Benedikt Zott

Researchers at our university observed visual signal flow in a specific thalamocortical pathway, supporting key aspects of the 1981 Nobel Prize model by Hubel and Wiesel and refining the understanding of cortical processing: go.tum.de/450857 #Neuroscience 📷A.Eckert

Visit Felix today at #Sfn2025 to see his amazing work on soluble Trem2 and neuronal activity! Poster board D41, 4-5 pm.

Very excited to share my first project on human CSF dynamics using MRI and PET. Overall, a shared project with my dear colleague @m_bonhoeffer and supervision by many great people including @BZottlab and Christian Sorg.

Fantastic presentation from Felix at #ADPD2025 today. congratulations!

First #WednesdayCoffeeTalk of the year: @BZottlab on “Neuronal dysfunctions in #Alzheimer’s disease – mechanisms and implications for #therapy” Wednesday at 1 p.m. on Zoom - DM us for access info! More info: tum.de/en/news-and-ev…

Using tau and Aβ PET and MEG in older adults reveals that Aβ depositions colocalize with faster neurophysiological activity. In those also presenting tau pathology, slowed neurophysiological activity was seen, which was linked to cognitive decline nature.com/articles/s4159…

Albrecht Struppler Clinician Scientist Fellow @BZottlab featured on @BR24: Hopeful news in #Alzheimer's research. br.de/nachrichten/wi…

A new study shows a promising therapeutic approach to halting the progression of #Alzheimer's in its early stages. The team developed a #protein drug that can suppress the effects of the harmful amyloid beta #biomolecule: go.tum.de/125293 @SyNergy_Cluster 📷A.Heddergott

Finally out! Scavenging of #Abeta monomers can restore neuronal activity and synaptic function in early #Alzheimers by preventing the formation of toxic oligomers. Great collaboration with Arne Skerra, @CGrienberger and @marcaurelbusche nature.com/articles/s4146…

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Alterations in brain blood volume induced by changes in neuronal activity "pump" cerebrospinal fluid into and out of the brain. Excited to share my first project on human MRI. Collaboration with many great people including Christian Sorg and @NMRMgroup. biorxiv.org/content/10.110…

Preprint alert: A new protein-based approach to remove β-amyloid from the brain curbs neuronal hyperactivity in vivo. Great collaboration with the Konnerth lab, Arne Skerra, @CGrienberger and @marcaurelbusche .

Fiber photometry is a great technique. Given its infancy, there are not established methods for running the experiments. One issue is how to pick excitation powers for LEDs. Here, I am sharing some thoughts in my latest blog. blog.mohebial.com/led-power-tuni…

Happy to collaborate in this exciting project. Pioglitazone improves cognition but surprisingly boosts plaque load in Alzheimer's.

@ChrStaehr We have not tried this with actual recordings, but theoretically, it should be the same for any technique.

🧠Cerebral blood flow (CBF) responses depend on capillary transit time heterogeneity (CTH) when using BOLD fMRI. Broadened and delayed CBF responses may indicate⬆️CTH. Is this also true for other imaging techniques that directly measure CBF, @BZottlab?🤔 sciencedirect.com/science/articl…

Resting-state BOLD functional connectivity depends on the heterogeneity of capillary transit times. Happy to be part of this exciting work by @NMRMgroup.

Happy to share our new review article on impaired glutamatergic synaptic transmission in Alzheimer's disease, published in "Seminars in Cell & Developmental Biology" . sciencedirect.com/science/articl…