Angers Lab

Warmest congratulations to Milena who defended her PhD thesis on Oct 13, 2023. Milena used phenotypic CRISPR screens to identify new regulators of Hedgehog signalling during neural development.

Congrats to Sofia who graduated with her MSc on August 30th. Sofia examined the effects of a novel Frizzled agonist on blood brain barrier permeability.

Registration is now open! The 2023 GRC on Wnt signaling is scheduled for July 30 - August 4, 2023 at Rey Don Jaime Grand Hotel, Castelldefels, Spain. The associated GRS is scheduled for July 29 - July 30 at the same location. @TalksWnt @GordonConf grc.org/wnt-signaling-…

The Angers lab 2022 Summer Picnic was held at Riverdale Park and was a success! Toronto summers are amazing. @DonnellyCentre

Super proud of Dr. Pierre Thibeault @frenchnerd who received a CIHR fellowship for his work unravelling mechanisms underlying Wnt signalling in endothelial cells. Super well deserved! @angerslab @DonnellyCentre

"It’s a fantastic place with enormous possibilities" - @UofT Professor Stephane Angers outlines his scientific vision for the Donnelly Centre as its incoming director from Sep 1. Learn more from this great piece by @blakeeligh @uoftmedicine bit.ly/Angers_intervi…

Following the cancellation of the 2021 Wnt Gordon Research Conference, many people from the Wnt community asked whether there would be a "virtual Wnt meeting" or an opportunity to present talks online... 1/n

Brain tumours might be spurred by an injury, Donnelly Centre investigators & colleagues @SickKidsNews @PMResearch_UHN have found. The research out in @NatureCancer opens up new ideas about the origin of #glioblastoma and how to combat it. Read our story: bit.ly/NatureCancerGl…

Out now in @NatureCancer: rdcu.be/cc2DJ. On track from developmental to injury response state, GBM stem cells get derailed (we think by pre-existing mutations or CNVs) and begin churning out bulk cancer cells. Hunting now for pre-GSC cells that lie dormant until injured

We are thrilled to welcome Dr. Pierre Thibeault @frenchnerd who is joining the lab as a PDF on Jan 4,2021. Pierre completed his thesis in the Ramachandran lab @RayWyke at Western.

New work from the lab identifies a new mechanism of bcatenin nuclear import in colorectal cancer cells. Beautiful study by the talented @monika_mis

@UofTPharmacy @uoftpharmsci @MbD_UofT

Congrats to Elli @elli_kub for a successful MSc defense. Good stuff!

New pub from the lab, collab with Sidhu: doi.org/10.7554/eLife.… where we describe a new Ab modality mimicking Wnt proteins and enabling selective activation of Frizzled receptors. Congrats to all involved : @monika_mis @Zachs24 @chidiacrony @elli_kub @siobhanob29

Congrats to Monika who successfully defended her PhD thesis!

Nishani defending her thesis today! Beautiful work on Glioblastoma stem cells !

Celebrating Nishani’s Genes and Development paper with the lab!

AP Exclusive: First gene-edited babies claimed in China apnews.com/4997bb7aa36c45…