Adrien Leger

2K posts

Adrien Leger banner
Adrien Leger

Adrien Leger

@AdrienLeger2

Director of Modified Bases Research at @nanopore. Moving slowly to where the sky is less depressing. https://t.co/U30YEgDbsO

Oxford, England Katılım Eylül 2014
233 Takip Edilen855 Takipçiler
Sabitlenmiş Tweet
Adrien Leger
Adrien Leger@AdrienLeger2·
🚨 We’re hiring ! 🚨 Join our cutting-edge research team as a molecular biologist at @nanopore HQ in Oxford. Perfect for a fresh PhD or MSc with a couple of years’ experience. Work at the interface of chemistry, molecular/synthetic biology and AI 👉 ejnh.fa.em2.oraclecloud.com/hcmUI/Candidat…
Adrien Leger tweet media
English
0
8
14
1.4K
Adrien Leger retweetledi
Marcus Stoiber
Marcus Stoiber@Stoibs11·
Dorado 1.0 🚀release with new RNA modified base models for 2’Ome as well as improvement of all DNA and RNA modified base models including massive improvement in 6mA for open chromatin prediction! Also a lot more non-mods related features😆! #NanoporeConf github.com/nanoporetech/d…
Marcus Stoiber tweet mediaMarcus Stoiber tweet media
English
2
13
28
2.7K
Adrien Leger retweetledi
Daniela Bezdan
Daniela Bezdan@Daniela_Bezdan·
Tweet 1/2 WOW—2’O-methylation detection in direct RNA-seq is here! A breakthrough for RNA therapeutics, viral evasion, and mRNA stability. Oxford Nanopore now enables single-base resolution of RNA mods like 2’OMe-A/C/G/U directly from native RNA. #nanoporeconf @nanopore @NanoporeConf
Daniela Bezdan tweet mediaDaniela Bezdan tweet media
English
1
4
12
893
Adrien Leger retweetledi
Rahmat Kemal 🍉
Rahmat Kemal 🍉@RAKemal·
ONT @nanopore is the only sequencing tech capable of direct RNA seq (without cDNA conversion step). Not only that, ONT can detect RNA modifications in the nucleotide bases and sugar! #Nanoporeconf
Rahmat Kemal 🍉 tweet mediaRahmat Kemal 🍉 tweet media
English
1
1
5
447
Adrien Leger retweetledi
Jonathan Jacobs 🧬🦠🕹️🏕️
Jonathan Jacobs 🧬🦠🕹️🏕️@bioinformer·
Who has DNA methylation on ~5,000 microbes sequenced w/@nanopore? We do! Who’s working hard on getting this data out before #ASMicrobe in LA next month? We are!🙃 Stay tuned! Major updates coming ATCC Genome Portal starting w/methylation data on 1000’s of microbes! #Genomics
English
1
11
32
2.2K
Adrien Leger retweetledi
Chris Seymour
Chris Seymour@iiSeymour·
Dorado is 1.0! 🎉 This London Calling release updates our DNA and RNA models to v5.2 with a new suite of mod models that are higher accuracy, lower FP rates, and significantly faster. - Introducing dorado variant 👀 - HAC error rate is down over 25%. - New 2’Ome mod models - Hopper & Blackwell SUP speed ups #Nanoporeconf
English
4
26
84
5.3K
Adrien Leger retweetledi
Nathan 🧬
Nathan 🧬@nathanbaggers·
Excited about @nanopore's collaboration with @uk_biobank to create the first comprehensive epigenetic map of the human genome. Thrilled to see work from our team (@Stoibs11, @AdrienLeger2, @ArtRand ) driving such pivotal advancements!
Oxford Nanopore@nanopore

We are proud to announce a collaboration with @uk_biobank to create the world’s first large-scale #epigenetic dataset of 50k participants. The dataset will unlock crucial insights into how #epigenetics drives disease & the breakthroughs to treat them. bit.ly/4g34RuK

English
1
9
30
5.9K
Adrien Leger retweetledi
Heng Li
Heng Li@lh3lh3·
The latest hifiasm can directly assemble standard @nanopore simplex R10 reads, without HERRO correction or other preprocessing, to phased contigs of contiguity comparable to HiFi assembly. Like before, you can further add ultra-long, Hi-C or trio data for better assembly.
Mike Vella@vellamike

Exciting news! The latest hifiasm release from @ChengChhy and @lh3lh3 adds beta support for @nanopore simplex R10 reads. Initial results look very promising. 🚀 Check it out: github.com/chhylp123/hifi…"

English
2
57
183
22.3K
Adrien Leger
Adrien Leger@AdrienLeger2·
We have been busing working on research models to detect all 2'Ome-RNA modified nucleotides on top of PseudoU, m6A, m5C and Inosine using @nanopore dRNA seq. Preliminary results on Human #rRNA are very exciting. See🦋for more details bsky.app/profile/adrien…
Adrien Leger tweet media
English
0
6
14
1.6K
Adrien Leger retweetledi
Libby Snell
Libby Snell@Libby_Snell_·
I am absolutely thrilled to be back in Kanazawa, Japan (a fave!), for the #tRNA2024 conference! It was my pleasure to present recent updates for @nanopore #directRNA sequencing, including our ever-expanding mod base seq offerings to this very keen audience! #tRNA #RNAmods
Libby Snell tweet mediaLibby Snell tweet mediaLibby Snell tweet mediaLibby Snell tweet media
Kanazawa-shi, Ishikawa 🇯🇵 English
0
1
17
983
Adrien Leger
Adrien Leger@AdrienLeger2·
It's Christmas in advance with a very special @nanopore #opendata release ! 🎅 Today we are releasing our 5mC 5hmC and 6mA DNA mod synthetic control datasets with each mods in all possible 5 mers contexts. All nicely wrapped in a comprehensive validation blog post.🎁
Marcus Stoiber@Stoibs11

New blog: Modified Base Best Practices & Benchmarking for @nanopore 🧬 sequencing Includes: * Raw POD5 files for synthetic ground truth strands * Modified base calling best practices * Modkit recommendations Check it out: labs.epi2me.io/mod-validation… #methylation #bioinformatics

English
0
13
35
3.4K
Adrien Leger retweetledi
Prof. Nikolai Slavov
Prof. Nikolai Slavov@slavov_n·
The epitranscriptome formed by the growing number of modifications occurring within mRNA transcripts.
Prof. Nikolai Slavov tweet media
English
11
243
1.1K
126.2K
Adrien Leger retweetledi
Rosemary Sinclair Dokos
Rosemary Sinclair Dokos@RosemaryDokos·
Low coverage (5x) @nanopore data vs methylation arrays delivers far more data. Great talk by the wasatch team at #ashg2024.
Rosemary Sinclair Dokos tweet media
English
0
6
31
4.6K
Adrien Leger retweetledi
Oxford Nanopore
Oxford Nanopore@nanopore·
Methylation calling made easy—just #SwitchON. Direct nanopore sequencing captures methylation and characterises genetic variation simultaneously and without bias. Get the clarity you need to reveal more biology. What you’re missing matters:nanoporetech.com/wymm?utm_campa… l&utm_source=twitter #WYMM More at #ASHG24
English
1
3
5
1.4K

Keşfet

@nanopore @NanoporeConf @uk_biobank @Stoibs11 @ArtRand @logan_mulroney @MattiaPelizzola @elonmusk