Axel Foly

Nice to see this finally out in @NAR_Open ! My final paper from CD lab🥳🥳 Check out how DNA supercoiling influences partition complex formation by ParB! 👇

Out today in @NAR_Open from @cees_dekker lab!! *DNA supercoiling enhances DNA condensation by ParB proteins* doi.org/10.1093/nar/gk… Together with @Aless322 (and @Gruber_Lausanne ) we show the interaction between partition complex proteins (ParB) and supercoiled DNA!

Actual comments of reviewers for the revision of our current paper: Rev #1: “The Methods section is very detailed, ensuring that these experiments can be replicated by others. In fact, it may be too detailed.” Rev #2: “The description of the methods is not detailed enough to enable other scientists to reproduce the experiment” 😵‍💫😵‍💫😵‍💫

A new ‘twist’ on the ParB story out of @cees_dekker lab… 🪢 led by Alejandro Martin Gonzalez (@Aless322) and me we questioned: How do ParB proteins interact with supercoiled DNA? t.co/sUu9VjqtoP 1/11

Had a great time celebrating Sinterklaas with our CD Lab, with a mini @cees_dekker and getting @BiophysLira to scoop a present out of the back of a dog!

@TismaMilos Don't show this to the security officer as they might use it as an idea XD

ChatGPT: A scientist in the lab 👨‍🔬 “Make it messier” (gotta love this trend)🤭

🏆 WIN a Limited Edition Subaru Impreza WRX (number 555 of 555)! All you have to do to enter is 1) Follow @Scalextric 2) Retweet See reply tweet for more info 👇

✨ Meeting our awesome volunteers that are organising this years Pint of Science events all over NL 🇳🇱 Getting ready to bring science back to bars 22-24 May 🍻

@TismaMilos Are there no date-shaped chromosomes?

Donuts or croissants ? 🍩🥐

Have you ever wondered how chromosomes actually look like in bacteria? Our new paper shows the real-time imaging of Bacillus subtilis chromosomes in bacteria! Fresh outta @cees_dekker lab. biorxiv.org/content/10.110… 1/6

Siempre que me piden recomendaciones para ver el atardecer madrileño pongo el Templo de Debod como primera opción por razones más que obvias. 📷mademoisellevit

Now online in @NaturePhysics: our #CDlab paper on a nanoscale rotary machine that we built, a simple DNA bundle that self-organizes into a rotor that autonomously rotates at 10 Hz, as driven by a flow through a nanopore. 🤩 See nature.com/articles/s4156…

Inspired by Dutch windmills, #tudelft researchers created flow-driven rotors from DNA. “These motors are important in biological cells, but the synthetic construction at nanoscale has, until now, remained elusive”, says first author Xin Shi. 🧬 tudelft.nl/en/2022/tu-del… 1/2

Latest #CDlab online in @NatureSMB: nature.com/articles/s4159… SMC proteins can extrude loops of DNA. DNA is often supercoiled. But how do these effects interplay? Using single-molecule visualization, 1st author @eugene_kim__ resolved how these 2 effects work together. 1/3

Great teamwork done by @cees_dekker and #AlejandroGonzalez, @BisLightyear, #JacovanderTorre! It was such a fun time to work in #CDlab as a postdoc (3/3).

Our programme is out! 😍 We will post the specific events details in leading up to dates so don't miss our live events next month #scicomm #wetencomm #pint22 #pintNL

📣Lunes 13-Dic, a las 17.30: CVs PhD-Postdoc day 👏🍏 (online) ¿Te gustaría escuchar sobre la experiencia de nuestros ponentes en su trabajo como phD/postdoc en Países Bajos? 🤔 Tanto si estás en esa etapa como si ya la has pasado, podrás poner ideas y consejos en común🍏🧑🏽‍🔬

Students are preparing the whiteboard in our CDlab corner for Christmas wishes

Y próximamente también... CVs PhD-Postdoc day (ONLINE) 🧑🏽‍🔬 ¡III edición!🍏 🗓️Lunes 13 DIC, 17.30h 💡Evento Ciencias y Vivencias orientado a la aventura pre y post-doctoral 📣Nuestros ponentes phDs y Postdocs nos hablarán de su trabajo y sus experiencias en PPBB ¡Será divertido!

I’m excited to share our new work on the mechanism of ParB spreading in presence of DNA-bound roadblocks, in collaboration with @Gruber_Lausanne and @Dmichiel1 labs where we uncovered an intriguing behavior of this (yet again!😍) spectacular protein… 0/9

Such a nice #CDlab outing yesterday!!