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@iatrogenicse Do you know what they used? I have to have one soon too

The anasthesia causing a massive flare of MCAS. Have to bear it and try ride it out.

@iatrogenicaware Gross and unprofessional

Real exchange between a ‘doctor’ and I, openly mocking me for suffering from emotional blunting and Anhedonia. And we still wonder why so many PSSD victims commit suicide?

@pssdganjedi Sorry to hear. What antipsychotics if you and what was the diagnosis if you don’t mind me asking?

@B04014076 lexapro and antipsychotics

i havent felt any emotion for 4+ years. this is literal hell, to be robbed of your emotions, the very thing that makes you human and will there ever be any justice, a cure? no there wont be anything, im condemned to living like this for the rest of my life because i trusted docs

@sanilrege @GabiHartaiM @psycheureka Do you have any more posts about dysautonomia/treatment? I was diagnosed with small fiber neuropathy/autonomic neuropathy through a punch biopsy. I have a great neurologist but haven’t started any treatment yet.

@GabiHartaiM @psycheureka Here is an example of links. Clonidine is an evidence based treatment that treats POTS and Anxiety ( hyperarousal ) Component causes can come together to exacerbate phenomena. Which is why we have affective immunology.

If You Think “Psychosomatic” Means “Not Real,” You’re Behind. 🚨 A real understanding of “psychosomatic” can be life-changing for both doctor and patient because it shifts the question from “is it real?” to “what is the system trying to regulate ?” The word itself comes from ‘psyche’ and ‘soma’ but psyche now means far more than ‘mind’ The irony is that the deeper you understand mind-brain–body regulation - the more you accept how much regulation happens outside conscious control: autonomic, immune, endocrine, and predictive brain–body loops running in the background. 🔄 Most of our actions even are automatised. Any clinician who dismisses psychosomatic as outdated isn’t rejecting a concept that belongs to history, they’re signalling an education gap. ❌ Neuroscience has changed our understanding of psychosomatic . It’s for us to understand it now. In many conditions ‘psychosomatic’ is a loss of regulation : a brain–body system flooded with signals that show up as symptoms across mind, body, and behaviour, all aiming to achieve one broad goal: to regain stability. So ask yourself: how can we treat dysregulation without understanding regulation? Sometimes the benefit isn’t the supplement or the exercise routine alone - it’s the repeatable ritual that teaches the nervous system safety: same wake time, same light exposure, same walk, same wind-down - predictability becomes the active ingredient. If we don’t understand how the brain and body predict, conserve energy, detect threat, and restore balance, we’ll keep focusing on symptoms only- while the system keeps ‘producing’ them to do its real job: survival.

@psycheureka What treatments are there for consummatory anhedonia? I feel like I have excessive seeking behavior for easy dopamine as a maladaptive response to losing the ability to feel pleasure and satisfaction.

💡 Psych Scene Tip: Differentiate between consummatory and appetitive deficits via follow-up consultations. Do not just ask if the patient "enjoys" their food; consider asking if they find themselves "looking forward" to them. Consummatory anhedonia is a failure of pleasure (opioids), while appetitive anhedonia is a failure of the "hunt" (dopamine). A lack of anticipatory eagerness signals that the SEEKING system remains in defensive shutdown.

Are We Misinterpreting Remission as Functional Recovery in Major Depressive Disorder (MDD)? Standard therapy for MDD focuses on top-down suppression of the GRIEF and PANIC Systems. While this effectively reduces mental pain, clinical data suggests it fails to reignite the subcortical SEEKING System. This leads to a "hollow remission"—patients are no longer in pain but lack the appetitive drive required for true life engagement. Here’s the neurobiological breakdown behind this phenomenon:👇🧵

I think it’s similar to how on the beginning of dealing with this I’d buy videogames and not open them because my mind still remembers it as something enjoyable yet I can’t currently enjoy it even though I want to.

I think I still look forward to something like eating either my brain remembers it as something that was enjoyable in the past or I just keep hoping the next time will be different. But regardless it’s disappointing every time.

There definitely is a distinction. After I developed anhedonia I developed what feels like excessive “seeking behavior” For example I “look forward” to eating but when I actually eat the food, there’s pretty much no joy and no satisfaction like there would be in the past.

It’s been over 4 years with sexual dysfunction anhedonia and losing my life. I think I’ll probably give up soon #pssd

That feeling is blunted and absent for me and feels so strange when I used to feel it all my life. I also can’t feel like a jump scare in a movie when I used to very strongly. It’s like that feeling of dopamine/adrenaline is absent.

Does anyone with PSSD not feel that “hype” “excitement” or “anticipation” feeling amymore? Like for example when watching a trailer for a movie, they use that strong bass to create that thrilling/exciting feeling or the adrenaline you’d feel in an action movie etc. #pssd

This was the first time I’ve had any change like that in the 4 years so I think it was from the medication but unfortunately it didn’t last even while I continued to take the Mirtazapine. It makes me think that there is just something messed up with neurotransmitters etc

But I noticed that one of the days my sexual dysfunction got better while on it early on. It wasn’t back to normal but it felt a bit better with erections feeling a bit more normal and ejaculation actually shot out instead of just dribbling out like usual.

I have a small update regarding PSSD. I ended up trying Mirtazapine but stopped after over a month since it was not helping mentally and too many side effects (restless legs, the appetite increase was too much, more foggy and depressed than normal etc) - #pssd

It also feels hollow. Between these rubber soft erections, the genital numbness and pleasureless orgasms it just seems hopeless.

Does anyone's penis feel completely different now? Since having PSSD for the last 4 years my penis feels completely rubber-like and gummy. It's like this whether erect or flaccid but even when “erect” it's not a proper erection it's more like a half one and not filled. #pssd

@SosjorgeC For me there’s no sensation, it feels like I’m touching just numb skin. It doesn’t feel good to touch like before. I can technically feel touch but there’s no sexual sensation or good feeling at all.