Alon Bar

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Alon Bar

Alon Bar

@AlonBar10

Investigating the endocrine system in health and disease. PhD student at Uri Alon’s lab for systems biology and medicine, Weizmann institute of science.

Israel Katılım Şubat 2020
60 Takip Edilen55 Takipçiler
Alon Bar retweetledi
Meital Oren-Suissa
Meital Oren-Suissa@MeitalOren·
Females are *MUCH* more sexually active than hermaphrodites :) Come hear @EyaWolfson ‘s talk next Monday at #worm23 for more details on the molecular mechanisms and the first description of Caenorhabditis female mating behavior
Eya Wolfson@EyaWolfson

Here's a video we have of this C. afra female being very much intrigued by the extracurricular activity of this other couple. Come see what happens next and how it relates to mating strategies at my talk at #Worm23's Ecology and Evolution session on Monday, 8:30AM @MeitalOren

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Alon Bar
Alon Bar@AlonBar10·
@ShyamSaladi @UriAlonWeizmann @biorxivpreprint Hey Shyam. The numbers suggests 80 datapoints from each pregnancy. This averages to 1 time-point for each test type per pregnancy. In real, some tests types are more common and are done >1 per pregnancy. And some tests types that are not being done in every pregnancy.
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Shyam Saladi
Shyam Saladi@ShyamSaladi·
@UriAlonWeizmann @biorxivpreprint @AlonBar10 awesome dataset and analysis - 45M measurements / .5M pregnancies / 80 test types ≈ 1 time point / pregnancy. is this about right? how often do you have > 1 time point from the same pregnancy? wasn't able to figure this out from the data on GH
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Alon Bar retweetledi
Uri Alon
Uri Alon@UriAlonWeizmann·
1/ 🤰What can we learn about pregnancy form 45 million lab tests? We present a dynamic atlas of pregnancy and postpartum based on measurements from over half a million pregnancies at a one-week resolution. @biorxivpreprint @AlonBar10
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Alon Bar@AlonBar10·
@karlrohe @UriAlonWeizmann Hey Karl, see my comment to this question.
Alon Bar@AlonBar10

@itamar_lev @UriAlonWeizmann Hey Itamar, great question! We choose to plot PC1 and PC3 due to graphical reasons. But the hysteresis does appears in PC1 and PC2. TSNE analysis suggests two clusters - gestation and postpartum. Here is a figure form the SI of the paper that might be interesting for you 😄

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Alon Bar
Alon Bar@AlonBar10·
@AppliedMicrobi2 @UriAlonWeizmann @biorxivpreprint We couldn’t control for testing bias directly. We developed an ascertaining bias score in order to asses this question and removed 31 out of the original 109 different lab tests from our analysis. You can read more about this process in the preprint 😄
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Alon Bar
Alon Bar@AlonBar10·
@LeaskMegan @UriAlonWeizmann @minouye271 @biorxivpreprint We did, but we weren’t confident that the data is reliable enough in order to be included in our analysis. This is mainly because prolactin is not done regularly. Our prolactin data might not represent healthy pregnancy. Prolactin data is shown in the supplement section.
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Alon Bar
Alon Bar@AlonBar10·
@itamar_lev @UriAlonWeizmann Hey Itamar, great question! We choose to plot PC1 and PC3 due to graphical reasons. But the hysteresis does appears in PC1 and PC2. TSNE analysis suggests two clusters - gestation and postpartum. Here is a figure form the SI of the paper that might be interesting for you 😄
Alon Bar tweet media
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Itamar Lev
Itamar Lev@itamar_lev·
@UriAlonWeizmann Uri maybe it appears in the paper, I am curious why do you plot Pc1 and Pc3 skipping Pc2?
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Alon Bar retweetledi
Uri Alon
Uri Alon@UriAlonWeizmann·
Damage dynamics in individual E. coli cells as they age explains why identical cells die at different times. Amazingly, damage follows a stochastic equation found also in mice. Aging may be universal in its fundamental dynamics. #qbio #aging disq.us/t/4ftdprd
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Alon Bar retweetledi
Tomer Milo
Tomer Milo@MiloTomer·
Is it possible that Graves' and Hashimoto's, two opposite autoimmune diseases of the thyroid, have the same origin? We suggest they do and that their origin even has an important physiological role for all of us cell.com/trends/immunol… @TrendsImmuno
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Alon Bar retweetledi
Lada
Lada@LadaPechuk·
I can't believe it's out there, the preprint of my first project! Thanks to everyone who helped me in this journey. Now what? BTW, the last two figures are my personal favorites :)
Meital Oren-Suissa@MeitalOren

Can sex-specific synapses essential for behavior be predicted and reprogrammed? Yes they can! 🔥new preprint from our lab🔥 Fun collaboration with @EladSchneidman, work by the talented @LadaPechuk, @gal_goldman and Yehuda Salzberg biorxiv.org/content/10.110…

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Alon Bar retweetledi
Uri Alon
Uri Alon@UriAlonWeizmann·
My new course Hormone Circuits is now on YouTube. Each of the 11 lectures has a special guitar song. Lecture 1 is about the weight set-point. youtube.com/watch?v=X2n7QR…
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Alon Bar
Alon Bar@AlonBar10·
@HiggsBozoEffect ״הסוד״. קרה לי באמת בדייט, לא קמתי והלכתי מתוך נימוס, אבל ללא ספק זה היה הרגע המכריע שקבע שלא יהיה דייט שני
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Higgs Bozo
Higgs Bozo@HiggsBozoEffect·
אתם בדייט ראשון, הדייט מגלה לכם את השם של הספר האהוב עליה/ו. בתגובה, אתם קמים והולכים מיד. איזה ספר זה?
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Keşfet

@EyaWolfson @ShyamSaladi @UriAlonWeizmann @biorxivpreprint @karlrohe @AppliedMicrobi2 @LeaskMegan @itamar_lev