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I am transitioning from dark to blue skies 🦋 and I will shortly close this account. I hope to see you in the other side 🙌
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Alvaro Köhn-Luque
2K posts
Alvaro Köhn-Luque
@AlvaroKohn
Senior scientist @OCBE_UniOslo, mathematician working on personalized cancer medicine using mechanistic modeling, machine leaning or combinations of both.
Oslo, Noruega Katılım Şubat 2016
2.3K Takip Edilen1.3K Takipçiler
Don’t miss this great summary of our latest preprint
Youness@YounessAzimzade
If you are interested in immune cells in tumors and their impact on clinical outcomes, our latest work might interest you: biorxiv.org/content/10.110…. We pose a simple question: how is the abundance of different cell types associated with treatment response and relapse? 1/n
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Leah Edelstein-Keshet (University of British Columbia), Modeling & simulating single cell motility optogenetic experiments birs.ca/events/2024/5-…
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Congratulations to @MyelomaOslo on your public disclosure, “Relapse prediction in multiple myeloma patients treated with isatuximab, carfilzomib, and dexamethasone.” We’re proud to facilitate your access to data #ClinicalResearch doi.org/10.1101/2024.0…
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Mads Haugen presenting at Lewis-Sigler institute work from his group and RESCUER
@YounessAzimzade @AlvaroKohn @freeges
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Excellent review from @mariangelaruss2 @BardelliLab discussing our current understanding of drug-tolerant persister cells in cancer.
nature.com/articles/s4156…
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'Mechanisms that clear mutations drive field cancerization in mammary tissue'
nature.com/articles/s4158…
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@mtmdphd @VincentRK @TheLancetOncol Sure, but what you think is the effect of low dose on the cancer compared to high dose?
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@AlvaroKohn @VincentRK @TheLancetOncol high dose dex has side effects including increased infections.
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Lenalidomide + high-dose dexamethasone (RD) vs lenalidomide + low-dose dexamethasone (Rd) as initial therapy for newly diagnosed multiple myeloma: an open-label RCT [10/22/2009] @VincentRK et al. @TheLancetOncol ow.ly/K86r50BK0Gj #NCT00098475 #EAonc E4A03 #mmsm #caxtx #ctsm
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@mtmdphd @VincentRK @TheLancetOncol Is any mechanism mentioned in the paper? Toxicity? That would be important but not so interesting as I thought it could be…
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Just on time for labor day weekend (for those of you State-side)
@mathoncbro writes about mechanistic learning, the best of two worlds based on a paper by @jmetzcar @MathCancer @AlvaroKohn @Jutzeler_Cathy and Sara Bruningk:
mathematical-oncology.org/blog/mechanist…
#MachineLearning #MathOnco
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Excited to share the fruits of a new collaboration with @AguadeGuim and @ricard_sole on: Modeling tumors as complex ecosystems. This perspective is open access with almost 230 references - out now in @iScience_CP cell.com/iscience/fullt…
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Oxford Mathematician and Fellow of @StJohnsOx Philip Maini has been awarded the Sylvester Medal by the @royalsociety for his contributions to mathematical biology.
Pretty good teacher too.
maths.ox.ac.uk/node/68841
Photo: Robert Taylor/St John's
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Don’t miss these remarks of our review paper by the amazing @mathoncbro 🙌 thank you 🙏 @OCBE_UniOslo #mathonco
Jeffrey West@mathoncbro
This paper has my vote for Most Interesting & Provocative new ideas in "philosophy of modeling" in the last several years: frontiersin.org/journals/immun… My summary: 🧵🧵🧵
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30 Essays to Make You Love Biology
Day 1. "I should have loved biology" by James Somers.
"It was only in college, when I read Douglas Hofstadter’s Gödel, Escher, Bach, that I came to understand cells as recursively self-modifying programs."
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Great first day at #ECMTB24 including interesting talks on integrating mechanistic models and machine learning in mathematical oncology by @guillelorenzogz and @SBruningk.
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Attended to the first session „mechanistic learning in mathematical oncology“ organised by @AlvaroKohn.
Babis @M3sBiomath gave his talk on making clinical predictions without understanding everything.
@ecmtb2024 #Toledo #math_onco
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Dear ECMTB2024 participants,
The 13th Edition of the European Conference on Mathematical and Theoretical Biology ecmtb2024.org is just around the corner so, before arriving in Toledo, we would like to give you some indications.
🧵(1/10)
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Read the article: Computational model predicts patient outcomes in Luminal B breast cancer treated with endocrine therapy and CDK4/6 inhibition.
bit.ly/3Y9UEXR
Alvaro Köhn-Luque@AlvaroKohn
Thanks for highlighting our recent @CCR_AACR paper predicting patient outcomes in breast cancer treated with endocrine therapy and CDK4/6 inhibition. Also really looking forward to read the ctDNA paper of #JasmineFoo et al. And congratulations on the 300 #MathOnco edition!
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Thanks for highlighting our recent @CCR_AACR paper predicting patient outcomes in breast cancer treated with endocrine therapy and CDK4/6 inhibition. Also really looking forward to read the ctDNA paper of #JasmineFoo et al. And congratulations on the 300 #MathOnco edition!
Jeffrey West@mathoncbro
This week in #MathOnco 300! ecological interactions, predictive modeling, CT DNA kinetics, and more... Art: Artist: Mark Chaplain (@mcapellanus), Nikos Sfakianakis, Dimitris Katsaounis, Nicholas Harbour, Thomas Williams Signup: mathematical-oncology.org/newsletter
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