Anxo Martinez-Ordoñez

Online now: Epithelial aPKC deficiency leads to stem cell loss preceding metaplasia in colorectal cancer initiation dlvr.it/T7YnVs

Exciting news! Our latest research in @Dev_Cell explores the link between intestinal metaplasia & CRC initiation! This could help identify new targets for early cancer prevention #CRC #WCM @WCMCPathology x.com/Dev_Cell/statu…

Our findings suggest a potential avenue for serrated chemoprevention by targeting cholesterol biosynthesis. Check out the full study for details! (2/2) #Science #Research #CholesterolBiosynthesis #CancerPrevention 📑 link.springer.com/10.1038/s41467… @WCMCPathology

Just published! Our latest research reveals the crucial role of atypical PKCs (aPKC), PKCλ/ι, in modulating cholesterol biosynthesis through SCAP phosphorylation. This regulatory pathway impacts SREBP2 activation, influencing cell metaplasia in serrated tumors (1/2)

It was also really cool to have the perspective of @Montse_Rojo_PhD on science and high-impact factor journals.

I had the opportunity to attend the Cell and Cancer Pathobiology Symposium at @WCMCPathology last week. Outstanding science and talks!

Fue un placer hablar con @manuelansede y contarle nuestros nuevos resultados… lo explica el mejor que yo! … leelo aquí: elpais.com/ciencia/2023-0…

Congrats to @MReinaCampos on their paper being published in Nature!!!This is a huge accomplishment, and I can't wait to read it. Amazing science!!!

“An image can be very convincing when you are investigating a mechanism. It’s kind of trying to get the answer from the tumor itself,” Dr. Maria T. Diaz-Meco from @WCMCPathology in @DrugDiscovNews. #PathTwitter drugdiscoverynews.com/color-coding-c…

Check out our #protocol published @STARProtocols from Moscat’s lab at @WCMCPathology describing whole mounting staining in #CRC organoids in co-culture with fibroblasts sciencedirect.com/science/articl… Research in @Cancer_Cell

New York is currently experiencing some of the worst air quality in history due to wildfires burning in Canada. Views from the lab

Online Now: Exhaustion-associated cholesterol deficiency dampens the cytotoxic arm of antitumor immunity dlvr.it/Sph47f

Sometimes you come across quiet heroes. Quiet heroes don't necessarily score goals, have a great voice or millions of followers on social. They just do what's necessary to make this world a better place! I’m lucky to call one of these people, friend! Proud of you, @AnxoMatri !

Online Now: Hyaluronan driven by epithelial aPKC deficiency remodels the microenvironment and creates a vulnerability in mesenchymal colorectal cancer dlvr.it/SfQK0n

Please join us in congratulating our colleagues on this important new research!

We are very excited to share our work on mesenchymal CRC driven by aPKC deficiency and Hyaluronan deposition in @Cancer_Cell. A huge thank you to everyone who supported and contributed to this amazing project!!! @WCMCPathology authors.elsevier.com/a/1gFo25TA51Zn…

Scientists uncover mechanisms that tumors use to force nearby cells to aid their growth, according to a new study from @WCMCPathology and @WCM_MeyerCancer investigators. The findings will pave the way for future drug treatments to help cancer patients: bit.ly/3KZK4Z7

Congratulations to our @WCMCPathology colleagues Drs. Maria Diaz-Meco, Jorge Moscat, Juan Linares, and Dr. Tania Cid-Diaz on their new paper in @CellReports. #pathology #fibroblasts

“We found that the role of PKCi in #colorectalcancer cells is to keep the immune system at bay,” said @WCMCPathology's Dr. Jorge Moscat. #pathology

Happy National #Postdoc Appreciation Week to all #WCM postdocs, including Dr. Tania Diaz Cid (@TaniaTalu) in @WCMCPathology's Moscat & Diaz-Meco labs (moscatdiazmecolab.org). #Pathology #NPAW2021 We appreciate all of your hard work and dedication today and every day!