@johnrich I don’t see that recommendation on the NIH sit. The screenshot says the links are evidence reviews it recommended therapies. I’m not sure this person has it right.
@EricTopol@JAMA_current They do examine that. The PRS did not perform well as a stand-alone tool or improve the pooled cohort equations (used to guide statin initiation). Hence, they do not provide additional guidance for statin initiation. @venkmurthy