Aina Mª Mas Calafell

Can distinct repressive histone PTMs substitute for one another? We found that H3K9me3 and H3K36me3 can only partially compensate for loss of H3K27me3 nature.com/articles/s4146… @NatureComms @helin_kristian @LinHedehus Our results support the concept of a combinatorial histone code

📢 Progress from Cima: researchers develop ELATUS, a tool that detects long non-coding RNAs (lncRNAs), key in diseases such as cancer. 🔬 We detected the lncRNA AL121895.1, essential in breast cancer proliferation. 🔗 More details 👇 cima.cun.es/actualidad/not…

🧬 We’re excited to introduce D&D-seq, a single-cell technology that maps DNA:Protein interactions through molecular footprinting.. Check it out here: biorxiv.org/content/10.110… #Genomics #Epigenetics

Thrilled to announce that ELATUS is out in @NatureComms! ELATUS uncovers functional lncRNAs in scRNA-seq missed due to poor annotation, such as AL121895.1, involved in breast cancer, providing insights into lncRNA biology. @MaiteHuarteLab @mikelhernaez nature.com/articles/s4146…

Queremos contaros que La Fundación para el conocimiento Madri+d @madrimasd ha otorgado a @dcienciablog uno de sus premios de Ciencia en Español. ¡Muchas gracias por el reconocimiento! Gracias a todos los científicos que habéis colaborado con nosotros y a nuestros lectores.

Europa financia con 1,5 millones la investigación de Guillem Ripoll, profesor de @EconomUnav. Ha recibido la beca 'Starting Grant' del @ERC_Research para analizar y prevenir el comportamiento iliberal en la administración pública. #ERCStG 👉 unav.edu/noticias/-/con…

🚨 Paper Alert! 🚨 Does RNA regulation impact the p53 pathway and DNA damage response? We reveal distinct m6A-dependent and independent functions of the YTHDC1 protein. Proud of the work by @BlazquezElvira @CIMA_unav, collaboration with @raimondi_ivan @nygenome 🔗 Read here 👇

Do you want to know how we're using #AI to fight cancer? Join us in the pub at the ICR's @pintofscience to hear our researchers talking about their work. 📅15 May 📍The Prince Albert Battersea SW11 4PF 🗣️@stephensammut & @boragurel Book now: pintofscience.co.uk/event/using-ai… #Pint24

Thrilled to finally share this work! @MaiteHuarteLab and I delve into the interplay between RNA regulation and DNA damage finding that "YTHDC1 m6A-dependent and m6A-independent functions converge to preserve DNA damage response"! biorxiv.org/content/10.110…

A must read!!! Congratulations @kike411

Happy to share our latest paper in @NatureComms ! #lncRNA lncREST and its role in #replicativestress. Take home: lncREST associates to the stressed replication forks to recruit replication proteins to sites of DNA replication! @MaiteHuarteLab rdcu.be/dxyMK A 🧵:

📢 Paper alert! Can a chromatin-associated lncRNA impact replication stress? Dive into the details of how lncREST localizes at stressed replication forks and enhances the assembly of fork signaling factors. Work led by ⭐️@LuisaStatello nature.com/articles/s4146…

@dcienciablog @CIMA_unav @NatureComms dciencia.es/el-arn-nacient…

Científicos españoles han descubierto que el ARN que se está “fabricando” es capaz de regular la replicación del ADN. La Dra. @AinaMMas, primera autora del trabajo nos cuenta el novedoso descubrimiento. @CIMA_unav @NatureComms

Paper alert ‼️ 🚨 What is the role of RNA in the initiation of DNA replication? We have answers to this long standing question. Yes, RNA has a lot to say in how and where origins are activated. Check out our paper by amazing first author @AinaMMas nature.com/articles/s4146…

Sharing pizza is usually easy. Sharing data can be easy but it's often a bit less so. For my latest story, I chatted with some people all about this: To share is to be a scientist nature.com/articles/s4159…

¡Comenzamos el Genomics Day!!! Una jornada para celebrar el 70 aniversario del #descubrimiento de la doble hélice 🧬 y 20anivesario de la finalización del #ProyectoGenomaHumano. Más de 70 #investigadores reunidos para aprender las bases y nuevas aplicaciones de la #genómica

La expresión de unos ARN largos no codificantes (lncRNAs) predice la supervivencia y prognosis de los pacientes de leucemia mieloide aguda pediátrica. Os lo explica la Dra. @AinaMMas del @CIMA_unav. dciencia.es/arns-largos-no… Adaptado de ascopubs.org/doi/abs/10.120… @ASCO

Understanding the pathway: Long Noncoding #RNA Signatures as Cancer Biomarkers @MaiteHuarteLab @JCO_ASCO @CIMA_unav ascopubs.org/doi/10.1200/JC…

📢📢A novel role for microRNA in controlling sex determination!! Check out our new pre-print! biorxiv.org/content/10.110…