Andrew Baird

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Andrew Baird

Andrew Baird

@AndrewDBaird1

Writer, Hair loss researcher, Healthy eating coach, Vitamin A toxicity experimenter, astrologer, film watcher & soundtrack listener, Food waste economics.

Dundee, Scotland Katılım Nisan 2011
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Andrew Baird
Andrew Baird@AndrewDBaird1·
How do you go about this Vitamin A reduction ? 1. Take out the multivitamins (virtually always high beta carotene and/or high Vitamin A) and high single supplements of Vitamin A. Take out cod liver oil. Take out daily liver consumption of 50 grams or more. 2. Continue eating eggs or 1-3 brazil nuts for selenium. 3. Do Epsom salt baths for magnesium (potassium tends to be low also if magnesium is low) and sulphur bypassing intestine. 4. Eat some beans like black beans, nuts like macadamia nuts or sunflower seeds for copper and B1. 5. Eat some black eye peas/cow peas or other beans for molybdenum. 6. Eat some beef or oysters (high in copper might not work for everyone) for zinc. 7. Consider the gut issue: oxalates, FODMAPS, histamine intolerance, glutamate, salicylates, polyphenols, nitrates, carotenoids (high ethanol problem) and adjust balance away from highest foods. 8. Address metabolic acidosis with breathing techniques and bicarbonate (careful not to deplete stomach acid too much or deplete copper). B12 might be helpful for high nitric oxide. 9. Then increase betaine foods like organic spelt or einkorn, quinoa or beetroot. 10. Then increase choline foods like beef or eggs. 11. Increase B5 foods like chicken, avocado, eggs and mushrooms (might be gut issues re FODMAPs or glutamate issues). 12. Increase B1 foods like sunflower seeds, pork (if not against religious beliefs), oats and macadamia nuts. 13. Consume some extra virgin olive oil for Vitamin E and Coenzyme Q10. Mackerel another source of Coenzyme Q10. 14. Consume some food sources of Vitamin C like kiwis, cauliflower and strawberries. 15. Supplement with low amounts where necessary. May need to be higher at first. With improving absorption from eggs in particular doses may need reduced. 16. Find alternative foods where not tolerated or contradicted by gut issues. 17. For some people this will not be easy and you need professional help. 18. For some people very little healing will take place until the stress in their life is reduced. Improving sleep can help the equation particularly going to bed early in winter. Yoga, breathing and brain wave music. Other techniques. Physical and mental postural therapies. 19. Some form of light exercise or walking may help. Lifting small amounts may also help gut health. Lymph work may also help. 20. Go low and slow at first with new interventions, foods and supplements.
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Andrew Baird
Andrew Baird@AndrewDBaird1·
A high meat and therefore a high phosphorus diet and very low calcium is going to lead to problems with high phosphate absorption too.
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Andrew Baird
Andrew Baird@AndrewDBaird1·
Why is gut dysbiosis getting worse on a very low vitamin A diet ? I ate one egg a day, had some variety in my diet and I still got slightly worse I reckon. I was low calcium and perhaps too moderate for fat intake in last few years attempting to improve bile flow. I also might have needed some more zinc although it never really helped until I addressed the leaky gut problem.
Andrew Baird@AndrewDBaird1

Here's the prime suspects for why the gut dysbiosis got worse in order of importance in my opinion. 1. Too low Vitamin A (one egg a day and 75 mcgs RAE isnt quite enough). 2. Lack of variety for different food fibres. 3. Lack of moderate carotenoids like beta carotene AND lutein and lycopene. 4. Low calcium. 5. Endotoxemia from the start. Malabsorption. 6. Fear mongering over foods. Unhelpful atmosphere for some. 7. Leaky gut increased need for choline and betaine. 8. Leaky gut leading to poor B1 absorption exacerbating a number of issues. 9. Lack of Vitamin K in foods. Fat malabsorption. 10. Low in Vitamin C and Vitamin E foods.

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Andrew Baird
Andrew Baird@AndrewDBaird1·
He also said many in the 'community' had sulfite problems. Converting sulfur to sulfate is one of the keys to detoxing better. And it's not simply molybdenum. Avoiding other sulfur foods for years and years not really helping much when you could have solved the sulfur metabolism problem. Sulfur amino acids being high in meat ironically.
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Dr. Vadgers
Dr. Vadgers@MeSo_Hungy·
@DrSteveGoeddeke his theory is just so disjointed. Secondary bile acids are necessary but high levels are damaging. What causes these high levels? Dysbiosis. Same with high TMAO. Not to mention that sulfur is bad because it is associated with the devil.
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Steve Goeddeke
Steve Goeddeke@DrSteveGoeddeke·
In hindsight, it's pretty obvious there were big things missing in the model. The model predicted easy slam dunks but there were too many people struggling after years.
Dr. Vadgers@MeSo_Hungy

@AndrewDBaird1 I also spent 5 years battling through the endless symptoms that just got worse over time. The forums bear this out over and over. The stupid toxic bile/ 0 vitamin A causes ones to double down and think they are detoxing hard. If vitamin A helps, it must be bad - "stop detox".

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Andrew Baird
Andrew Baird@AndrewDBaird1·
I agree. I think also those with fatty liver might also look to improve intestinal barrier function as the leaky gut and elevated lipopolysaccharides (LPS) might be reducing absorption of choline and B1. I was eating 3-4 eggs a day and plenty of meat to try to outrun a sulfite toxicity and a leaky gut. Sulfites bind to betaine aldehyde so you lose choline converting to betaine at this point too. Increasing the need for choline because the leaky gut hasnt been resolved. LPS increasing fatty liver and needing choline being a vicious cycle too.
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Elijah Krings
Elijah Krings@Elijahkrings·
Choline is such a miracle molecule, I would still consider it being a vitamin Its probably the most protective compound for your liver, while also having the possibility to heal harsh liver conditions Low levels of choline are found in most pancreatic cancer patients and higher levels are associated with lower risk of development Choline is highly important in membrane make up, as a huge share of phospholipids need choline as their polar head group High amounts of nutrients & ATP are used up through methylation to produce choline, so low intake will naturally zap you of B1/B2/B3/6/9/12, ATP, Glycine, Methionine and might increase homocysteine, which in itself is a risk factor for CVDs Choline is needed for bile synthesis and export of toxins from the liver into the bile duct. After all, its a supportive intervention for detoxifying all sorts of toxins If you are not eating >4 eggs per day, you will lack it in this modern world. Possibly 6 eggs per day, liver 1-2x per week and even then some cases might benefit from supplemental form through genetic snippets & disease history
Elijah Krings tweet media
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Andrew Baird
Andrew Baird@AndrewDBaird1·
Here's the prime suspects for why the gut dysbiosis got worse in order of importance in my opinion. 1. Too low Vitamin A (one egg a day and 75 mcgs RAE isnt quite enough). 2. Lack of variety for different food fibres. 3. Lack of moderate carotenoids like beta carotene AND lutein and lycopene. 4. Low calcium. 5. Endotoxemia from the start. Malabsorption. 6. Fear mongering over foods. Unhelpful atmosphere for some. 7. Leaky gut increased need for choline and betaine. 8. Leaky gut leading to poor B1 absorption exacerbating a number of issues. 9. Lack of Vitamin K in foods. Fat malabsorption. 10. Low in Vitamin C and Vitamin E foods.
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Steve Goeddeke
Steve Goeddeke@DrSteveGoeddeke·
This seems to be true for me. I did 3 years on the diet, and while some major things improved early on, over time I did get worse in new and different ways, very slowly, so it was confusing. Toxic bile "theory" was a beautiful theory, but IME testing it over a long time period, the rubber didn't meet the road, so I think the model is flawed. Shame, because I love myself a good model that seems internally consistent. Basically my gut dysbiosis was able to slowly worsen even eating super clean, lowering potential toxin intake to near zero. Not sure why exactly yet. That would be good to know.
Dr. Vadgers@MeSo_Hungy

@AndrewDBaird1 I had a little chat with Garrett and his angle is that we fix the gut/endotoxemia by first fixing the liver. I believe it is the other way around. Your basement is flooded with waste and he's trying to fix the sump pump instead of stop the flooding first.

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Andrew Baird
Andrew Baird@AndrewDBaird1·
People arent eating enough meat and eggs. Avoiding egg yolks. Low intake of folate and B12. Leaky gut might be a problem too. Sulfite toxicity also loses choline at the betaine aldehyde point in conversion to betaine. Then there's the factors worsening fatty liver and increasing need for choline. Pregnant women have increased demand for choline too.
Dr Sam Soete@sam_soete

Choline deficiency is hidden pandemic "Analyses of NHANES data indicate that only about 10–11% of US adults meet the IOM Adequate Intake (AI) for choline."

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Andrew Baird
Andrew Baird@AndrewDBaird1·
People arent eating enough meat and eggs. Avoiding egg yolks. Low intake of folate and B12. Leaky gut might be a problem too. Sulfite toxicity also loses choline at the betaine aldehyde point in conversion to betaine. Then there's the factors worsening fatty liver and increasing need for choline. Pregnant women have increased demand for choline too.
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Dr Sam Soete
Dr Sam Soete@sam_soete·
Choline deficiency is hidden pandemic "Analyses of NHANES data indicate that only about 10–11% of US adults meet the IOM Adequate Intake (AI) for choline."
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Andrew Baird
Andrew Baird@AndrewDBaird1·
She could have Vitamin A toxicity and/or a deficiency of retinoic acid. Estrogen improves the conversion of retinol to retinoic acid. Beneficial for brain fog and skin. Not always such good results for HRT helping dry eyes though. HRT users tended to have higher prevalence of dry eye syndrome compared to non-users.
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Mike Roberto
Mike Roberto@MicroBerto·
Did @megynkelly have vitamin A toxicity, and did hormone replacement therapy somehow combat its symptoms? And if so, how would this work? Symptom masking, or true metabolic enhancement to help detoxify it faster? This is interesting. Dry eyes, brain fog, skin problems are all obvious signs, and health nuts always push vitamin A containing foods and supplements too hard, so it definitely fits.
Camus@newstart_2024

Megyn Kelly just got brutally honest about HRT: “I’m on it and I love it.” She says it completely fixed her dry eye, cleared brain fog, improved her skin, and made her feel vibrant again — things she had no idea were hormone-related. Her attitude? “I’m going down swinging.” No shame in doing what actually works as you get older. Josh Duhamel backed her up, saying she’s the perfect poster child for it and the science is there. It’s one of the most refreshing takes I’ve heard on a topic people usually tiptoe around. Have you (or someone you know) tried HRT and seen real changes?

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Andrew Baird
Andrew Baird@AndrewDBaird1·
Some people need to take the polyphenols slowly. High polyphenols tend to be high salicylate and there's probably more salicylate sensitivity problems in those who went very low vitamin A. You might react to the highest ones like berries, green tea, turmeric, oregano, red grapes, broccoli, peppers, apples with skin, pomegranate and tree nuts. Symptoms include sneezing, runny nose, wheezing, skin flare-ups, digestive problems and headaches. Lower salicylates for a month or two and sensitivity hopefully declines. Which foods are low salicylate and good for polyphenols ? Red onions, peeled ripe pear, mango, banana, peeled white potato, cabbage, iceberg lettuce, celery, cashews, peanuts, extra virgin olive oil and dark chocolate.
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Andrew Baird
Andrew Baird@AndrewDBaird1·
Say you believed toxic bile theory and very low vitamin A was going to resolve leaky gut. How long would you continue with your programme and still think it was working ? 5 years for example is a long time to continue with leaky gut and related problems like skin problems, insulin resistance, gut motility, gall bladder contraction issues and cognitive issues. Many cases of leaky gut could be resolved in 6-24 months with a moderate improvement in toxic bile. It depends how significant your bile acid issues are. In my opinion it would be much quicker to resolve leaky gut and reduce symptoms. I mean what are you doing differently in trying to fix leaky gut rather than toxic bile ? You're doing zinc, magnesium, potassium, more fibre, lower fat, niacin in any case. What's the difference in the two approaches ? Basically I'm saying improve absorption and your supplement bill might reduce. Choline and B1 which help toxic bile theory in any case would improve with better absorption. Gallbladder emptying, digestive motility and bile flow would improve with better absorbed B1 and choline. Three daily portions of foods with polyphenols significantly helped leaky gut in one 8 week trial. Foods like berries, blood orange/pomegranate juice, green tea, Renetta apple and dark chocolate/cocoa. All these polyphenol foods incidentally help toxic bile too. So what are we left with ? Well assuming you correct the errors of low choline, low betaine and low polyphenols the only thing you have left is very low vitamin A is sabotaging the leaky gut healing. And strangely enough it may be worsening bile acid dysregulation, cholestasis and related liver/gut stress which can indirectly promote a more toxic bile acid profile or make the gut more vulnerable to bile-induced damage. You're not healing leaky gut or toxic bile with a very low vitamin A approach. In fact a small amount of carotenoids and retinol may actually resolve both. Resolve the leaky gut and you dont need so much choline because it's better absorbed. Leaky gut causing fatty liver disease ironically is alleviated too and hopefully choline to betaine and choline to phosphatidylcholine conversions improve too. Less drain on methylation resources. You've still got creatine needing a lot of methylation resources but fixing leaky gut supports methylation through better absorption of B12 and folate, reduced inflammation, healthier microbiome and lower homocysteine burden. Methylation is needed for detox. All those LPS symptoms and you thinking it was detox. You need some Vitamin A and going near zero never improved the detox of it much at all.
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Andrew Baird
Andrew Baird@AndrewDBaird1·
If healing is slow for the big issues you have then consider leaky gut is reducing absorption of B1. It's a vicious cycle too as low B1 may slow the healing of the gut barrier. You might need to emphasis B1 foods like pork, sunflower seeds, oats, beans and macadamia nuts or supplement 10-20 mgs. Gut motility, gallbladder clearing and digestion might all be poor and toxic bile theory isnt going to fix leaky gut to help you. Anxiety and poor parasympathetic activity will keep you stuck in poor gut motility and poor lymph function. No matter what you do with improving sleep and nervous calming techniques healing is going to be very slow. Work on leaky gut first with zinc, polyphenols, some choline, some betaine, low fat, some lutein, some lycopene and at least 100 mcgs RAE of Vitamin A sources.
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Andrew Baird
Andrew Baird@AndrewDBaird1·
It's so obvious now that I've had an endotoxemia issue for a long time. Start sneezing for some indeterminate reason like an artificial perfume or overdoing salicylates and I take a zinc supplement and sneezing and runny nose disappear. Further back before I started eating more eggs I got weird upper body cramps and took a zinc supplement and they disappeared right away. Too low vitamin A and low polyphenols will make this worse. Fix the endotoxemia and stop obsessing about tiny amounts of Vitamin A.
Andrew Baird@AndrewDBaird1

Thought for the day. If you're constantly taking zinc then are you simply trying to improve intestinal barrier integrity to stop all those substances 'leaking' out and causing immune reactions ? LPS, undigested proteins, lectins and histamine for example. Zinc will also help the first part of retinol to retinoic acid conversion helping the barrier that way too. It's why zinc and Vitamin A in moderation helps skin. With better integrity better absorption of nutrients would tend to occur too. I can take zinc and very quickly reactions stop like previously weird cramps or sneezing. You need to get at the root cause or you will have a high supplement bill. If zinc supplementing cant be stopped without issues then consider whether your Vitamin A is too low. Below 100 mcgs RAE is counter productive I'd suggest. Choline through phosphatidylcholine supports intestinal barrier integrity too. Initially fat in eggs might make LPS worse and toxins being released also might give the appearance of reactions but gradually they often help. Reducing histamine liberators, improving good bacteria with resistant starch, reducing high consumption of wheat, meat, beans or dairy and increasing polyphenols will all address root causes. There shouldn't be a continual demand for supplemented zinc for those eating over 200 grams of meat per day and getting over 8-11 mgs per day. You need small amounts of copper too and no dietary copper and high zinc intake (above 25 mgs) isnt going to help copper functions like iron regulation and antioxidant support either. It's likely you are plugging holes in your gut whilst creating a hole in your pocket with supplement bills.

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Andrew Baird
Andrew Baird@AndrewDBaird1·
yes, even in some of the previously highest vitamin A supplementers there was none of these supposed detox symptoms because they kept some Vitamin A in the diet. No skin problems. And you are so right we should have realised Vitamin A stopping the 'detox' was us helping the intestinal barrier. Finally some moments of clarity. Thanks.
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Dr. Vadgers
Dr. Vadgers@MeSo_Hungy·
@AndrewDBaird1 I also spent 5 years battling through the endless symptoms that just got worse over time. The forums bear this out over and over. The stupid toxic bile/ 0 vitamin A causes ones to double down and think they are detoxing hard. If vitamin A helps, it must be bad - "stop detox".
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Andrew Baird
Andrew Baird@AndrewDBaird1·
It depends what exactly the problem is. Overdoing meat and/or overdoing fibre could cause different problems. My general approach would be to encourage the good bacteria and improved intestinal barrier integrity. Improve sleep and reduce stress if these are factors. Eating 2-3 eggs a day if tolerated plus a betaine food source to help the liver. Moderate protein. More answers here: x.com/AndrewDBaird1/…
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Andrew Baird
Andrew Baird@AndrewDBaird1·
You could be increasing zinc, increasing fibre and lowering fat for your endotoxemia and intestinal barrier integrity and doing worse because the low Vitamin A is unable to counter LPS damage. Tight junctions and epithelial integrity can remain compromised leading to more LPS leakage, worse endotoxemia and related symptoms. The inflammation, fatigue and autonomic issues being LPS and not detox being tough. pubmed.ncbi.nlm.nih.gov/30747184/
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Andrew Baird
Andrew Baird@AndrewDBaird1·
@DrSteveGoeddeke yes, I've been following and it's very interesting. I think it might be your B1 is improving amongst other things. B1 foods now being better absorbed. You could also do a lying to standing blood pressure test too although you might be well recovered already.
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Steve Goeddeke
Steve Goeddeke@DrSteveGoeddeke·
@AndrewDBaird1 Going after bacterial overgrowth (endotoxins) the last 3 months is improving my ANS problems
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Andrew Baird
Andrew Baird@AndrewDBaird1·
It's also worth noting that endotoxemia may reduce absorption of choline too so your toxic bile acids will have less protection and bile flow might be slower.
Andrew Baird@AndrewDBaird1

Phosphatidylcholine is one of the key protective factors against toxic bile acids. While the two are interconnected endotoxemia is actually a bigger factor in overall human illness than toxic bile. Elevated LPS having far broader and more extensively documented links to common chronic diseases. If you're worsening endotoxemia whilst focusing on toxic bile theory without considering phosphatidylcholine then you've got really confused somewhere along the way. Low fat, zinc and fibre though being helpful. Very low Vitamin A is one of the worst things you could do for endotoxemia. Low polyphenols compounding the error. Sometimes you need to step back and ask yourself does this all make sense from a macro level ?

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