Goldrath Lab

Read up on how @UCSDChangLab @yeo_lab in 2020 combined multiple next-generation #genetic sequencing technologies to extensively characterize the array of cells and cellular components that contribute to ulcerative #colitis. scim.ag/Fp

Post-doc positions available in the Barber lab at the NIH/NIAID to work on T cell responses against M. tuberculosis and SARS-CoV-2 infection in mice and NHP models. If you want to work on major global public health threats the BSL3 check us out!

Dr. Heidi Cook-Andersen and team showed that UPF2 influences stage- and lineage-specific cellular and molecular events that drive progression of #epiblast cells and permit survival of the early #embryo. @Dev_journal @ucsdbiosciences 📍 bit.ly/3MRVukk

Excited to announce that the UCSD Molecular Biology department is recruiting for a tenure track assistant professor! It's a wide open search and a chance to come join an amazingly supportive, creative and fun department in beautiful San Diego. Info below: apol-recruit.ucsd.edu/JPF03378

Check out Kavita Rangan’s work in this new preprint from our lab! We show that wild squid rapidly employ RNA recoding to generate unique kinesin motor variants in different ocean temperatures. doi.org/10.1101/2022.0… 1/

Massive breakthrough in vaccination technology by the ⁦@profshanecrotty⁩ lab. Closer to an #HIVvaccine - Long-primed germinal centres with enduring affinity maturation and clonal migration | Nature nature.com/articles/s4158…

Dr. Sujan Shresta and colleagues at @LJIresearch and @UCSDMedSchool have found that #ZikaVirus forces dendritic cells to stop acting as immune cells and instead makes them churn out lipid molecules, which the virus uses to build copies of itself. 🖨️ 📌 go.nature.com/3S22892

My Goddaughter is the only black starter for Dukes volleyball team. While playing yesterday, she was called a nigger every time she served. She was threatened by a white male that told her to watch her back going to the team bus. A police officer had to be put by their bench.

In today's NYTimes article on #poliovirus in NY, an expert is quoted as saying vaccinated people are protected against the virus. This is WRONG. They are not protected against infection. They are protected from getting paralysis. Vaccinated people may still get infected.

@scharpingne Well done Shannon! So proud of you!!

@scharpingne Well done Dr Quon! You blew them away with your gorgeous study showing in vivo 3D chromatin organization for CD8 T cell differentiation and CTCF regulation of memory formation and terminal differentiation.

We're looking forward to next week's episode with Dr. Laura Mackay (@LMackayLab) from @TheDohertyInst! 📃 Read her lab's recent @BioRxivPreprint on the #epigenetic features of CD8+ tissue-resident memory #Tcells: bit.ly/3OT7IZs

Researchers led by the @GoldrathLab have developed an atlas of tissue-resident memory T cells in diverse tissue settings, boosting the prospects of new immune defense strategies to enhance immunity at vulnerable infection sites. Published in @NatImmunol. go.ucsd.edu/3nwnfTI

@KnolleLab Thank you for the generous mention! We are excited to share these findings!

#Tissueresident memory CD8 Tcells in the small intestine needs 'Hic1'cups to become tissue-resident! 😅 Amazing and comprehensive work on the differentiation of #CD8 Trm by @GoldrathLab! nature.com/articles/s4159…

Constructing transcriptional–regulatory networks identified the transcriptional repressor Hic1 as a critical regulator of TRM cell differentiation in the small intestine @GoldrathLab nature.com/articles/s4159…

How do CD8 T cells acclimate to long-lived residence in different tissues and program residence in specific tissues? Happy to see Max Heeg, Ty Crow and Amir Ferry's data hot off the press! nature.com/articles/s4159…

Our new lab publication "Lymphatic-Preserving Treatment Sequencing with Immune Checkpoint Inhibition Unleashes cDC1-Dependent Antitumor Immunity in HNSCC" @rsaddawi @Farhoud916 @O_Farrell_Aoife @vickywu003 biorxiv.org/content/10.110…

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With great sadness that we announce the passing of Dr. Matthew Mescher. Matt retired in 2015 but continued to be a valued member of CFI. He will be sorely missed & fondly remembered for his leadership & contributions to science. Our thoughts are with his family at this time.

@luglilab @ggalletti1 Looking forward to having you join us @GoldrathLab UCSD!

Ciao Giovanni @ggalletti1, you did great during your postdoc with us. And good luck with your new adventure @GoldrathLab. You deserve the official @luglilab coffee mug for long nights in the lab!