Sarah Offley
103 posts
Sarah Offley
@offley_sarah
Penn Genetics PhD candidate in @GardiniLab interested in transcriptional regulation, cell fate, and finding the best sushi in Philly. @PittBioSci BS. she/her
가입일 Temmuz 2019
259 팔로잉150 팔로워
It’s happening!!! Come to Wistar tomorrow at 1:30 to hear about all things eukaryotic transcription 🥳🥳🥳
CAMB Graduate Group@CAMBUpenn
Sarah Offley (@offley_sarah) in the @GardiniLab defends her thesis tomorrow!
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Sarah Offley 리트윗함
@sciencesheri @CellGenomics Major congratulations, Sheridan!!
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My functional validation of a causal variant at the FAIM2 obesity GWAS locus is out today in @CellGenomics! (1/4) cell.com/cell-genomics/…
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So honored to have received this award!! Major shoutout to everyone at Wistar, the Gardini lab, and the Penn G&E grad group for their unwavering support and belief in me throughout my PhD.
The Wistar Institute@TheWistar
Congratulations to predoctoral trainees Sarah Offley, in the Gardini Lab, and Davide Maestri, in the Tempera Lab, for sharing the 2023 Monica H. M. Shander Fellowship Award for their outstanding research. Wistar is proud of our future scientific leaders in training!
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@TemperaLab @GardiniLab Thank you, Italo!! Couldn't have gotten this far without the incredible support system at Wistar. Major congratulations to Davide!!!! 🎉
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Sarah Offley 리트윗함
My labmate’s (and good friend’s) thesis defense is tomorrow!!! Be there or be square 🥳🤓👨🔬
Connor Hill@connor_m_hill
Very excited to be defending my thesis tomorrow! If you would like to attend either in person it will be taking place in Austrian Auditorium in CRB at 2pm EST and if you can't make it in person it will also be on zoom pennmedicine.zoom.us/j/92778850074
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Sarah Offley 리트윗함
“Ten years ago I was kicked out and forced to retire.”
Our new medicine laureate Katalin Karikó (@kkariko) told us how much it means to be awarded the Nobel Prize after a scientific career that has been full of challenges.
Ten years ago, Karikó was still doing all her experiments by hand but today she has been awarded the medicine prize for her research on mRNA, which led to the development of COVID-19 vaccines.
Listen now:
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So proud of my bestie, old roomie, and classmate!!!!!!!!! What a shining star!!! 😍😍 Congratulations to all involved
Bailey Warder@BaileyWarder
I’m so excited that my thesis work from @SDFlies lab is finally out in the world! We address how a stem cell niche forms, and how niche shape impacts its function. Additionally, we show that stem cells aid in shaping the niche that guides their behavior biorxiv.org/content/10.110…
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Sarah Offley 리트윗함
Our latest story on how R-loops and G-quadruplexes influence genome organization is finally out today in @MolecularCell!
G-quadruplexes associated with R-loops promote CTCF binding: Molecular Cell cell.com/molecular-cell…
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Sarah Offley 리트윗함
I am very happy to share our newest results characterizing the novel Integrator subunit INTS15 (C7ORF26). It was an exciting collaborative effort of @WojtekGalej and lab with the @GardiniLab and in particular my amazing co-author @offley_sarah!
Cell Reports@CellReports
A combinatorial approach to uncover an additional Integrator subunit dlvr.it/SktD5q
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MY OLD ROOMIE IS A SUPERSTAR 🤩
Sarah Offley@offley_sarah
What started out as a mystery cloning project during my rotation turned out to be the 15th Integrator subunit and my first, first author paper! From @GardiniLab and @WojtekGalej labs, we use a combo of AlphaFold2, proteomics, and functional genomics to characterize INTS15
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@GardiniLab @WojtekGalej Major shoutout to my co-first author @MorPfl and everyone in the Gardini and Galej labs for their help through this process!
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What started out as a mystery cloning project during my rotation turned out to be the 15th Integrator subunit and my first, first author paper! From @GardiniLab and @WojtekGalej labs, we use a combo of AlphaFold2, proteomics, and functional genomics to characterize INTS15
Cell Reports@CellReports
A combinatorial approach to uncover an additional Integrator subunit dlvr.it/SktD5q
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Sarah Offley 리트윗함
What can machine learning do for your favorite protein complex? A lot! Especially if paired with proteomics and genomics. In collaboration with @WojtekGalej we characterized the 15th Integrator subunit! Shout out to @offley_sarah and @MorPfl for leading this effort #transcription
Cell Reports@CellReports
A combinatorial approach to uncover an additional Integrator subunit dlvr.it/SktD5q
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Sarah Offley 리트윗함
A combinatorial approach to uncover an additional Integrator subunit dlvr.it/SktD5q
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Sarah Offley 리트윗함
Interested in how the Integrator complex regulates #transcription, #RNA processing, #chromatin landscape and DNA repair? Check out this recent #NRMCBReview, written by the @GardiniLab @TheWistar 🥳
go.nature.com/3CHEv0y
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Sarah Offley 리트윗함
Great to see this finally published in @Dev_journal!
journals.biologists.com/dev/article-ab…
Great effort by my postdoc @evodevomocracy, my student @SamBarnada, in collaboration with @jisaacmurray and his team! (And many thanks to @Y_Gilad for the chimp iPSCs!)
Marco_Trizzino Lab@marcotrizzino
New preprint from my lab is out! We used human and chimp iPSCs, along with functional genomics, to study the evolution of hippocampal neurogenesis, focusing on a specific progenitor population seemingly involved with human-specific increase in hippocampal volume 1/n
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