Aaltonen Lab

We are excited to share new results from Vilja Jokinen et al. @AaltonenLab "Activation of FGFR genes by genetic and epigenetic alterations in uterine leiomyomas" nature.com/articles/s4427…

Is it clinically relevant to differentiate between different causes of the same mutations? Samantha Martin and Kristiina Rajamäki @AaltonenLab explore the different sources of common mutations in colorectal cancers to look for clues. tumorgenetics.blog/2025/03/18/eve…

New Paper Published! nature.com/articles/s4138…

Congratulations to Lauri Sipilä for his defense and completion of his PhD! His thesis "Finnish Healthcare Registries in the study of Cancer Etiology" was carried out in the Aaltonen group with active collaboration with the Finnish Cancer Registry. Well done Lauri! #PhD

New Blog from the Nykter group, @CoEinTG is out! #spatialtranscriptomics #cancerresearch tumorgenetics.blog/2024/12/12/eat…

Päivi Nummi, a PhD student with @AaltonenLab, will present their work, ‘Cancer and mobile DNA’, during an Afternoon in the Science Basement. When: 11th of December, 2024 at 17:30-19:00 Helsinki time (EEST) Where: Oodi Library, 3rd floor Saarikoski (Töölönlahdenkatu 4, Helsinki)

Onneksi olkoon Sini! @Sini_74

Lauri Aaltonen accepts the Jahre Award for #MedicalResearch at the University of Oslo. Professor Aaltonen and Professor Helleday (Karolinska) share the Award for their discoveries of mechanisms that contribute to #cancer development in humans. photo credit: Jarli&Jordan/UiO

New Blog from the @CoEinTG "Transcription Factor Footprinting with Fiber-Seq"! @helsinkiuni @HelsinkiUniMed #tumorgenetics tumorgenetics.blog/2024/11/08/tra…

New Paper published! Cancer incidence following non-neoplastic medical conditions: a prospective population-based cohort study (Lauri Sipila et al). @CancerRegFi @CoEinTG medicaljournalssweden.se/actaoncologica…

There's a new blog from the CoE in Tumor Genetics! "On our way to understanding the treatment resistance of Prostate Cancer" #ProstateCancer tumorgenetics.blog/2024/10/15/on-…

New blog from the Center of Excellence in Tumor Genetics! Studying the Regulatory Genome by Maritta Räisänen of the Aaltonen Lab @HelsinkiUniMed @helsinkiuni

Congratulations to Samantha Martin et al for the published paper in Human Molecular Genetics! academic.oup.com/hmg/advance-ar… #lynchsyndrome #colorectalcancer

Huge congratulations to Professor Lauri Aaltonen for receiving the 2024 Anders Jahre Award for Medical Research! aka.fi/en/about-us/wh…

Now out @Nature, our paper on HiDEF-seq: single-molecule DNA sequencing that resolves single-strand changes (mismatches and damage)! go.nature.com/3KG7Njh

Lynch syndrome carries a significant increase in a person's cancer risk. In a paper published this month, Lauri Sipilä et al. have demonstrated the use of genetic and clinical data to identify those at risk of disease. link.springer.com/article/10.100… @AaltonenLab @FinnGen_FI

Untangling the factors that increase the risk of cancer is difficult. Karri Seppä from @CancerRegFi helps clarify the impact of exposures on cancer risk in our latest blog post. tumorgenetics.blog/2024/06/07/sub…

New paper from the Cancer regulation and Immunology group @RautajokiLab published in @SciReports! Reporting risk variants associated with familial glioma in Finland. Collaboration with Aaltonen lab and @NykterLab from the @CoEinTG. nature.com/articles/s4159…

Congratulations to Lauri Sipilä et al. @AaltonenLab for their recently published work on mutational signatures in sinonasal adenocarcinoma genesenvironment.biomedcentral.com/articles/10.11…

The annual meeting of the @CoEinTG was organised in scenic Hämeenlinna. Two days were filled with inspiring presentations, including by our PI @KirsiRautajoki and workshops. It is always a pleasure to meet our colleagues from Taipale Lab, @NykterLab @AaltonenLab and @CancerRegFi!