Angela Johns

209 posts

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Angela Johns

Angela Johns

@AngyJohns

PhD student at @TheVilchezLab @CECAD_ via @CGA_age | #Ageing, #Neurodegeneration, #ALS, and everything beyond and in between | 🇵🇭🇫🇮🇸🇪🇩🇪

Cologne, Germany Katılım Temmuz 2021
375 Takip Edilen129 Takipçiler
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Angela Johns
Angela Johns@AngyJohns·
Check out our new publication on protein quality control, from my masters internship in University of Gothenburg! Thanks for the awesome supervision @ArthurFischbach and Thomas Nyström! Congratulations! 🎉🎉🎉
Arthur Fischbach@ArthurFischbach

Very excited to share my latest work on #aging and #proteostasis published now in @NatureComms. Here, we report on engineered, artificial systems to export endogenous or mutant huntingtin protein aggregates from cells rdcu.be/dbLTH nature.com/articles/s4146…

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Benedict Tan
Benedict Tan@mustloveDNA·
PhD Opportunity - I am recruiting a student to investigate mechanisms of co-transcriptional RNA processing in human mitochondria. This is in collaboration with @hauke_hillen and is funded by the DFG @dfg_public . Deadline 3 January 2025. Apply below⬇️: bit.ly/3Z2VS5M
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David Vilchez
David Vilchez@TheVilchezLab·
New paper from the lab! ALS-FUS mutations cause abnormal PARylation and histone H1.2 interaction, leading to pathological changes: cell.com/cell-reports/f… #ALS
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Universität zu Köln
Universität zu Köln@UniCologne·
🎉 Congratulations to @AleXTrifunovic on her @EMBO membership🎉 👩‍🔬🧬The award recognizes her outstanding research, in particular her pioneering work on the role of mitochondria in aging and disease @CECAD_ 🔬 Read more👇 uni.koeln/2CGBY
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David Vilchez
David Vilchez@TheVilchezLab·
Congrats Dr. Bilican! Great job, excellent thesis defense! @CGA_age
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mitojobs
mitojobs@mitojobs·
Apologies for the link above, here’s one that works bit.ly/4ayZuRx
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mitojobs
mitojobs@mitojobs·
Hello mitoverse ✨ @mustloveDNA is hiring! If you’re looking for a PhD position in Marburg, DE and you’d like to investigate mitochondrial gene expression, apply here stellenangebote.uni-marburg.de/jobposting/c09…. I promise mt gene expression can be fun and Ben is a great mentor. Deadline 05/05/2024
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Benedict Tan
Benedict Tan@mustloveDNA·
PhD opportunity! My new research group at the University of Marburg @Uni_MR is once again recruiting a highly-motivated PhD student to investigate molecular mechanisms of mitochondrial gene expression. Deadline 5/5/2024. Apply now using the link below!⬇️ bit.ly/4ayZuRx
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CECAD Cologne
CECAD Cologne@CECAD_·
✨🚺Happy International #WomensDay ! ✨ Today, on #March8, we honor the diverse voices, experiences, and contributions of women worldwide, as we strive for equality! Here's to all the incredible people who identify as women in our @CECAD_ community and worldwide! #IWD2024
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Benedict Tan
Benedict Tan@mustloveDNA·
PhD opportunity! My new research group at the University of Marburg @Uni_MR is looking for a highly-motivated PhD student to investigate molecular mechanisms of mitochondrial gene expression. Apply now using the link below!⬇️ Deadline is 3 March 2024. bit.ly/3uhLUSI
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Malene Hansen Lab
Malene Hansen Lab@thehansenlab·
Very excited to share our latest work on non-canonical autophagy and aging @NatureAging - thanks to all of the co-authors @Buck, @sbpdiscovery and @RutgersU! Big cudos especially to Assistant Professor Dr. Caroline Kumsta @Kumsta!
Nature Aging@NatureAging

Online now! Yang et al. show that inhibition of early-acting autophagy genes in neurons extend C. elegans lifespan, improve proteostasis, and increase #exopher formation via the autonomous WD40 domain-related function of ATG-16.2. @kumsta @thehansenlab rdcu.be/dvaFk

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Benedict Tan
Benedict Tan@mustloveDNA·
New year, new beginnings - I am pleased to announce that I am starting as a Junior Group Leader at the University of Marburg @Uni_MR investigating molecular mechanisms of mitochondrial gene expression. Looking forward to working with an incredibly vibrant RNA community!
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David Vilchez
David Vilchez@TheVilchezLab·
Very happy to share our preprint that further confirms changes in ubiquitination during aging in C. elegans biorxiv.org/content/10.110…
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David Vilchez
David Vilchez@TheVilchezLab·
Wow! Very happy to see that the extensive change in the protein ubiquitination landscape is a major proteostasis signature during aging which is evolutionary conserved in vertebrates
Alessandro Ori@AOri_lab

6/Our work demonstrates that remodeling of protein ubiquitylation is a major proteostasis signature of aging extending previous findings in nematodes by @TheVilchezLab to the vertebrate brain nature.com/articles/s4158…

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David Vilchez
David Vilchez@TheVilchezLab·
Terrific work from Alessandro's lab (as usual) demonstrating extensive remodeling of the ubiquitination landscape during aging in mice and killifish! The authors also provide mechanistic insights on how a third of these changes occur
Alessandro Ori@AOri_lab

In our latest pre-print, we studied how protein post-translational modifications (PTMs) change during brain aging. Kudos to the incredible team at @AOri_lab @AntonioMarinoMB @DomenicoFraia @panfilovadi @AmitKusahu1598 biorxiv.org/content/10.110…

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David Vilchez
David Vilchez@TheVilchezLab·
Thank you @impetusgrants for your support! @MarkusWehrmann_ had the exciting idea to use his expertise on directed evolution for aging research
Impetus@impetusgrants

Decline in proteostasis and lysosomal function during aging leads to improper protein degradation and accumulation of toxic proteins. @TheVilchezLab @MarkusWehrmann_ are using directed evolution to engineer protein variants that can effectively reduce aggregates during aging.

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Impetus
Impetus@impetusgrants·
Decline in proteostasis and lysosomal function during aging leads to improper protein degradation and accumulation of toxic proteins. @TheVilchezLab @MarkusWehrmann_ are using directed evolution to engineer protein variants that can effectively reduce aggregates during aging.
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Markus Wehrmann
Markus Wehrmann@MarkusWehrmann_·
It feels unreal to receive my first grant this early on in my career by @impetusgrants. Especially grateful to @TheVilchezLab that enabled and supported me to follow my own ideas and projects. x.com/impetusgrants/…
Impetus@impetusgrants

Decline in proteostasis and lysosomal function during aging leads to improper protein degradation and accumulation of toxic proteins. @TheVilchezLab @MarkusWehrmann_ are using directed evolution to engineer protein variants that can effectively reduce aggregates during aging.

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Keşfet

@hauke_hillen @dfg_public @AleXTrifunovic @EMBO @CECAD_ @TheVilchezLab @CGA_age @mustloveDNA