AlbertW_lab

@OlivierDuss @ScienceMagazine @GorKavan Congratulations Olivier!

My first PhD student‘s paper on 5-color single-molecule imaging of co-transcriptional RNA folding is out in @ScienceMagazine Advances! @GorKavan finds that #RNA modification enzymes, antisense oligos and ribosomal proteins re-route nascent RNA folding. See EMBL post below!

We were supported by @IGBMC, @Inserm, @CNRS @unistra, @ERC_research, and @instructhub. 7/7

Big thanks for lots of #TitanKrios time and help to Alexandre Durand @DurandA17996106, Nils Marechal @marechal_nils, @BioS_ME_Alsace, @IGBMC, Michael Hons, Gregory Effantin, and Eaazhisai Kandiah at beamline CM01 @esrfsynchrotron, and @FrommSimon @EmblImaging. 6/7

We study the cooperation between Molecular Machines. Work by Vita Vidmar and @borde_celine in collaboration with @OlivierEspeli and @valeroche looking at the interplay of #Transcription and DNA topology is out: nature.com/articles/s4159… 1/7

Max Planck President Patrick Cramer @mpgpresident has written an open letter to the President of @Harvard, expressing his full support to the University & its stance against demands from the Trump administration to change its policies in order to retain federal funding @maxplanckpress

We are pleased to share our work on the evolution of translation initiation now published in Nature Communications. Take a look at leaderless mRNAs and eS26 in the small ribosomal subunit of Saccharolobus solfataricus. rdcu.be/d5pgg

Please spread the word: we are looking for PhD students! Interested in supramolecular complexes in gene expression? Go to imcbio-phdprogram.unistra.fr scroll down to “Integrated Structural Biology (LabEx INRT)” for project descriptions and start application process by January 19th!

Ever wondered how transcription choreographs histone modifications? Our work reveals the basis of co-transcriptional H3K36me3 by SETD2. We visualize how a histone writer coordinates with the transcription machinery! This is the magnus opus of @MarkertJon tinyurl.com/setd2

@LucasFarnung @MarkertJon Beautiful work - congratulations Lucas and team!

First paper of our lab today @Nature by Nussi! We provide a real-time movie on how #transcription and #translation cooperate using multi-color #single-molecule FM: we find long-range #ribosome-#polymerase communication mediated by #RNA looping! @embl doi.org/10.1038/s41586…

We want to thank additional people involved: Kristine Charles, Nataliya Miropolskaya, Maria Takacs, Charlotte Saint-André, Alexandre Durand @DurandA17996106, Nils Marechal @marechal_nils, @BioS_ME_Alsace, Gregory Effantin, and Eaazhisai Kandiah at beamline CM01 @esrfsynchrotron

Closely related work has also been done in the laboratory of Shun-ichi Sekine: biorxiv.org/content/10.110… 7/7

We are excited to share our latest work on the cooperation between RNA polymerase and the ribosome in bacteria: science.org/doi/10.1126/sc… The work was supported by @IGBMC, @Inserm, @CNRS, @unistra, @ERC_research, @IMC_Bio, and @instructhub. 1/7