Ali Niyaf ⚕ retweetledi
Just because it’s called SMALL vessel disease doesn’t mean it doesn’t have a BIG impact!
Small vessel disease (SVD) is a BIG contributor to vascular dementia, along w/large vessel cortical infarcts
Do YOU know all the faces of small vessel disease?
Common imaging markers of SVD include:
--White matter hyperintensities (WMHs)
--Lacunes
--Enlarged perivascular spaces
--Microbleeds
--Small subcortical infarcts
--Brain atrophy
But what you see isn’t always what you get!
Even in patients w/similar degrees of SVD, clinical symptoms can be very variable.
Variability exists because of:
--Perilesional penumbra
--Remote effects from disruption of brain connectivity
--Differing brain reserve & compensatory mechanisms
So remember, imaging findings of SMALL vessel disease are just the tip of a very BIG iceberg
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