Alex Bateman

Job alert: Biology is amazing (EMD-70204). As a biocurator, you get a front-row seat to the structures being deposited in the world’s structural biology databases. Come join the EMDB and OneDep biocuration team. We’re hiring a biocurator. Apply by 2nd Aug: tinyurl.com/47t93kxp

One of the most-viewed PNAS articles in the last week is “Linear-time prediction of proteome-scale microbial protein interactions.” Explore the article here: ow.ly/MrN950ZhVpi For more trending articles, visit ow.ly/TVz850ZhVpk.

There’s still time to apply! Come and join us as our UniProt Protein Function Development Team Leader, based at @EMBL-EBI in Cambridge, UK. Apply here: embl.wd103.myworkdayjobs.com/EMBL/job/Hinxt… Applications close on 15th July 2026.

Major changes to UniProt proteomes are here! New reference proteome selection workflow, new pan proteome workflow and downloads, and signification increases in the number of species and reference proteomes available. See our release notes: uniprot.org/release-notes/…

@BioinfoAdv Beware of short proteins with pLDDT>70!

🔍 Recently published in Bioinformatics Advances: "Folding the unfoldable 2: Using AlphaFold and ESMFold to explore spurious proteins"  Find the full paper at: doi.org/10.1093/bioadv… Authors include: @Alexbateman1

@Alexbateman1 This study evaluated whether ESMFold and AlphaFold3 assign high confidence scores to spurious protein sequences, as previously observed with AlphaFold2.

@Alexbateman1 💻 Structure predictions and code are available at doi.org/10.5281/zenodo… and github.com/0rra/fold_unfo…

We have finalized major changes to UniProtKB in release 2026_02. Now composed of reference proteome plus additional important proteins and a new collaboration with Google Deepmind. Catch-up on all our changes: uniprot.org/release-notes/…

AI-generated protein annotations are expanding in UniProtKB. The new ProtNLM2 pilot dataset from @GoogleDeepMind covers 26K+ entries, predicting protein name, function, localization, keywords, and GO terms, supported by evidence-based corroboration. uniprot.org/help/ProtNLM

We’re recruiting! Come and join us as our UniProt Protein Function Development Team Leader, based at @emblebi in Cambridge, UK. Apply here: embl.wd103.myworkdayjobs.com/EMBL/job/Hinxt… Applications close on 15th July 2026.

@Alexbateman1 ⚙️ InterProScan 6 documentation is at interproscan6.readthedocs.io. Source code is available at github.com/ebi-pf-team/in….

InterProScan 6 is a complete Nextflow-based reimplementation of InterProScan 5, adding native container support, on-demand data retrieval, and decoupled data management. It delivers roughly 2x runtime speedups on large eukaryotic proteomes while reproducing InterProScan 5 annotations with near-identical precision and sensitivity.

Recently published in Bioinformatics Advances: "InterProScan 6: A modern large-scale protein function annotation pipeline"  Find it here: doi.org/10.1093/bioadv…  Authors include:  @Alexbateman1

Looking forward to speaking about Rfam and RNAcentral at the Cambridge RNA Club!

A new report on EMBL-EBI resources by Frontier Economics shows how tools like UniProt save time, boost productivity and support interdisciplinary collaboration. Read the report highlights: ebi.ac.uk/about/our-impa…

New webinar: Accessing RNA data programmatically with the Rfam and RNAcentral APIs 📅 Thursday 25 June 2026, 14:30–15:30 (BST) 🔗 Registration is free but essential: ebi.ac.uk/training/event… @RNAcentral @RfamDB #bioinformatics

@tatta_bio This is a great opportunity to learn more about SeqHub. It has some super cool features for understanding your genome/protome.

We're offering free 1:1 SeqHub training sessions, tailored to your research. New to the platform or already using it, book a time and we'll walk through what's most relevant to your work. Book here: calendar.app.google/KLFsKvszMMkoSa…

We’ve added more protein structure data to UniProt! We now import data from the 3D-Beacons collaboration of macromolecular structural data providers and for the first time include small angle scattering data. Check CAMK2A to see some of the new data: Q9UQM7 @SIB @EMBLHamburg

There are changes coming to the @uniprot reference proteomes resource. Reference proteomes will remain in UniProtKB, while others will move to UniParc. Read more: ebi.ac.uk/about/news/upd… Uniprot is a collaboration between EMBL-EBI, @ISBSIB & the Protein Information Resource.