rooms fill. Traditions repeat. We think about housing the same way: built for real life and held long term. Grateful for our partners, residents, and communities. Wishing everyone a warm holiday season!

the act of creation is the only thing that justifies existence

@typesfast Fahrenheit is how a human feels, Celsius is how a water feels, and Kelvin is how an atom feels.

One of my favorite quotes is the one from Marcus Aurelius: ‘The happiness of your life depends upon the quality of your thoughts.’ I think it’s always good to remember it.

Poor guy has never ridden a bike down a big hill before

The best conversations are the ones that make you look up from the spreadsheet model and wonder: What if? Grateful for friends who keep that instinct alive Appreciate the shout 🙌 let’s keep building

Man is made to create, not retire

Capitalism doesn’t assume humans aren’t greedy. It assumes they are and refuses to give them power over others. That’s the point. Greed under capitalism is constrained by consent. You only get richer by offering something others voluntarily choose to pay for. If you stop providing value, the money stops. Greed under collectivism is unconstrained. It’s backed by force. You get resources whether you create value or not, so long as you can moralize need or capture political power. Also, capitalism doesn’t pit competition against cooperation. Competition is how we discover who can cooperate best. Every successful business is a massive act of cooperation with customers, workers, suppliers, and investors. It just isn’t coerced cooperation. And the claim that capitalists never give back is empirically false. Private charity, philanthropy, reinvestment, and voluntary aid explode under capitalist systems and collapse under socialist ones. What you’re really saying is this: You don’t trust individuals to choose generosity. You trust the state to enforce it. That isn’t moral. It’s just replacing voluntary cooperation with compulsory obedience.

NSF is launching one of the most ambitious experiments in federal science funding in 75 years. The program is called Tech Labs, and the goal is to invest ~$1 billion to seed new institutions of science and technology for the 21st century. Instead of funding projects, the NSF will fund teams. I’m in the @WSJ today with a piece on why this matters (gift link): wsj.com/opinion/scienc… Here’s the basic case: 1) Most federal science funding takes the form of small, incremental, project-based grants to individual scientists at universities. 2) The typical NSF grant is ~$250k/year to a professor with a couple of grad students and modest equipment over a few years. This is a perfectly reasonable way to fund some science, but it's not the only way. 3) A healthy portfolio needs more than one instrument. Project-based grants are like bonds: low-risk, steady, safe. But no one trying to maximize long-run returns would put 70% of their portfolio in bonds. 4) Yet that's basically what our civilian science funding portfolio looks like. Around 3/4ths of NSF and NIH grant funding is project-based. 5) Tech Labs is NSF's attempt to diversify that portfolio. The Tech Labs program is aiming for: - $10-50 million/year awards per team - 5+ year commitments - Measuring impact through advancement up the Tech Readiness Level scale rather than papers published - Up to ~$1 billion for the program - Supporting research orgs outside traditional university structures 6) Scientific production looks very different than it did when the NSF launched 75 years ago. The lone genius at the chalkboard can only do so much. Frontier science + tech today is increasingly team-based, interdisciplinary, and infrastructure-intensive. 7) The team behind AlphaFold just won the Nobel Prize in Chemistry. It came from DeepMind, an AI lab with sustained institutional funding and full-time research teams. It would be near-impossible to fund this kind of work on a 3-year academic grant. 8) Same pattern at the @arcinstitute (8-year appointments, cross-cutting technical support teams) and @HHMIJanelia (massive infrastructure investments to map the complete fly brain). Ambitious science increasingly needs core institutional support, not a series of project grants stapled together. 9) Similarly, Focused Research Organizations (@Convergent_FROs) have showcased a new model supporting teams with concrete missions and predefined milestones to unlock new funding. 10) There’s a whole ecosystem of philanthropically-supported centers doing amazing research, like the Institute for Protein Design, the Allen Institute, the Flatiron Institute, the Whitehead Institute, the Wyss Institute, the Broad — the list goes on. 11) But philanthropy can’t reshape American science alone. The federal government spends close to $200 billion each year on research and development, an order of magnitude more than even the largest foundations. 12) If we want to change how science gets done at scale, federal funding has to evolve. And the NSF and NIH don’t have dedicated funding mechanisms to support or seed these sorts of organizations. 13) Earlier this year, I started working on a related framework called “X-Labs” that built on all this exciting institutional experimentation that’s been happening within the private and philanthropic sectors. It’s time for the federal government to step into the arena: rebuilding.tech/posts/launchin… 14) Traditional university grants are still important for training the next generation of scientists and for certain kinds of curiosity-driven work. But after 75 years of putting nearly everything into one model, we should try something different. 15) And key program details are still being developed! You can reply to the Request for Information with suggestions or feedback on how to design this program here: nsf.gov/news/nsf-annou… 16) Science is supposed to be about experimentation. Science funding should be too.

When I was younger, my father gave me similar advice: “The only thing people will remember about you is whether you were there for them in their moment of need.” Pound for pound probably the best advice I’ve ever received